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Variant Scientist Jobs in Chicago, IL (NOW HIRING)

Belay Diagnostics

Clinical Genomics Analyst

Chicago, IL · On-site

$80K - $90K/yr

Evaluate variant function, potential clinical impact and genotype-phenotype relationships using scientific literature and available genomic tools * Write clear, communicable reports based on test ...

MyOme

Clinical Genomic Specialist

Chicago, IL · On-site

$110K - $140K/yr

Our team is composed of seasoned entrepreneurs, scientists, and operators, and we're backed by top ... Perform variant assessment and classification across proactive and rare disease whole genome ...

All JobsVariant Scientist JobsVariant Scientist Jobs in Chicago, IL

Variant Scientist information

See Chicago, IL salary details

$18

$48

$83

How much do variant scientist jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for variant scientist in Chicago, IL is $48.29, according to ZipRecruiter salary data. Most workers in this role earn between $35.04 and $61.19 per hour, depending on experience, location, and employer.

What is a variant scientist?

Variant Scientists are professionals who analyze genetic variants—differences in DNA sequences—to determine their significance in health and disease. They interpret genomic data, often from whole-genome or exome sequencing, to assess whether specific variants may cause or contribute to medical conditions. Their work is crucial in clinical genetics, precision medicine, and biomedical research, helping guide patient diagnosis and treatment. Variant Scientists collaborate with clinicians, bioinformaticians, and laboratory personnel to provide accurate and actionable genetic insights.

What does a variant scientist do?

As a variant scientist, you work for a research laboratory in a university or a medical facility to test and study variations of genes and the effects they have on human development. As part of your duties, you aid in the development of new tests to discover gene abnormalities, perform analysis on patient samples to identify possible mutations, and record your findings to assist in scientific research. You also have heavy reporting responsibilities that may require in-depth computer and writing skills, the ability to analyze data, and strong attention to detail. In this role, you may cater to a specific health field, like pediatrics or oncology.

What are the key skills and qualifications needed to thrive as a variant scientist, and why are they important?

To thrive as a Variant Scientist, you need a solid background in genetics, molecular biology, and bioinformatics, typically supported by an advanced degree such as a PhD or MSc in a related field. Familiarity with next-generation sequencing (NGS) platforms, variant annotation tools, and data analysis software like GATK or ANNOVAR is essential. Strong analytical thinking, attention to detail, and effective communication skills help you interpret complex genetic data and collaborate with multidisciplinary teams. These skills ensure accurate variant interpretation, drive discoveries, and support precision medicine initiatives.

What are some common challenges faced by variant scientists in interpreting genetic data, and how are these typically addressed within a team?

Variant Scientists often encounter challenges such as distinguishing between benign and pathogenic variants, managing large volumes of sequencing data, and staying updated with rapidly evolving genetic databases. These challenges are typically addressed by collaborating closely with bioinformaticians, clinical geneticists, and laboratory personnel to review findings and validate interpretations. Regular team meetings, use of standardized classification guidelines like ACMG, and leveraging advanced software tools help ensure accurate and consistent variant analysis.
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For Variant Scientist jobs in Chicago, IL, the most frequently searched job titles are:

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Cities near Chicago, IL with the most Variant Scientist job openings:

Variant Scientist jobs near you
Infographic showing various Variant Scientist job openings in Chicago, IL as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $100,453 per year, or $48.3 per hour.

Bioinformatics Scientist

Discover International

Mundelein, IL • On-site

Other

Posted 7 days ago

Job description

Bioinformatics Scientist | South San Francisco, CA (Remote Flex)


I'm working on a retained search for a high-growth DNA sequencing company that's quietly become one of the most-used platforms in modern biotech — Nobel laureates, top-tier startups, and DIY biohackers all run their science through this platform daily.


They're building something genuinely different: a team that moves at software speed inside a biology world. If you've ever been frustrated by how slow biotech moves, this is for you.


The Role

This isn't a "maintain the pipeline" job. You'll be architecting production-grade bioinformatics workflows that process thousands of samples per day, developing novel algorithms that turn raw sequencing data into fast, intuitive insights, and translating that science directly into user-facing experiences. You'll also mentor teammates and help set the technical direction of the function.


What They're Looking For

  • PhD in Bioinformatics, CS, Statistics, Physics or similar — with 3+ years building production pipelines
  • Deep domain expertise in at least one of: microbial genomics (assembly/metagenomics), variant calling/large-scale genomics, or bulk/single-cell RNA-seq
  • Production experience with Nextflow or Snakemake, including cloud deployments
  • Strong Python (numpy, pandas, biopython, Jupyter) and solid Linux/Git fundamentals
  • Bonus: a track record of publishing or developing novel bioinformatics algorithms


Why It's Worth a Conversation

✅ Mission-driven accelerating life-saving research globally

✅ Small, elite team real ownership and impact from day one

✅ Fast-moving culture that rewards intellectual curiosity


Contact Sam Shinner at Discover International to apply


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About Discover International

Sourced by ZipRecruiter

In the ever changing and complex work environment Life Science Organisations face today, a flexible workforce is key to agility and performance. Working in partnership we review your requirements, challenges and goals, and design a tailored Discover Consulting solution that delivers the results you need. Discover Consulting provides a tailored, trusted, end-to-end consultancy service and the best independent contractors in the market.

Industry

Recruiting and staffing services

Company size

51 - 200 Employees

Headquarters location

Miami, FL, US

Social media

Instagram

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