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Variant Scientist Jobs in Arizona (NOW HIRING)

Caris Life Sciences

Manager - Bioinformatics

Tempe, AZ · On-site

Backed by cutting-edge molecular science and AI, we ask ourselves every day: "What would I do if ... Support end-to-end genomic data analysis, including quality control, alignment, variant calling ...

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Variant Scientist information

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$17

$45

$78

How much do variant scientist jobs pay per hour?

As of Jul 26, 2026, the average hourly pay for variant scientist in Arizona is $45.68, according to ZipRecruiter salary data. Most workers in this role earn between $33.14 and $57.88 per hour, depending on experience, location, and employer.

What Does a Variant Scientist Do?

As a variant scientist, you work for a research laboratory in a university or a medical facility to test and study variations of genes and the effects they have on human development. As part of your duties, you aid in the development of new tests to discover gene abnormalities, perform analysis on patient samples to identify possible mutations, and record your findings to assist in scientific research. You also have heavy reporting responsibilities that may require in-depth computer and writing skills, the ability to analyze data, and strong attention to detail. In this role, you may cater to a specific health field, like pediatrics or oncology.

What are some common challenges faced by Variant Scientists in interpreting genetic data, and how are these typically addressed within a team?

Variant Scientists often encounter challenges such as distinguishing between benign and pathogenic variants, managing large volumes of sequencing data, and staying updated with rapidly evolving genetic databases. These challenges are typically addressed by collaborating closely with bioinformaticians, clinical geneticists, and laboratory personnel to review findings and validate interpretations. Regular team meetings, use of standardized classification guidelines like ACMG, and leveraging advanced software tools help ensure accurate and consistent variant analysis.

What are Variant Scientists?

Variant Scientists are professionals who analyze genetic variants—differences in DNA sequences—to determine their significance in health and disease. They interpret genomic data, often from whole-genome or exome sequencing, to assess whether specific variants may cause or contribute to medical conditions. Their work is crucial in clinical genetics, precision medicine, and biomedical research, helping guide patient diagnosis and treatment. Variant Scientists collaborate with clinicians, bioinformaticians, and laboratory personnel to provide accurate and actionable genetic insights.

What are the key skills and qualifications needed to thrive as a Variant Scientist, and why are they important?

To thrive as a Variant Scientist, you need a solid background in genetics, molecular biology, and bioinformatics, typically supported by an advanced degree such as a PhD or MSc in a related field. Familiarity with next-generation sequencing (NGS) platforms, variant annotation tools, and data analysis software like GATK or ANNOVAR is essential. Strong analytical thinking, attention to detail, and effective communication skills help you interpret complex genetic data and collaborate with multidisciplinary teams. These skills ensure accurate variant interpretation, drive discoveries, and support precision medicine initiatives.
More about Variant Scientist jobs
What are the most commonly searched types of Variant Scientist jobs in Arizona? The most popular types of Variant Scientist jobs in Arizona are:
What are popular job titles related to Variant Scientist jobs in Arizona? For Variant Scientist jobs in Arizona, the most frequently searched job titles are:
What job categories do people searching Variant Scientist jobs in Arizona look for? The top searched job categories for Variant Scientist jobs in Arizona are:
Variant Scientist jobs near you
Infographic showing various Variant Scientist job openings in Arizona as of July 2026, with employment types broken down into 1% As Needed, 93% Full Time, 4% Part Time, and 2% Contract. Highlights an 90% Physical, 4% Hybrid, and 6% Remote job distribution, with an average salary of $95,018 per year, or $45.7 per hour.
Clinical Genomics Scientist

Clinical Genomics Scientist

Phoenix Children's Hospital

Phoenix, AZ • On-site

Full-time

Posted 7 days ago

Job description

Position Details
Department: PCH-MAIN | Lab Genomics
Location: Phoenix
Shift: Mon-Fri, Shifts Vary, 8am-5pm
Category: Laboratory/Pathology
Posting #: 1027389
Employee Type: Full-Time
Position Summary
The Clinical Genomics Scientist plays a critical role in variant interpretation, classification, and reporting to support clinical genomic testing. This position provides high-level scientific expertise in the analysis of genetic testing data including next-generation sequencing (NGS) such including NGS panels, whole exome sequencing (WES), and whole genome sequencing (WGS). The Clinical Genomics Scientist will work closely with Clinical Genomics physician leadership to ensure high-quality, clinically reliable genomic results and to advance the adoption of cutting-edge innovations in genomic testing. Responsibilities include supporting the director's efforts in test development, implementation, optimization, and validation, as well as contributing to the growth and development of Phoenix Children's Clinical Genomics Laboratory. This is a laboratory staff position with accountability to laboratory leadership for operational and administrative matters and to physician leadership for all clinical, scientific, and laboratory interpretation activities. The Clinical Genomics Scientist is expected to work within the priorities, direction, and defined scope established by laboratory leadership. Activities or commitments outside the defined scope of this role require advanced approval from laboratory leadership.
Position Duties
  • Variant Interpretation and Reporting
    Interpret and classify genetic variants for all assays including NGS assays (WES, WGS, targeted panels); apply ACMG/AMP guidelines and prepare evidence-based summaries.
  • Data Review and Quality Control
    Review sequencing data to identify artifacts and ensure high-confidence variant calls; maintain documentation and compliance.
  • Validation and Implementation of New Technologies
    Support validation and launch of new NGS and bioinformatics platforms, assuring accuracy and efficiency.
  • Clinical Reporting Collaboration
    Collaborate with laboratory medical director(s), genetic counselor(s) to prepare and finalize clinical reports for patient care.
  • Workflow Development and Optimization
    Work with bioinformatics and technical teams to troubleshoot pipelines and optimize variant analysis performance.
  • Gene and Variant Curation
    Contribute to curation initiatives and update panel content to enhance clinical relevance and data consistency.
  • Quality Assurance and Compliance
    Participate in internal audits, proficiency testing, and ongoing QC processes to uphold CLIA/CAP standards.
  • Training and Mentorship
    Train and mentor technologists, fellows, and bioinformaticians in variant interpretation and workflow best practices.
  • Scientific Engagement
    Stay current on emerging genomic technologies and present findings at internal meetings or conferences.
  • Performs miscellaneous job related duties as requested.

Phoenix Children's Mission, Vision, & Values
Mission
To advance hope, healing and the best healthcare for children and their families
Vision
Phoenix Children's will be the leading pediatric health system in the Southwest, nationally recognized for exceptional care, innovative research and advanced medical education.
We realize this vision by:
  • Offering the most comprehensive care across ages, communities and specialties
  • Investing in innovative research, including emerging treatments, tools and technologies
  • Advancing education and training to shape the next generation of clinical leaders
  • Advocating for the health and well-being of children and families
Values
  • We place children and families at the center of all we do
  • We deliver exceptional care, every day and in every way
  • We collaborate with colleagues, partners and communities to amplify our impact
  • We set the standards of pediatric healthcare today, and innovate for the future
  • We are accountable for making the highest quality care accessible and affordable
Phoenix Children's Hospital logo

About Phoenix Children's Hospital

Sourced by ZipRecruiter

Phoenix Children's Hospital, located in Phoenix, AZ, is a prominent establishment within the healthcare industry. Known for its commitment to pediatric healthcare, the hospital provides a vast range of services catering to the unique health needs of children. Originally founded in 1983, Phoenix Children's Hospital prides itself on being one of the largest and most respected children's hospitals in the country. Guided by its mission–"to provide hope, healing and the best healthcare for children and their families"–the hospital holds strong on its core values of family-centered care, excellence in clinical care, innovation, and stewardship.

Industry

Health care and social assistance

Company size

1,001 - 5,000 Employees

Headquarters location

Phoenix, AZ, US

Year founded

1983

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