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Downstream Processing Jobs in Gaithersburg, MD (NOW HIRING)

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Monitor processes using automated production systems and controls with supervision. * Obtain and perform in-process sampling. * Prepare buffers and solutions needed for Downstream activities ...

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DevSecOps / Sys Admin

Columbia, MD · On-site

$210 - $228/hr

Design, implement, and support dataflow architectures that move information securely from front-end systems to back-end services and downstream processing environments. * Analyze interfaces, data ...

Design, implement, and support dataflow architectures that move information securely from front-end systems to back-end services and downstream processing environments. * Analyze interfaces, data ...

Data Engineer with Security Clearance

Mclean, VA · On-site

$115K - $139K/yr

Produce and consume streaming events (e.g., Kafka topics) to support near-real-time signal delivery and downstream processing * Partner with data architecture and domain SMEs to define and maintain ...

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Downstream Processing information

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How much do downstream processing jobs pay per hour?

As of Aug 27, 2026, the average hourly pay for downstream processing in Gaithersburg, MD is $26.66, according to ZipRecruiter salary data. Most workers in this role earn between $21.30 and $30.38 per hour, depending on experience, location, and employer.

What is downstream processing?

A Downstream Processing (DSP) job involves purifying and recovering biomolecules, such as proteins or vaccines, after fermentation or cell culture. Professionals in this role use techniques like filtration, chromatography, and centrifugation to ensure product purity and quality. They work in industries like pharmaceuticals, biotechnology, and bioprocessing. Key responsibilities include optimizing purification processes, troubleshooting equipment, and ensuring compliance with regulatory standards.

What are the typical daily responsibilities of someone working in downstream processing?

In Downstream Processing, your daily activities often include operating and optimizing purification systems, conducting in-process testing, and meticulously documenting process parameters and results. You’ll collaborate closely with upstream teams, quality control labs, and engineering staff to troubleshoot and improve workflows. Managing equipment maintenance, adhering to safety and compliance standards, and actively participating in process development projects are also key facets of the job. This hands-on role is essential for ensuring the purity and consistency of biopharmaceutical products.

What are the key skills and qualifications needed to thrive in downstream processing, and why are they important?

To thrive in Downstream Processing, you typically need a background in biochemistry, chemical engineering, or a related field, along with experience in purification and separation techniques. Familiarity with technical tools such as chromatography systems, filtration units, and process control software, as well as cGMP certification, is often required. Strong attention to detail, problem-solving skills, and effective teamwork are valuable soft skills for this role. These competencies ensure efficient production, product quality, and compliance in highly regulated biopharmaceutical environments.

What does downstream processing involve?

Downstream processing involves the purification and recovery of products such as proteins, enzymes, or pharmaceuticals from bioreactors. It includes steps like filtration, chromatography, and concentration to ensure product quality and safety, often requiring knowledge of bioprocessing techniques and quality control standards.

What are popular job titles related to Downstream Processing jobs in Gaithersburg, MD?

For Downstream Processing jobs in Gaithersburg, MD, the most frequently searched job titles are:

What job categories do people searching Downstream Processing jobs in Gaithersburg, MD look for?

The top searched job categories for Downstream Processing jobs in Gaithersburg, MD are:

Infographic showing various Downstream Processing job openings in Gaithersburg, MD as of August 2026, with employment types broken down into 1% As Needed, 75% Full Time, 18% Part Time, 1% Temporary, 4% Contract, and 1% Nights. Highlights an 89% Physical, 4% Hybrid, and 7% Remote job distribution, with an average salary of $55,447 per year, or $26.7 per hour.

Scientist Downstream Processing - Columbia, MD

Columbia, MD • On-site

DSM
Marketing • 11 - 50 employees

$100K - $135K/yr

Full-time

Medical, Retirement, PTO

Posted 7 days ago


Job description

Scientist, Downstream Process Development
Location: Columbia, MD
We are seeking a talented and motivated Scientist with expertise in Downstream Processing (DSP), ideally within the field of Biotechnology, to strengthen our research team at the Columbia Biotechnology research hub of dsm-firmenich. In this role, you will lead and contribute to the development of innovative biotechnological processes that enable production of ingredients and products used across a wide range of applications.
The Columbia site serves as the Center of Excellence for Lipids within dsm-firmenich. The successful candidate will bring experience with oil and lipid chemistry, emulsions, and separations technologies. We are looking for a natural communicator, orally and in writing, as well as a team player who can think, act, and discuss scientific concepts and discoveries across disciplines in a constructive and collaborative way. This role offers the opportunity to be innovative with an entrepreneurial way of working. In addition, you will have the opportunity to lead the planning and execution of complex science and research projects including reviews, reporting, and stakeholder management.
Key Responsibilities:
  • Scientific Excellence and Thought Leadership: Apply relevant scientific and engineering knowledge in separations processes to projects and interconnected processes with an eye towards enabling environmentally beneficial and cost competitive biobased solutions to global challenges around nutrition, health, and beauty.
  • Process Development and Optimization: Design, execute, and analyze downstream processes at bench scale. Drive opportunities to optimize existing processes at production scale, with a thorough understanding of scale down, scale up, and tech transfer.
  • Cross-functional collaboration: Work closely with Strain Improvement, Fermentation, Analytical, Manufacturing, and Quality to resolve complex bioprocess challenges. Visualize and present data and conclusions, convincing stakeholders to move solutions from the lab towards implementation.

We Offer:
  • A dynamic R&D environment where you can contribute to impactful innovations.
  • A diversity of exciting projects related to lipids, foods and products used everyday by millions of people.
  • A diverse, international, and interdisciplinary team of industry-leading researchers with a well-equipped research facility.
  • Supportive career development, with opportunities for both vertical and lateral growth.
  • The opportunity to be a part of a company both building upon and shaping a strong legacy through breakthrough industrial innovations and technology.

You Bring:
  • BS in Chemical Engineering, Biotechnology, Bioprocess Engineering, or related field with 5+ years of hands-on experience in industry. MS or PhD in applicable disciplines can be considered partially in lieu of industrial experience.
  • A proven track record on process and product innovation with demonstrated hands-on experience with lab and/or pilot scale bioprocessing recovery equipment.
  • Keen understanding of unit operations, M&E balances, and separation technologies, with experience developing DSP trains and interconnected modeling approaches thereof.
  • Understanding and experience applying statistics and DOE in development of experimental workplans; Six Sigma certification is a plus.
  • A strong sense of ownership, accountability, and motivation with good prioritization and organizational skills.
  • A collaborative spirit - you thrive in cross-functional, international teams and show initiative when contributing to project work.

The salary or hourly wage scale provided reflects the pay range dsm-firmenich expects to pay the successful candidate for the position. Individual pay offered will be based on the applicant's job-related skills, experience, relevant education, or training, and primary work location. This position is also eligible for bonuses and benefits, which are not included in the pay scale provided. Salary $100,000-$135,000.
In addition to base salary, we also offer a comprehensive total rewards package, inclusive of annual incentive pay, a retirement savings plan, health care coverage, paid time off, recognition programs and a broad range of other benefits. All benefits and incentives are subject to eligibility requirements.
About dsm-firmenich
At dsm-firmenich, we don't just meet expectations - we go beyond them.
Join our global team powered by science, creativity, and a shared purpose: to bring progress to life.
From elevating health to making fortified food and sustainable skincare, the impact of your work here will be felt by millions - every single day. Whether it's fragrance that helps you focus, alternative meat that's better for the planet, or reducing sugar without losing flavor, this is where you help shape the future of nutrition, health, and beauty for everyone, everywhere.
And while you're making a difference, we'll make sure you're growing too. With learning that never stops, a culture that lifts you up and the freedom to move across businesses, teams, and borders. Your voice matters here. And your ideas? They're essential to our future.
Because real progress only happens when we go beyond, together.
The application process
Interested in this position? Please apply online by uploading your resume in English.
Inclusion, belonging and equal opportunity statement
At dsm-firmenich, we believe being a force for good starts with the way we treat each other. When people feel supported, included, and free to be themselves, they do their best work - and that's exactly the kind of culture we're building. A place where opportunity is truly equal, authenticity is celebrated, and everyone has the chance to grow, contribute, and feel they belong.
We're proud to be an equal opportunity employer, and we're serious about making our hiring process as fair and inclusive as possible. From inclusive language and diverse interview panels to thoughtful sourcing, we're committed to reflecting the world we serve.
We welcome candidates from all backgrounds - no matter your gender, ethnicity, sexual orientation, or anything else that makes you, you.
And if you have a disability or need any support through the application process, we're here to help - just let us know what you need, and we'll do everything we can to make it work.
Agency statement
We're managing this search directly at dsm-firmenich. If you're applying as an individual, we'd love to hear from you. We're not accepting agency submissions or proposals involving fees or commissions for this role.