Senior Research Associate, Pharmacology

Company Overview:

Vividion is a next generation biotechnology company based in San Diego that is leveraging its proprietary chemical proteomics platform to conduct proteome-wide footprinting of drug-protein interactions with unprecedented breadth and precision. Our technology allows us to screen, identify and optimize novel drugs that selectively bind virtually any protein, including proteins previously considered “undruggable”. Our pipeline and emerging programs reflect a matured and productive platform capable of delivering first in class drugs utilizing novel mechanisms of action (allosteric inhibitors, protein-protein interaction inhibitors, functional activators, degraders etc.) against undruggable targets in the oncology and immunology space.

We are uniquely structured with opportunities for all scientists to contribute to both established programs as well as ongoing early target selection, screens and validation. We prize scientific excellence, creativity, team players and we are committed to continued innovation. We have worked hard to create a collaborative and dynamic work culture where your ideas and discoveries are valued and will have an impact. We are growing and there are opportunities for mentorship and career progression.

Vividion was ranked #2 mid-size company on The San Diego Union-Tribune's 2022 and 2023 Top Workplaces list.

Job Summary:

Vividion is seeking a highly motivated individual to contribute to the identification and development of novel small-molecule drugs to address unmet medical needs in immune-inflammatory diseases. The successful candidate will have extensive hands-on experience designing and executing short term in vivo studies for pharmacodynamic activity, execute chronic mechanistic inflammation/autoimmune models for efficacy, and conduct ex vivo analysis of mechanism of action with minimal guidance.

Education and Experience requirements:

• B.S. / M.S. in Biology (or Immunology/Pharmacology/ or related) with at least 3- 5 years of industry /CRO drug discovery experience. Individuals with relevant experience in the academic setting will also be considered.
• Ability to managing assigned projects, independently design, plan, and execute in vivo experiments, conduct ex vivo analysis or in vitro experiments to address drug mechanism-of-action and disease-focused hypotheses, troubleshoot experiments as needed, analyze, interpret data, and plan follow up experiments.
• Strong experience in developing and/or executing in vivo models, including dosing (PO, IV, IP, SC), blood and tissue collection, necropsy, and other biometric data collection.
• Hands-on experience with ex vivo analysis employing contemporary cellular, molecular, and immunological techniques such as PCR or NanoString, flow cytometry, and protein analysis by Western/MSD/ELISA etc.
• Demonstrated experience in data interpretation, analysis, and presentation to internal stakeholders.

Preferred Experience and Skills:

• Immunology/inflammation research experience. Individuals with strong academic research track record will also be considered.

Required Key Attributes:

• Scientific curiosity.
• Strong communication skills.
• Strong problem-solving skills.
• Experience to work in a matrix environment and as a strong individual contributor in research teams.
• Ability to multitask and adapt to changes in research priorities while delivering high quality results under tight timelines.

Pay & Benefits:

The annual base salary for this position ranges from $80,000 to $88,000 depending on relevant skills, experience, and education. In addition, this position is eligible for target bonus, long-term-incentives, 401k retirement savings plan with company match, and a comprehensive benefits package which includes medical, dental, vision, life, and disability insurance. Relocation assistance may be available based on business needs and/or eligibility.

EEO & Employment Eligibility:

Vividion Therapeutics, Inc. is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Privacy Policy:

The protection of your personal information is a commitment we take seriously. For information regarding our Privacy Policy (CA candidates) please visit https://vividion.com/publication/privacy-noticeforcalifornia-candidates/.