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How much do downstream processing jobs pay per hour?

As of Jun 22, 2026, the average hourly pay for downstream processing in the United States is $24.67, according to ZipRecruiter salary data. Most workers in this role earn between $19.71 and $28.12 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Downstream Processing position, and why are they important?

To thrive in Downstream Processing, you typically need a background in biochemistry, chemical engineering, or a related field, along with experience in purification and separation techniques. Familiarity with technical tools such as chromatography systems, filtration units, and process control software, as well as cGMP certification, is often required. Strong attention to detail, problem-solving skills, and effective teamwork are valuable soft skills for this role. These competencies ensure efficient production, product quality, and compliance in highly regulated biopharmaceutical environments.

What jobs pay $10,000 a month without a degree?

In downstream processing and related fields, high-paying roles such as process engineers, quality managers, or technical specialists can reach or exceed $10,000 per month with relevant experience and industry knowledge. These positions often require technical skills, certifications, or on-the-job training rather than a formal degree, especially in manufacturing, biotech, or pharmaceutical environments.

What is the role of downstream processing?

Downstream processing in a job context involves the purification, formulation, and packaging of products, such as biopharmaceuticals or chemicals, after initial production. It requires skills in chromatography, filtration, and aseptic techniques to ensure product quality and compliance with regulatory standards.

What is the highest paying biotech job?

In downstream processing, senior roles such as Director of Downstream Processing or Vice President of Bioprocessing tend to be the highest paying, often earning six-figure salaries. These positions require extensive experience, leadership skills, and expertise in bioprocessing techniques and regulatory compliance.

What is the highest paying job in food engineering?

In food engineering, senior roles such as Food Processing Plant Managers or Food Technology Directors tend to have the highest salaries, often exceeding six figures. These positions typically require extensive experience, advanced degrees, and strong leadership skills, with compensation influenced by company size and location.

What are the typical daily responsibilities of someone working in Downstream Processing?

In Downstream Processing, your daily activities often include operating and optimizing purification systems, conducting in-process testing, and meticulously documenting process parameters and results. You’ll collaborate closely with upstream teams, quality control labs, and engineering staff to troubleshoot and improve workflows. Managing equipment maintenance, adhering to safety and compliance standards, and actively participating in process development projects are also key facets of the job. This hands-on role is essential for ensuring the purity and consistency of biopharmaceutical products.

What is a Downstream Processing job?

A Downstream Processing (DSP) job involves purifying and recovering biomolecules, such as proteins or vaccines, after fermentation or cell culture. Professionals in this role use techniques like filtration, chromatography, and centrifugation to ensure product purity and quality. They work in industries like pharmaceuticals, biotechnology, and bioprocessing. Key responsibilities include optimizing purification processes, troubleshooting equipment, and ensuring compliance with regulatory standards.

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Downstream Processing jobs near you
Infographic showing various Downstream Processing job openings in the United States as of June 2026, with employment types broken down into 1% As Needed, 84% Full Time, 14% Part Time, and 1% Nights. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $51,319 per year, or $24.7 per hour.

(Sr) Technician, Downstream Process

GenScript/ProBio

Hopewell, NJ • On-site

$60K - $75K/yr

Full-time

Posted 11 days ago

Job description

About GenScriptGenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.

About ProBio:

ProBio, a subsidiary of GenScript, is a global CDMO offering end-to-end services from discovery to GMP for plasmids, antibodies, and cell & gene therapies. We bring together multidisciplinary expertise to accelerate development and manufacturing through customized, and comprehensive services. ProBio has established companies in the United States, the Netherlands, South Korea, and China (Hong Kong, Shanghai, and Nanjing) and other regions to serve global customers, and has helped customers in the United States, Europe, Asia Pacific and other regions obtain more than 150 IND approvals since October 2017.

About the job:

The (Sr) Technician, Downstream Process will work within the Downstream Processing group and performs the following activities while executing Downstream operations:

  • Preparation of stock solutions, and buffers.
  • Filtration of stock solutions and buffers.
  • Operates all production equipment in assigned functional area such as single use chromatography systems, chromatography columns, other disposable Bioprocess equipment, and solution preparation equipment as per written procedures.
  • The (Sr) Technician, Downstream Process supports relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.

Location: Pennington, NJ

Responsibilities:

  • Executes routine complex manufacturing assignments per written procedures; recognizes deviations from procedures and raises issue to management for resolution.
  • Adheres to current Good Manufacturing Practices (cGMP) and Standard Operating Procedures (SOPs).
  • Performs routine microbial and mammalian purification. Monitors chromatography and tangential flow filtration (TFF) systems during processing.
  • Weighs and checks raw materials, assembles process equipment, and monitors processes.
  • Completes work instructions and maintains clean room environment to comply with regulatory requirements
  • Operates all production equipment in assigned functional area such as single use chromatography systems, chromatography columns, other disposable Bioprocess equipment, and solution preparation equipment as per written procedures.
  • Authors solution preparation Master Batch Records (MBRs) by transferring technical information from scientific and development documents.
  • Proposes and routes revisions to existing SOP's for functional area equipment.
  • Works to become proficient on common bioprocessing equipment.
  • Conducts Safety and GMP self-auditing walkthroughs, documenting observations for assignment and closure dates. Tracks and ensures closure of observations.
  • Logs and submits samples in Laboratory Information Management System (LIMS); tracks results and compiles data.
  • Reviews own work for completeness on executed Master Batch Records (MBRs).
  • Coordinate the tracking and return of executed records to Quality department for review.
  • Coordinates with Logistics to ensure needed materials are delivered to the production area timely. Monitors future needs against material supply to alert Logistics of shortfalls.
  • Performs other tasks and assignments as needed and specified by management.

Qualifications:

  • Bachelor's degree in science or engineering with a 0 – 5 years relevant experience or an Associate's degree in science or engineering with a minimum of 3 years relevant experience or a High school diploma with a minimum of 7 years relevant experience.
  • Demonstrated ability to follow written instructions and procedures.
  • Demonstrated ability to pay strict attention to detail.
  • Proficiency with Microsoft Office.
  • Excellent verbal and written communication and skills.
  • Ability to work collaboratively as part of a team, in a fast-paced, matrixed, team environment consisting of internal and external team members.

The estimated pay range for the role is between $60,000 - $75,000 based on qualifications and experience.

#PB

#AH

GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.

Please note: Genscript USA Inc./ProBio Inc. will only contact candidates through verified application sources. GenScript/Probio does not request personal information from candidates through individual email or any other platform.