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Downstream Processing Jobs (NOW HIRING)

Manus Bio

Downstream Processing Operator

Augusta, GA · On-site

The Downstream Processing Operator is responsible for the continuing efficient operation of the fermentation plant and providing overtime support as needed for production. This includes maintenance ...

Manus Bio

Downstream Processing Operator

Augusta, GA

$17.75 - $22.50/hr

The Downstream Processing Operator is responsible for the continuing efficient operation of the fermentation plant and providing overtime support as needed for production. This includes maintenance ...

Manus

Downstream Processing Operator

Augusta, GA

The Downstream Processing Operator is responsible for the continuing efficient operation of the fermentation plant and providing overtime support as needed for production. This includes maintenance ...

Kinetic Personnel Group

Downstream Process

Tustin, CA · On-site

Downstream Process Analytics Specialist Industry: Biopharmaceutical CDMO / Biologics Manufacturing Location: Irvine, CA (Onsite) Employment Type: Full-Time Schedule: Monday–Friday | Standard ...

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How much do downstream processing jobs pay per hour?

As of Aug 2, 2026, the average hourly pay for downstream processing in the United States is $24.67, according to ZipRecruiter salary data. Most workers in this role earn between $19.71 and $28.12 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Downstream Processing position, and why are they important?

To thrive in Downstream Processing, you typically need a background in biochemistry, chemical engineering, or a related field, along with experience in purification and separation techniques. Familiarity with technical tools such as chromatography systems, filtration units, and process control software, as well as cGMP certification, is often required. Strong attention to detail, problem-solving skills, and effective teamwork are valuable soft skills for this role. These competencies ensure efficient production, product quality, and compliance in highly regulated biopharmaceutical environments.

What is the best job in science stream?

The best job in the science stream depends on individual interests and skills, but roles such as research scientist, biomedical engineer, or data analyst are highly regarded. These positions often require relevant degrees, technical skills, and sometimes certifications, and they offer opportunities in research, healthcare, and technology sectors.

What are the typical daily responsibilities of someone working in Downstream Processing?

In Downstream Processing, your daily activities often include operating and optimizing purification systems, conducting in-process testing, and meticulously documenting process parameters and results. You’ll collaborate closely with upstream teams, quality control labs, and engineering staff to troubleshoot and improve workflows. Managing equipment maintenance, adhering to safety and compliance standards, and actively participating in process development projects are also key facets of the job. This hands-on role is essential for ensuring the purity and consistency of biopharmaceutical products.

What is a Downstream Processing job?

A Downstream Processing (DSP) job involves purifying and recovering biomolecules, such as proteins or vaccines, after fermentation or cell culture. Professionals in this role use techniques like filtration, chromatography, and centrifugation to ensure product purity and quality. They work in industries like pharmaceuticals, biotechnology, and bioprocessing. Key responsibilities include optimizing purification processes, troubleshooting equipment, and ensuring compliance with regulatory standards.

What is a downstream technician?

A downstream technician is responsible for the purification and formulation of biopharmaceutical products after the initial production phase. They operate equipment such as chromatography systems and filtration units, following strict safety and quality protocols, often requiring knowledge of Good Manufacturing Practices (GMP).

What are the life science jobs?

Downstream processing jobs in the life sciences involve the purification and recovery of biological products such as proteins, vaccines, and antibodies. These roles typically require knowledge of bioprocessing techniques, laboratory skills, and familiarity with equipment like chromatography systems. Positions may include process technicians, bioprocess engineers, and quality control specialists working in manufacturing or research settings.

What is the role of a bioprocess engineer?

A bioprocess engineer designs, develops, and optimizes processes for producing biological products such as vaccines, therapeutics, and enzymes. They work with bioreactors, chromatography, and other downstream processing techniques to ensure efficient and scalable manufacturing, often requiring knowledge of biochemistry, engineering principles, and regulatory standards.
More about Downstream Processing jobs
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Downstream Processing jobs near you
Infographic showing various Downstream Processing job openings in the United States as of July 2026, with employment types broken down into 95% Full Time, 1% Part Time, and 4% Contract. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution, with an average salary of $51,319 per year, or $24.7 per hour.

Downstream Processing Operator

Danimer Scientific

Winchester, KY • On-site

$16.50 - $20.75/hr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 5 days ago

Job description

Benefits:
  • 401(k)
  • 401(k) matching
  • Bonus based on performance
  • Dental insurance
  • Health insurance
  • Training & development
  • Vision insurance
  • Wellness resources

NOW INTERVIEWING FOR FUTURE OPPORTUNITIES:
Downstream Processing (DSP) Operator
Winchester, KY | Biodegradable Plastics
Schedule: 12 Hour Shifts on a 2-2-3 pattern (Day or Night Availability Required)
Employment Type: Non-exempt | Full-time
At Danimer Scientific, we're building the future of sustainable materials-and that takes skilled operators who care about quality, safety, and doing things the right way. As a Downstream Processing (DSP) Operator, you'll play a hands-on role in producing advanced materials in a cGMP manufacturing environment while working with a collaborative, safety-focused team.
If you enjoy technical work, problem-solving, and being part of a process that truly matters, we'd love to meet you.
What You'll Do
Under the guidance of a Team Leader and Manufacturing Management, the DSP Operator is responsible for executing day-to-day production activities in the Downstream Processing area. This role is hands-on, detail-oriented, and critical to maintaining product quality and process reliability.
Key Responsibilities Include:
  • Operate and monitor downstream processing equipment and utilities
  • Start/stop pumps, open/close manual valves, collect samples, and respond to process alarms
  • Monitor process conditions and adjust parameters to maintain stability
  • Accurately complete batch records, logbooks, and production documentation in compliance with cGMP standards
  • Review production documentation for accuracy, completeness, and quality compliance
  • Add chemicals and process additives based on calculations and procedures
  • Troubleshoot process or equipment deviations and initiate corrective actions
  • Communicate production metrics, issues, and shift handoffs clearly
  • Maintain clean, organized, and audit-ready work areas per GMP standards
  • Participate in continuous improvement initiatives related to safety, quality, and efficiency
  • Train and support new or developing operators
  • Serve as a safety leader-stop production when a quality or safety concern is identified

What We're Looking For
Required Qualifications
  • High school diploma or GED
  • Minimum of 2 years of experience in a manufacturing or industrial environment
  • Ability to work independently and as part of a team
  • Strong attention to detail and commitment to documentation accuracy
  • Mechanically inclined with strong problem-solving skills
  • Comfortable working with automated systems and manual equipment
  • Proficient with basic computer systems (Microsoft Suite)

Preferred Qualifications
  • Associate degree in applied process technologies or related field
  • Prior experience in biotech, chemical, or cGMP manufacturing
  • Working knowledge of GMP, safety protocols, and quality systems

Work Schedule
  • Full-time, 12-hour shifts
  • Days or nights, including weekends, holidays, and overtime as required

Physical & Work Environment Requirements
  • Ability to stand, walk, bend, stoop, and perform repetitive tasks for extended periods
  • Ability to lift up to 50 lbs occasionally and climb ladders/stairs
  • Work in hot, cold, loud, and industrial manufacturing environments
  • Use of PPE including hearing protection in designated areas
  • Exposure to moving mechanical parts, vibration, fumes, and airborne particles

Why Danimer?
Mission-driven work (bye, plastic pollution)
Growth opportunity
Great pay + benefits
Team-first culture
Equal Opportunity Employer
Danimer Scientific provides equal employment opportunities to all employees and applicants without regard to race, color, religion, sex, national origin, age, disability, genetics, or any other status protected by law. We comply with all federal, state, and local laws governing nondiscrimination in every location where we operate.
We strictly prohibit any form of workplace harassment or discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, or any other protected status.
Apply now and be part of something bigger
We're advancing the future of sustainable materials - and we're not alone!
Our commitment to replacing traditional plastics with biodegradable, compostable solutions is now backed by a strong, new partnership with - a global leader in material science. Together, we're turning shared vision and shared values into real-world impact.
Join us as we celebrate a partnership that moves sustainability forward!

Apply