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Variant Scientist Jobs (NOW HIRING)

Cook Children's

Bioinformatician

Fort Worth, TX · On-site

This position will collaborate closely with Cook Children's variant scientists, genetic counselors, clinicians, data scientists, and computational teams. Experience * 2 years experience in genomic ...

Variant Bio

Senior Security Engineer

Seattle, WA · On-site

$184K - $241K/yr

ABOUT THE ROLE At Variant Bio, protecting the data entrusted to us by our partner communities is ... S. in Computer Science or related field, or equivalent experience. * 8+ years designing and ...

Variant Bio

Executive Administrator

Seattle, WA · On-site

Variant Bio is developing life-saving therapies by studying the genes of people with exceptional ... Experience at an early-stage biotech, life sciences, or clinical-stage company. * Background ...

Ambry Genetics

$110K - $114K/yr

The Clinical Genomic Scientist II is highly proficient in variant classification guidelines and in following report generation protocols to meet requirements for quality and turnaround time. The ...

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How much do variant scientist jobs pay per hour?

As of Jul 14, 2026, the average hourly pay for variant scientist in the United States is $47.05, according to ZipRecruiter salary data. Most workers in this role earn between $34.13 and $59.62 per hour, depending on experience, location, and employer.

What Does a Variant Scientist Do?

As a variant scientist, you work for a research laboratory in a university or a medical facility to test and study variations of genes and the effects they have on human development. As part of your duties, you aid in the development of new tests to discover gene abnormalities, perform analysis on patient samples to identify possible mutations, and record your findings to assist in scientific research. You also have heavy reporting responsibilities that may require in-depth computer and writing skills, the ability to analyze data, and strong attention to detail. In this role, you may cater to a specific health field, like pediatrics or oncology.

What are some common challenges faced by Variant Scientists in interpreting genetic data, and how are these typically addressed within a team?

Variant Scientists often encounter challenges such as distinguishing between benign and pathogenic variants, managing large volumes of sequencing data, and staying updated with rapidly evolving genetic databases. These challenges are typically addressed by collaborating closely with bioinformaticians, clinical geneticists, and laboratory personnel to review findings and validate interpretations. Regular team meetings, use of standardized classification guidelines like ACMG, and leveraging advanced software tools help ensure accurate and consistent variant analysis.

What are Variant Scientists?

Variant Scientists are professionals who analyze genetic variants—differences in DNA sequences—to determine their significance in health and disease. They interpret genomic data, often from whole-genome or exome sequencing, to assess whether specific variants may cause or contribute to medical conditions. Their work is crucial in clinical genetics, precision medicine, and biomedical research, helping guide patient diagnosis and treatment. Variant Scientists collaborate with clinicians, bioinformaticians, and laboratory personnel to provide accurate and actionable genetic insights.

What are the key skills and qualifications needed to thrive as a Variant Scientist, and why are they important?

To thrive as a Variant Scientist, you need a solid background in genetics, molecular biology, and bioinformatics, typically supported by an advanced degree such as a PhD or MSc in a related field. Familiarity with next-generation sequencing (NGS) platforms, variant annotation tools, and data analysis software like GATK or ANNOVAR is essential. Strong analytical thinking, attention to detail, and effective communication skills help you interpret complex genetic data and collaborate with multidisciplinary teams. These skills ensure accurate variant interpretation, drive discoveries, and support precision medicine initiatives.
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Variant Scientist jobs near you
Infographic showing various Variant Scientist job openings in the United States as of July 2026, with employment types broken down into 1% As Needed, 91% Full Time, 5% Part Time, and 3% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $97,868 per year, or $47.1 per hour.
Bioinformatician

Bioinformatician

Cook Children's

Fort Worth, TX • On-site

Full-time

Posted 3 days ago

Cook Children's Health Care System rating

7.7

Company rating: 7.7 out of 10

Based on 74 frontline employees who took The Breakroom Quiz

157th of 884 rated healthcare providers

Job description

Location:

Medical Center Office Building (901 7th Ave)

Department:

Pediatric Precision Health Program

Shift:

First Shift (United States of America)

Standard Weekly Hours:

40

Summary:

The Bioinformatician will support the Cook Children's precision health and precision medicine research ecosystem by developing and maintaining analytical pipelines for genomic data, performing variant annotation and interpretation, building tools for clinical decision support, and advancing data integration across genomics, clinical phenotypes, and functional datasets. This role supports precision clinics, genome-informed care, research, and AI-enabled clinical workflows. This position will collaborate closely with Cook Children's variant scientists, genetic counselors, clinicians, data scientists, and computational teams.

Experience

  • 2 years experience in genomic data processing, variant annotation, or large-scale data analysis

  • Demonstrated proficiency in R and/or Python, SQL, Linux/Unix environments, and common bioinformatics workflows

Education

  • Master's degree in Bioinformatics, Computational Biology, Genetics, Data Science, Computer Science, or related field

About Us:

Cook Children's Health Care System

Cook Children's Health Care System offers a unique approach to caring for children because we are one of the country's leading integrated pediatric health care delivery organizations. Patients benefit from the integrated system because it allows Cook Children's to use all of its resources to treat a patient and allows for easy communication between the various companies by physicians with a focus on caring for children and adolescents.

Cook Children's is an equal opportunity employer. As such, Cook Children's offers equal employment opportunities without regard to race, color, religion, sex, age, national origin, physical or mental disability, pregnancy, protected veteran status, genetic information, or any other protected class in accordance with applicable federal laws. These opportunities include terms, conditions and privileges of employment, including but not limited to hiring, job placement, training, compensation, discipline, advancement and termination.

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About Cook Children's Health Care System

Sourced by ZipRecruiter

Cook Children's Health Care System, based in Fort Worth, Texas, operates in the healthcare industry with a primary focus on pediatric health services. Established in 1918, the system has been committed to improving the health of children through the prevention and treatment of childhood diseases. This integrated pediatric healthcare system includes a medical center, physician network, home health company, research institute, and a health plan. At the core of its operations is the mission to 'Improve the Health of Every Child' in its community, reflecting its commitment to providing quality care, research, education, and prevention and wellness services.

Industry

Health care and social assistance

Company size

5,001 - 10,000 Employees

Headquarters location

Fort Worth, TX, US

Year founded

1918

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