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Head Of Commercial Operations Jobs (NOW HIRING)

Head of Commercial Operations

San Diego, CA ยท On-site

$260K - $320K/yr

The Head of Commercial Operations, based in our San Diego office, will provide executive-level vision and strategic leadership to maximize the Commercial performance of ReActiv8. Reporting to the CEO ...

$175 - $213/hr

Director, Head of Commercial Operations, Princeton, NJ - Hybrid Date: Aug 10, 2026 Location: Princeton, NJ Company: Sun Pharmaceutical Industries, Inc (USA) Driven by a bold pursuit of science and ...

New

Partner with the Director of Retail (Commercial team) and Head of Commercial to understand retail operational needs and ensure the Lola Operations team has the resources and priorities to execute ...

$140 - $200/hr

Partner with the Director of Retail (Commercial team) and Head of Commercial to understand retail operational needs and ensure the Lola Operations team has the resources and priorities to execute ...

Partner with the Director of Retail (Commercial team) and Head of Commercial to understand retail operational needs and ensure the Lola Operations team has the resources and priorities to execute ...

Partner with the Director of Retail (Commercial team) and Head of Commercial to understand retail operational needs and ensure the Lola Operations team has the resources and priorities to execute ...

Head of Commercial Full Time | Remote, based in the Southeastern United States | 25%-50% travel ... The role reports directly to the CEO and works closely with Operations and Engineering. What You'll ...

Head of Commercial Full Time | Remote, based in the Southeastern United States | 25%-50% travel ... The role reports directly to the CEO and works closely with Operations and Engineering. What You'll ...

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Head Of Commercial Operations information

See salary details

$34K

$107.7K

$179.5K

How much do head of commercial operations jobs pay per year?

As of Aug 17, 2026, the average yearly pay for head of commercial operations in the United States is $107,680.00, according to ZipRecruiter salary data. Most workers in this role earn between $75,500.00 and $135,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a head of commercial operations?

To thrive as a Head of Commercial Operations, you need expertise in business development, sales strategy, financial acumen, and a proven track record in commercial leadership, often supported by a degree in business or related fields. Proficiency with CRM platforms, data analytics tools, ERP systems, and, in some industries, relevant certifications (such as Six Sigma or PMP) is highly beneficial. Exceptional leadership, negotiation, strategic thinking, and communication skills set top performers apart in this role. These abilities are crucial for driving revenue growth, optimizing operational efficiency, and aligning commercial activities with organizational objectives.

What are some typical challenges a head of commercial operations might face when aligning sales and marketing strategies?

A Head of Commercial Operations often encounters challenges in ensuring seamless alignment between sales and marketing teams, particularly in organizations where these functions have historically operated independently. Differences in priorities, communication gaps, and varied performance metrics can lead to misaligned goals. Overcoming these challenges requires establishing unified objectives, fostering cross-functional collaboration, and implementing integrated data systems to provide transparency. Proactive leadership and regular strategy sessions can help ensure both teams are working toward shared business targets.

What is the difference between Head Of Commercial Operations vs Commercial Manager?

AspectHead Of Commercial OperationsCommercial Manager
ResponsibilitiesOversees overall commercial strategy, leads multiple teams, and aligns sales, marketing, and business developmentManages specific commercial projects or regions, focuses on sales targets and client relationships
Required CredentialsTypically requires extensive experience in sales, marketing, or business development, often with leadership certificationsRequires experience in sales or marketing, often with relevant industry certifications
Work EnvironmentStrategic, leadership-focused, often in senior management settingsOperational, client-facing, often within sales or marketing teams
Industry UsageCommon in large organizations with complex commercial functionsWidely used across industries for managing commercial activities

The Head Of Commercial Operations focuses on strategic leadership and overall commercial growth, while the Commercial Manager handles specific sales or marketing projects. Both roles require relevant experience, but the Head Of Commercial Operations typically operates at a higher strategic level.

What does a Head Of Commercial Operations do?

A Head of Commercial Operations oversees a company's sales, marketing, and business development activities to drive revenue growth. They develop strategic plans, manage teams, analyze market trends, and ensure operational efficiency to meet organizational goals.
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What are the most commonly searched types of Of Commercial Operations jobs?

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What states have the most Head Of Commercial Operations jobs?

States with the most job openings for Head Of Commercial Operations jobs include:

Infographic showing various Head Of Commercial Operations job openings in the United States as of August 2026, with employment types broken down into 86% Full Time, 11% Part Time, 1% Temporary, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $107,680 per year, or $51.8 per hour.

Head of Commercial Operations

MML US Inc

San Diego, CA โ€ข On-site

$260K - $320K/yr

Full-time

Medical, Dental, Vision

Re-posted 22 days ago


Job description

This position is based onsite in San Diego, CA.

Mainstay Medical

Mainstay Medical is a medical device company focused on marketing an innovative implantable neurostimulation system, ReActiv8®, for people with disabling chronic mechanical Low Back Pain. The company is headquartered in Dublin, Ireland, with subsidiaries operating in the United States, Australia, the United Kingdom, and Germany.

The Role:

The Head of Commercial Operations, based in our San Diego office, will provide executive-level vision and strategic leadership to maximize the Commercial performance of ReActiv8. Reporting to the CEO, who is also based in San Diego, this role serves as a key member of the senior leadership team and is accountable for architecting and scaling a market-facing Commercial organization that drives sustainable revenue growth and profitability.

This individual will lead and integrate sales operations technology, territory management, pricing strategy, contracts, and business intelligence functions, ensuring full alignment of Commercial execution that achieves corporate growth objectives and investor expectations.

Position Responsibilities:

  • Own end-to-end commercial operations strategy for U.S. and international markets, with primary accountability for U.S. market performance; set the vision for scalable infrastructure that supports aggressive commercial growth.
  • Lead the development and execution of a comprehensive value strategy that integrates pricing, payer research, and health economics to optimize market positioning, pricing, contracting and reimbursement outcomes.
  • Lead the design of systems and tools (e.g., software) to enhance field communication, customer targeting, territory optimization, call patterns, etc.
  • Build, develop, and inspire high-performing teams across sales operations and business intelligence; establish a culture of accountability, analytical rigor, and commercial excellence.
  • Champion data and analytics as a strategic asset; drive adoption of business intelligence frameworks across the organization that generate actionable insights to accelerate growth and inform executive decision-making across global markets.
  • Define and execute national and regional market access contracting strategies; cultivate executive-level relationships with payers, IDNs, and key accounts to strengthen commercial positioning.
  • Establish and continuously improve operational policies, procedures, and governance frameworks that drive efficiency, compliance, and scalability across the commercial organization.
  • Represent commercial operations at the executive leadership level; serve as a vocal advocate for field and market-facing needs within the broader organization.
  • Uphold and model the values, policies, and compliance standards of the Mainstay Medical group.

Qualifications:

  • 10+ years of progressive experience in commercial operations or sales operations within the medical device or life sciences industry, with a minimum of 5 years in senior leadership roles with direct P&L responsibility.
  • Demonstrated ability to lead, in a hands-on way, the decision process on software implementation, CRM deployment, territory mapping, and the choice (and deployment) of tools to drive efficiency.
  • Proven track record as an executive leader who has built and scaled commercial operations functions in a high-growth medical device or life science environment.
  • Deep expertise in U.S. market access, reimbursement strategy, pricing, and health economics; international commercial experience strongly preferred.
  • Demonstrated ability to synthesize complex data sets — including real-world evidence, modeling, and market analytics — into executive-level strategic recommendations that drive commercial outcomes.
  • Experience leading organizations through significant growth inflection points, including team builds, system implementations, commercial territory management, and market launches.
  • Strong executive presence with the ability to influence C-suite stakeholders, board members, and external partners; skilled at building alignment across matrixed organizations.
  • Bachelor's degree required; advanced degree (MBA, MPH, or equivalent) strongly preferred.

The salary range for this position is $260,000 to $320,000/year; however, base pay offered will take into account a range of factors, including job-related knowledge, skills, and experience. The total compensation package includes a range of medical, dental, vision, financial, and other benefits, as well as equity.

Mainstay Medical is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to gender, race, color, religious creed, national origin, age, sexual orientation, gender identity, physical or mental disability, and/or protected veteran status. Mainstay Medical participates in E-Verify.