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Upstream Bio Jobs (NOW HIRING)

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... upstream processing equipment. Specific Duties Include: * Serve as a valuable member of the ... Our biopolymers are bio-based and made from renewable resources that are biodegradable and ...

Director/ Senior Director, Regulatory CMC

Boston, MA · On-site

$163K - $215K/yr

... upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing ... Vor Bio is seeking an exceptional and highly motivated CMC leader Director/Sr Director Regulatory ...

Bio Manufacturing Operator

Elwood, KS · On-site

$17 - $20.25/hr

Execute and monitor core mAb manufacturing processes (media/buffer prep, upstream/downstream processing, formulation, fill/finish, secondary packaging). * Maintain cGMP compliance in a regulated ...

Perform operations in a bio-safety cabinet using aseptic technique and maintain asepsis of all closed container sterile processes. * Perform upstream production activities including thawing of cell ...

Perform operations in a bio-safety cabinet using aseptic technique and maintain asepsis of all closed container sterile processes. * Perform upstream production activities including thawing of cell ...

... bio-chemicals and bio-plastics for Industrial Biotechnology. Apply the knowledge of the ... Assists customers through the entire upstream process, from initial screening up to full-scale ...

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Upstream Bio information

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$29K

$59.8K

$109K

How much do upstream bio jobs pay per year?

As of Aug 22, 2026, the average yearly pay for upstream bio in the United States is $59,773.00, according to ZipRecruiter salary data. Most workers in this role earn between $42,500.00 and $70,000.00 per year, depending on experience, location, and employer.

What is an upstream bio scientist?

An Upstream Bio scientist focuses on the early stages of bioprocessing, specifically cultivating and optimizing the growth of cells or microorganisms to produce desired biological products such as proteins or antibodies. Their work includes developing cell lines, optimizing culture conditions, scaling up processes from laboratory to industrial scale, and ensuring high yields and quality. Upstream Bio scientists play a critical role in biotechnology, pharmaceuticals, and biomanufacturing, working closely with downstream processing teams to ensure efficient and successful product development.

What does an upstream bioprocessing scientist do?

Upstream bioprocessing professionals typically focus on cultivating and optimizing cell cultures to produce biological products such as proteins or vaccines. Daily tasks often include preparing media, monitoring bioreactor parameters, sampling and analyzing cell growth, and troubleshooting process deviations. Collaboration with downstream processing teams and quality control is frequent to ensure seamless handoff and product quality. Additionally, maintaining detailed records and contributing to process improvement initiatives are key parts of the role.

What skills and qualifications are needed to thrive as an upstream bioprocessing scientist?

To thrive as an Upstream Bioprocessing Scientist, you need a strong background in biology, chemistry, and biochemical engineering, typically supported by a degree in a related field. Experience with bioreactors, cell culture systems, process optimization, and familiarity with GMP regulations and analytical tools are essential. Problem-solving, teamwork, and attention to detail are crucial soft skills for excelling in complex laboratory environments. These competencies ensure efficient development and scaling of biologics production, directly impacting product quality and regulatory compliance.

What is the difference between Upstream Bio vs Downstream Bio?

AspectUpstream BioDownstream Bio
Focus AreaEarly-stage research, target discovery, molecular biologyProduct development, manufacturing, formulation
Required CredentialsBiochemistry, molecular biology, cell biology degreesBiochemistry, pharmaceutical sciences, chemical engineering degrees
Work EnvironmentResearch labs, biotech startups, academic collaborationsManufacturing facilities, quality control labs, biotech companies

Upstream Bio primarily involves early research and target identification, while Downstream Bio focuses on product development and manufacturing processes. Both roles require strong backgrounds in biology or chemistry, but they differ in their specific focus areas and work environments. Understanding these differences helps professionals choose the right career path within the biotech industry.

More about Upstream Bio jobs

What cities are hiring for Upstream Bio jobs?

Cities with the most Upstream Bio job openings:

What states have the most Upstream Bio jobs?

States with the most job openings for Upstream Bio jobs include:

Infographic showing various Upstream Bio job openings in the United States as of August 2026, with employment types broken down into 2% As Needed, 83% Full Time, 12% Part Time, and 3% Contract. Highlights an 95% Physical, 2% Hybrid, and 3% Remote job distribution, with an average salary of $59,773 per year, or $28.7 per hour.

Bioprocessing Manufacturing Technician

RWDC Industries

Athens, GA • On-site

$45K - $46K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 3 days ago

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Job description

Immediate opening for a Bioprocess Technician operating seed and production scale bioreactors and upstream processing equipment.

Specific Duties Include:

  • Serve as a valuable member of the Bioprocess and Process Teams, working effectively to meet goals, objectives, and complete tasks to achieve desired results.
  • Operate bioreactors to support fermentation process development and production activities, which includes cleaning, sterilizing, addition of media components, reactor sampling, and routine maintenance.
  • Support downstream processing by assisting with running separator equipment, chemical additions, and cleaning processes.
  • Provide timely and accurate verbal and written communication to team members and management.
  • Work with other team members to prioritize tasks/assignments and make recommendations to maximize efficiency/productivity based on production and departmental needs.
  • Promote and contribute to a safe working environment.
  • Successful candidates must be willing to work, day and night shifts.

Skills Required:

  • Must possess solid problem-solving, interpersonal communication, and team-based skills
  • Ability to follow Standard Operating Procedures (SOPs)
  • Must be computer proficient and have good working knowledge of Microsoft Office
  • Basic maintenance skills and good mechanical aptitude
  • Ability to multitask and prioritize workload
  • Must be willing and able to work in a process environment which requires frequent standing, walking upstairs, and lifting moderate weights (up to 50 lbs)
  • Strong desire to change the world

Preferred:

  • Demonstrated experience/knowledge working in a bioprocessing/biotechnology facility.
  • Understand basic laboratory protocols/procedures, including basic bioprocessing and fermentation techniques, major unit operations and aseptic techniques.

Education:

· Associate degree and/or Equivalent work experience will be considered

Company Description

We are a growing biotechnology company in Athens, Georgia. We manufacture bio-based polymers with a goal of replacing single-use petroleum-based plastics. Our biopolymers are bio-based and made from renewable resources that are biodegradable and compostable.