It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution of a trial and ultimately plays a big role in a new drug or device ...
It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution of a trial and ultimately plays a big role in a new drug or device ...
It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution of a trial and ultimately plays a big role in a new drug or device ...
It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution of a trial and ultimately plays a big role in a new drug or device ...
Clinical Trial Associate- Trial Master File (TMF)
Cincinnati, OH · On-site
$32.25 - $44/hr
It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution of a trial and ultimately plays a big role in a new drug or device ...
Clinical Trial Associate- Trial Master File (TMF)
Cincinnati, OH · On-site
$32.25 - $44/hr
It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution of a trial and ultimately plays a big role in a new drug or device ...
Junior Documentation Associate- Trial Master File (TMF)
Cincinnati, OH · On-site
$32.25 - $44/hr
It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution of a trial and ultimately plays a big role in a new drug or device ...
Junior Documentation Associate- Trial Master File (TMF)
Cincinnati, OH · On-site
$32.25 - $44/hr
It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution of a trial and ultimately plays a big role in a new drug or device ...
Overseas Trial Management File (TMF) management and reviews TMF documents as necessary * Manage relationships with external vendors and contractors, ensuring that their deliverables meet study ...
Quick apply
Overseas Trial Management File (TMF) management and reviews TMF documents as necessary * Manage relationships with external vendors and contractors, ensuring that their deliverables meet study ...
Assists in TMF management and manages TMF reviews as needed. * Prepares for and participates in third-party audits and FDA inspections. * Complies with and ensures team compliance with ICH GCP ...
Assists in TMF management and manages TMF reviews as needed. * Prepares for and participates in third-party audits and FDA inspections. * Complies with and ensures team compliance with ICH GCP ...
Loan Assistant
Georgetown, TX · On-site
$34K - $43K/yr
Demonstrate core values as defined by TMF and Wesleyan Impact Partners when interacting with ... Perform any additional duties, tasks, and projects as assigned by management. Requirements * High ...
Loan Assistant
Georgetown, TX · On-site
$34K - $43K/yr
Demonstrate core values as defined by TMF and Wesleyan Impact Partners when interacting with ... Perform any additional duties, tasks, and projects as assigned by management. Requirements * High ...
Associate Director Trial Master File
Santa Rosa, CA · On-site
$36.75 - $50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Santa Rosa, CA · On-site
$36.75 - $50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Manager, Clinical Research
Paramus, NJ · On-site
$110K - $135K/yr
TMF oversight review during study conduct and TMF management during study closeout. * Support creating and maintaining clinical SOPs as part of global QMS. * Perform administrative tasks (e.g ...
Quick apply
Manager, Clinical Research
Paramus, NJ · On-site
$110K - $135K/yr
TMF oversight review during study conduct and TMF management during study closeout. * Support creating and maintaining clinical SOPs as part of global QMS. * Perform administrative tasks (e.g ...
Clinical Operations Associate (Pool)
CA · Remote
$70K - $80K/yr
TMF Management * Perform QC review of TMF documents. * File documents per TMF Reference Model. * Identify gaps, inconsistencies, and missing documentation. * Support audit and inspection readiness.
Clinical Operations Associate (Pool)
CA · Remote
$70K - $80K/yr
TMF Management * Perform QC review of TMF documents. * File documents per TMF Reference Model. * Identify gaps, inconsistencies, and missing documentation. * Support audit and inspection readiness.
Associate Director Trial Master File
Fremont, CA · On-site
$36.75 - $50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Fremont, CA · On-site
$36.75 - $50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
San Jose, CA · On-site
$39.25 - $53.50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
San Jose, CA · On-site
$39.25 - $53.50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
San Francisco, CA · On-site
$39.50 - $54/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
San Francisco, CA · On-site
$39.50 - $54/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Santa Clara, CA · On-site
$39 - $53.25/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Santa Clara, CA · On-site
$39 - $53.25/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Alameda, CA · On-site
$38.75 - $53/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Alameda, CA · On-site
$38.75 - $53/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Hayward, CA · On-site
$38.50 - $52.50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Hayward, CA · On-site
$38.50 - $52.50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
This role coordinates site outreach, study and site start-up activities, IRB submissions, and ongoing electronic Trial Master File (TMF) management. A typical day includes collecting and reviewing ...
This role coordinates site outreach, study and site start-up activities, IRB submissions, and ongoing electronic Trial Master File (TMF) management. A typical day includes collecting and reviewing ...
Associate Director Trial Master File
Sonoma, CA · On-site
$37.50 - $51.25/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Sonoma, CA · On-site
$37.50 - $51.25/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Sunnyvale, CA · On-site
$39.75 - $54.50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
Sunnyvale, CA · On-site
$39.75 - $54.50/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
San Mateo, CA · On-site
$38.25 - $52/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Associate Director Trial Master File
San Mateo, CA · On-site
$38.25 - $52/hr
Drive risk-based TMF oversight, issue management, and CAPA development related to TMF quality or compliance findings. * Partner cross-functionally with Clinical Operations, Quality, Regulatory ...
Tmf Manager information
See salary details
$28.85 - $34.97
4% of jobs
$34.97 - $41.08
6% of jobs
$41.08 - $47.20
7% of jobs
$51.79 is the 25th percentile. Wages below this are outliers.
$47.20 - $53.32
9% of jobs
$53.32 - $59.44
15% of jobs
The median wage is $62.14 / hr.
$59.44 - $65.56
18% of jobs
$69.92 is the 75th percentile. Wages above this are outliers.
$65.56 - $71.68
21% of jobs
$71.68 - $77.80
7% of jobs
$77.80 - $83.92
6% of jobs
$83.92 - $90.03
3% of jobs
$90.03 - $96.15
2% of jobs
$28
$62
$96
How much do tmf manager jobs pay per hour?
As of Jun 27, 2026, the average hourly pay for tmf manager in the United States is $62.52, according to ZipRecruiter salary data. Most workers in this role earn between $50.72 and $70.43 per hour, depending on experience, location, and employer.
What are some typical challenges a TMF Manager might face in their role?
TMF Managers often encounter challenges such as ensuring consistent TMF document quality across multiple studies, meeting tight regulatory submission deadlines, and facilitating communication among global project teams. Keeping the TMF up to date and audit-ready requires strong organizational skills and proactive problem-solving, as studies can involve large volumes of documentation and frequent protocol amendments. Effective TMF Managers routinely collaborate with clinical, regulatory, and quality assurance teams to ensure document accuracy and regulatory compliance. Overcoming these challenges is key to maintaining smooth clinical trial operations and supporting successful regulatory inspections.
What are the key skills and qualifications needed to thrive in the Tmf Manager position, and why are they important?
To excel as a TMF Manager (Trial Master File Manager), you need a solid understanding of clinical trial documentation, GCP (Good Clinical Practice) guidelines, and regulatory requirements—typically supported by a degree in life sciences or a related field. Familiarity with electronic TMF (eTMF) systems, document management software, and relevant industry certifications such as RAC or DIA TMF certificates is important. Exceptional attention to detail, organizational skills, and the ability to communicate effectively across cross-functional teams distinguish top TMF Managers. These competencies are essential for ensuring the integrity, completeness, and audit-readiness of clinical trial documentation throughout the study lifecycle.
What is a TMF Manager job?
A TMF (Trial Master File) Manager is responsible for overseeing the management, maintenance, and compliance of clinical trial documentation. They ensure that the TMF is accurate, complete, and inspection-ready in accordance with regulatory requirements, such as ICH-GCP and FDA guidelines. TMF Managers collaborate with clinical teams, quality assurance, and regulatory authorities to support audit and inspection activities. Their role is critical in ensuring data integrity and regulatory compliance throughout the clinical trial lifecycle.
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$32.25 - $44/hr
Other
Medical, PTO
Posted 19 days ago
Medpace rating
8.4
Based on 8 frontline employees who took The Breakroom Quiz
15th of 58 rated research
Job description
Job Summary
We are currently hiring individuals seeking an exciting career in clinical research, managing our Trial Master File. The Trial Master File (TMF) is a collection of documents that stores all data and research collected on a given trial. The TMF allows us to conduct a clinical trial and ensures data integrity. It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution of a trial and ultimately plays a big role in a new drug or device receiving approval by the FDA. In this position, you will be working with a highly experienced team of other administrators and clinical research professionals that can help you grow your skillset while working for a growing and developing company. *This position is fully office-based in Cincinnati, OH.
ResponsibilitiesThe Documentation Specialist supports TMF oversight for a trial by ensuring documents meet established quality standards. This position involves both independent and computer-based work, as well as opportunity for communication and collaboration with trial teams.
- Manage electronic filing system for trial documentation;
- Track, maintain, and perform quality check of electronic documents;
- Communicate with internal associates globally regarding errors in trial documents; and
- Prepare documents for shipment.
- Associates degree, or equivalent required;
- Bachelor's degree preferred;
- Some experience in document administration;
- High attention to detail;
- Excellent organizational skills
- Strong written and verbal communication skills; and
- Knowledge of MS Office.
Medpace is a full-service clinical contract research organization (CRO). We provide Phase I-IV clinical development services to the biotechnology, pharmaceutical and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics through its scientific and disciplined approach. We leverage local regulatory and therapeutic expertise across all major areas including oncology, cardiology, metabolic disease, endocrinology, central nervous system, anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, employing more than 6,000 people across 40+ countries.
Why Medpace?People. Purpose. Passion. Make a Difference Tomorrow. Join Us Today.
The work we've done over the past 30+ years has positively impacted the lives of countless patients and families who face hundreds of diseases across all key therapeutic areas. The work we do today will improve the lives of people living with illness and disease in the future.
Cincinnati Perks
- Flexible work environment
- Competitive PTO packages, starting at 20+ days
- Competitive compensation and benefits package
- Company-sponsored employee appreciation events
- Employee health and wellness initiatives
- Community involvement with local nonprofit organizations
- Discounts on local sports games, fitness gyms and attractions
- Modern, ecofriendly campus with an on-site fitness center
- Structured career paths with opportunities for professional growth
- Discounted tuition for UC online programs
Awards
Named a Top Workplace in 2024 by The Cincinnati Enquirer
- Recognized by Forbes as one of America's Most Successful Midsize Companies in 2021, 2022, 2023 and 2024
- Continually recognized with CRO Leadership Awards from Life Science Leader magazine based on expertise, quality, capabilities, reliability, and compatibility
What to Expect Next
A Medpace team member will review your qualifications and, if interested, you will be contacted with details for next steps.
Employment Type: OTHER
About Medpace
Sourced by ZipRecruiter
Medpace is a globally recognized clinicial contract research organization (CRO) based in Cincinnati, OH, in the United States. Established in 1992, it operates in the healthcare sector, providing scientifically-driven outsourcing solutions for the development of drugs and medical devices. It offers comprehensive services like full-service clinical development services, regulatory affairs management, clinical pharmacology, data management, statistical analysis, and medical writing. By applying a scientifically-driven, therapeutically-focused, and patient-centric approach, Medpace's mission is to accelerate the global development of safe and effective medical therapies.
Industry
Medical equipment and supplies manufacturing
Company size
1,001 - 5,000 Employees
Headquarters location
Cincinnati, OH, US
Year founded
1992