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Downstream Processing Jobs in California (NOW HIRING)

Kinetic Personnel Group

Downstream Process

Tustin, CA · On-site

Downstream Process Analytics Specialist Industry: Biopharmaceutical CDMO / Biologics Manufacturing Location: Irvine, CA (Onsite) Employment Type: Full-Time Schedule: Monday–Friday | Standard ...

Debut Biotech

Staff Process Engineer

San Diego, CA · On-site

This individual will serve as the organization's subject matter expert in downstream processing, guiding a team of scientists and engineers through process development at bench, pilot, and ...

New

Debut Biotech

Staff Process Engineer

San Diego, CA · On-site

This individual will serve as the organization's subject matter expert in downstream processing, guiding a team of scientists and engineers through process development at bench, pilot, and ...

New

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Downstream Processing information

See California salary details

$13

$24

$35

How much do downstream processing jobs pay per hour?

As of Aug 2, 2026, the average hourly pay for downstream processing in California is $24.35, according to ZipRecruiter salary data. Most workers in this role earn between $19.47 and $27.74 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Downstream Processing position, and why are they important?

To thrive in Downstream Processing, you typically need a background in biochemistry, chemical engineering, or a related field, along with experience in purification and separation techniques. Familiarity with technical tools such as chromatography systems, filtration units, and process control software, as well as cGMP certification, is often required. Strong attention to detail, problem-solving skills, and effective teamwork are valuable soft skills for this role. These competencies ensure efficient production, product quality, and compliance in highly regulated biopharmaceutical environments.

What is the best job in science stream?

The best job in the science stream depends on individual interests and skills, but roles such as research scientist, biomedical engineer, or data analyst are highly regarded. These positions often require relevant degrees, technical skills, and sometimes certifications, and they offer opportunities in research, healthcare, and technology sectors.

What are the typical daily responsibilities of someone working in Downstream Processing?

In Downstream Processing, your daily activities often include operating and optimizing purification systems, conducting in-process testing, and meticulously documenting process parameters and results. You’ll collaborate closely with upstream teams, quality control labs, and engineering staff to troubleshoot and improve workflows. Managing equipment maintenance, adhering to safety and compliance standards, and actively participating in process development projects are also key facets of the job. This hands-on role is essential for ensuring the purity and consistency of biopharmaceutical products.

What is a Downstream Processing job?

A Downstream Processing (DSP) job involves purifying and recovering biomolecules, such as proteins or vaccines, after fermentation or cell culture. Professionals in this role use techniques like filtration, chromatography, and centrifugation to ensure product purity and quality. They work in industries like pharmaceuticals, biotechnology, and bioprocessing. Key responsibilities include optimizing purification processes, troubleshooting equipment, and ensuring compliance with regulatory standards.

What is a downstream technician?

A downstream technician is responsible for the purification and formulation of biopharmaceutical products after the initial production phase. They operate equipment such as chromatography systems and filtration units, following strict safety and quality protocols, often requiring knowledge of Good Manufacturing Practices (GMP).

What are the life science jobs?

Downstream processing jobs in the life sciences involve the purification and recovery of biological products such as proteins, vaccines, and antibodies. These roles typically require knowledge of bioprocessing techniques, laboratory skills, and familiarity with equipment like chromatography systems. Positions may include process technicians, bioprocess engineers, and quality control specialists working in manufacturing or research settings.

What is the role of a bioprocess engineer?

A bioprocess engineer designs, develops, and optimizes processes for producing biological products such as vaccines, therapeutics, and enzymes. They work with bioreactors, chromatography, and other downstream processing techniques to ensure efficient and scalable manufacturing, often requiring knowledge of biochemistry, engineering principles, and regulatory standards.
What are the most commonly searched types of Downstream Processing jobs in California? The most popular types of Downstream Processing jobs in California are:
What are popular job titles related to Downstream Processing jobs in California? For Downstream Processing jobs in California, the most frequently searched job titles are:
What job categories do people searching Downstream Processing jobs in California look for? The top searched job categories for Downstream Processing jobs in California are:
Downstream Processing jobs near you
Infographic showing various Downstream Processing job openings in California as of July 2026, with employment types broken down into 83% Full Time, and 17% Part Time. Highlights an 100% In-person job distribution, with an average salary of $50,647 per year, or $24.3 per hour.

Process Engineer, Downstream Processing

Visolis

Hayward, CA • On-site

Full-time

Re-posted 23 days ago

Job description


The Process Engineer with our Downstream Processing team will be responsible for providing support activities in the catalysis and process development areas. Specifically, the person in this position will contribute to the development of the production process and catalyst development strategies through the operation of lab-scale reactors to quantitatively characterize catalysts for the production of renewable chemicals. The person will work closely with engineering, molecular biology and analytical teams to increase the yield and productivity of the processes. The scientist will promote a strong health, safety and environment culture on site and within the team.
Primary Responsibilities
  • Assist in the scale up of Visolis' patented processes to make a range of bio-based chemical products.
  • Design experiments to test catalysts.
  • Perform various unit operations and different purification/separation processes.
  • Run analytical instruments for quantification.
  • Collect and process samples for products of interest.
  • Analyze and report data to enable appropriate interpretation and follow up experiments.
  • Identify and report opportunities for improvement and assist to implement as needed.
  • Proactively communicate information through appropriate verbal and written means and actively participate in meetings.
  • Understand and follow department and corporate guidelines, compliance and safety rules and procedures related to duties.
  • Perform other reasonably related duties not expressly written in this job description as may be assigned from time to time.

Job Qualifications
Minimum Qualifications
  • B.S. or higher in Chemical Engineering
  • Flexibility in working schedule to accommodate experimental needs.
  • Ability to lift approximately 10-20 kg routinely.
  • Eligibility to work in the US (no visa sponsorship/transfer).

Preferred Qualifications
  • Industrial engineering experience, including process development for chemical production processes.
  • Familiar with HPLC analysis.
  • Strong computer and analytical skills, statistical analysis and reporting experience.
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About Visolis

Sourced by ZipRecruiter

Industry

Clean energy semiconductors manufacturing

Company size

1 - 10 Employees

Headquarters location

Hayward, CA, US

Year founded

2012

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