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Variant Scientist Jobs (NOW HIRING)

Ambry Genetics

$110K - $114K/yr

The Clinical Genomic Scientist II is highly proficient in variant classification guidelines and in following report generation protocols to meet requirements for quality and turnaround time. The ...

Natera

OR · On-site

... robust performance for variant calling, fusion detection, and automated quality control ... PhD in Bioinformatics, Computer Science, Engineering, Statistics, Cancer Biology or similar field ...

Natera

Senior Bioinformatics Scientist

San Carlos, CA · On-site

... robust performance for variant calling, fusion detection, and automated quality control ... PhD in Bioinformatics, Computer Science, Engineering, Statistics, Cancer Biology or similar field ...

Variant Bio

Executive Administrator

Seattle, WA · Hybrid

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Experience at an early-stage biotech, life sciences, or clinical-stage company. * Background ... COMPENSATION & PERKS At Variant Bio, we're building something meaningful and we believe supporting ...

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How much do variant scientist jobs pay per hour?

As of Aug 15, 2026, the average hourly pay for variant scientist in the United States is $47.05, according to ZipRecruiter salary data. Most workers in this role earn between $34.13 and $59.62 per hour, depending on experience, location, and employer.

What does a variant scientist do?

As a variant scientist, you work for a research laboratory in a university or a medical facility to test and study variations of genes and the effects they have on human development. As part of your duties, you aid in the development of new tests to discover gene abnormalities, perform analysis on patient samples to identify possible mutations, and record your findings to assist in scientific research. You also have heavy reporting responsibilities that may require in-depth computer and writing skills, the ability to analyze data, and strong attention to detail. In this role, you may cater to a specific health field, like pediatrics or oncology.

What are some common challenges faced by variant scientists in interpreting genetic data, and how are these typically addressed within a team?

Variant Scientists often encounter challenges such as distinguishing between benign and pathogenic variants, managing large volumes of sequencing data, and staying updated with rapidly evolving genetic databases. These challenges are typically addressed by collaborating closely with bioinformaticians, clinical geneticists, and laboratory personnel to review findings and validate interpretations. Regular team meetings, use of standardized classification guidelines like ACMG, and leveraging advanced software tools help ensure accurate and consistent variant analysis.

What is a variant scientist?

Variant Scientists are professionals who analyze genetic variants—differences in DNA sequences—to determine their significance in health and disease. They interpret genomic data, often from whole-genome or exome sequencing, to assess whether specific variants may cause or contribute to medical conditions. Their work is crucial in clinical genetics, precision medicine, and biomedical research, helping guide patient diagnosis and treatment. Variant Scientists collaborate with clinicians, bioinformaticians, and laboratory personnel to provide accurate and actionable genetic insights.

What are the key skills and qualifications needed to thrive as a variant scientist, and why are they important?

To thrive as a Variant Scientist, you need a solid background in genetics, molecular biology, and bioinformatics, typically supported by an advanced degree such as a PhD or MSc in a related field. Familiarity with next-generation sequencing (NGS) platforms, variant annotation tools, and data analysis software like GATK or ANNOVAR is essential. Strong analytical thinking, attention to detail, and effective communication skills help you interpret complex genetic data and collaborate with multidisciplinary teams. These skills ensure accurate variant interpretation, drive discoveries, and support precision medicine initiatives.
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Variant Scientist jobs near you
Infographic showing various Variant Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 87% Full Time, 7% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $97,868 per year, or $47.1 per hour.

Clinical Genomic Scientist II (genome analyst): REMOTE, USA

Ambry Genetics

Remote

$110K - $114K/yr

Full-time

Re-posted 7 days ago

Job description

Compensation:

$110,000-$114,000 annually

Clinical Genomics Scientist II - Remote US:

Experienced reporting position for individuals, typically genetic counselors or PhD scientists, with clinical laboratory experience.

Responsibilities include:

interpreting diagnostic test results, review and summary of relevant medical literature, and/or review and summary of clinical information. The Clinical Genomic Scientist II is highly proficient in variant classification guidelines and in following report generation protocols to meet requirements for quality and turnaround time. The Clinical Genomic Scientist II has an understanding of genomic technologies and may assist in technical troubleshooting as needed. Additional responsibilities as designated by the Supervisor/Manager, which may include providing input in the development of guidelines and/or assisting with training of new Clinical Genomic Scientists.

Essential Functions:

Attend and provide input at trainings regarding reporting protocols applicable to the specific position or specialty

Leverage awareness of current process and systems to provide suggestions for improvements

Maintain expertise in clinical and technical aspects relevant to the specific position

Interpret clinical diagnostic testing results in accordance with established SOPs

Variant assessment and classification

Independently draft clear, accurate clinical testing results

Effective communication and collaboration with team colleagues; ability to regularly provide input and receive feedback in team discussions

Other duties as assigned

Qualifications:

Ph.D. in Molecular Biology, Genetics, or related scientific field or MS in Genetic Counseling from an accredited institution or MS in Genetics, Molecular Biology, Biochemistry, or other similar field of study

2+ years of experience in at least one of the following areas: primary genetics literature review, variant classification, genetic evidence summary writing, clinical report drafting, or sequencing result analysis

Thorough and ongoing knowledge of current theories and principles of human genetics

Ability to understand and evaluate genetic data and literature

Excellent written and verbal communication skills Enthusiasm and ability to work in and contribute to a fast-paced, highly collaborative environment

Familiarity with diagnostic testing methodologies, including next-generation and Sanger sequencing, microarray, and MLPA

Maintain expertise in clinical and technical aspects related to the specific position and communicate with other internal departments to resolve/ escalate issues as appropriate

Must possess strong working knowledge of human genetics and diagnostic genetic testing concept

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