ZipRecruiter

Log In

1

Tmf Jobs (NOW HIRING)

Systimmune

Associate Director, TMF Operations

Princeton, NJ · On-site

$140K - $180K/yr

Beyond TMF responsibilities, this position oversees Clinical Operations reporting, metrics, KPIs, and analytics. The role involves collaborating with senior leaders and key stakeholders to establish ...

Medpace, Inc.

Entry-Level TMF Administrator

Cincinnati, OH · On-site

$32.25 - $44/hr

The TMF allows us to conduct a clinical trial and ensures data integrity. It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution ...

Medpace, Inc.

Entry-Level TMF Administrator

Cincinnati, OH · On-site

$32.25 - $44/hr

The TMF allows us to conduct a clinical trial and ensures data integrity. It is an integral tool and helps teams manage trials more effectively. TMF oversight is important to the successful execution ...

Jobgether

Our partner is looking for a Senior Associate II, TMF Operations based in Netherlands. This is an opportunity to join a global clinical research environment where your expertise helps ensure the ...

TMF Group

Client Director

Miami, NM · On-site

About TMF TMF Group is a leading provider of administrative services, helping clients invest and operate safely around the world. As we're a global company with 12,000+ colleagues based in over 125 ...

next page

Showing results 1-20

All JobsTmf Jobs

Tmf information

See salary details

$17

$39

$70

How much do tmf jobs pay per hour?

As of Jul 14, 2026, the average hourly pay for tmf in the United States is $39.99, according to ZipRecruiter salary data. Most workers in this role earn between $32.21 and $43.99 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Tmf position, and why are they important?

To thrive as a TMF (Trial Master File) Specialist, you need a solid understanding of clinical trial documentation, regulatory guidelines (such as ICH-GCP), and strong organizational skills, typically supported by experience in clinical research or a related life sciences field. Proficiency with electronic Trial Master File (eTMF) systems, document management software, and sometimes certifications like DIA TMF or clinical research certification are commonly required. Attention to detail, effective communication, and the ability to manage deadlines are important soft skills in this role. These competencies ensure regulatory compliance, efficient document retrieval, and successful clinical trial audits.

What is a TMF job?

A TMF (Trial Master File) job typically involves managing and maintaining essential documents related to clinical trials. Professionals in this role ensure that all trial documentation complies with regulatory requirements and is audit-ready. They may work with electronic TMF (eTMF) systems, collaborate with study teams, and ensure document accuracy and completeness. TMF specialists play a crucial role in supporting clinical research compliance and regulatory submissions.

What are the main responsibilities of a TMF Specialist on a daily basis?

As a TMF Specialist, your daily responsibilities include maintaining and updating essential clinical trial documents, ensuring accurate filing and compliance with regulatory standards, and performing routine quality checks on documentation. You will collaborate closely with clinical operations, project managers, and external stakeholders to gather and validate needed materials. Attention to deadlines and meticulous organization are critical, as audits and inspections may require quick access to correctly archived files. This hands-on role is vital for ensuring that all documentation is complete, accurate, and ready for review throughout the life cycle of a clinical trial.

More about Tmf jobs
What cities are hiring for Tmf jobs? Cities with the most Tmf job openings:
What are the most commonly searched types of Tmf jobs? The most popular types of Tmf jobs are:
What states have the most Tmf jobs? States with the most job openings for Tmf jobs include:
What job categories do people searching Tmf jobs look for? The top searched job categories for Tmf jobs are:
Tmf jobs near you
Infographic showing various Tmf job openings in the United States as of July 2026, with employment types broken down into 100% Full Time. Highlights an 60% In-person, and 40% Remote job distribution, with an average salary of $83,169 per year, or $40 per hour.
Associate Director, TMF Operations

Associate Director, TMF Operations

SystImmune, Inc

Princeton, NJ • On-site

$140K - $180K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 14 days ago

Job description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
We are an emerging biotech company focused on developing transformative oncology therapies. As we advance our clinical pipeline, we are seeking an Associate Director, TMF Operations to lead Trial Master File (TMF) operations across our oncology programs. This role provides strategic leadership and oversight of electronic Trial Master File (TMF) operations, enhancing functionality, efficiency, scalability, and quality. The ideal candidate will possess TMF system and process expertise, exceptional vendor oversight, and a strong foundation in inspection readiness and support.
Beyond TMF responsibilities, this position oversees Clinical Operations reporting, metrics, KPIs, and analytics. The role involves collaborating with senior leaders and key stakeholders to establish, manage, and generate reports and analytics that support performance measurement, delivery optimization, and continuous improvement.
This position currently requires a minimum of three days onsite per week in Princeton, NJ. The company reserves the right to modify onsite requirements, including transitioning to full-time onsite, based on business needs.
Responsibilities
  • Provide leadership and strategic direction to ensure TMF processes and related documentation are of the highest quality for in-house and outsourced studies.
  • Develop and oversee global TMF-related standards, standard operating procedures (SOPs) and TMF Plans that are in line with relevant regulations and industry best practices.
  • Ensure TMF structure aligns with the DIA TMF Reference Model and supports complex oncology protocols (e.g., adaptive designs, biomarker-driven studies).
  • Provide expertise and leadership to ensure TMF inspection readiness and facilitate seamless support of audits and regulatory inspections.
  • Develop, generate, analyse, and report on standard TMF metrics/KPIs to demonstrate TMF health.
  • Facilitate and perform periodic TMF health checks and QC reviews to ensure completeness, accuracy, and timeliness.
  • Provide operational leadership to TMF vendor budget negotiations and management of TMF operations spend.
  • Create and lead training across all relevant business units/functional areas on business processes around clinical document management and eTMF system(s).
  • Oversee CRO/vendor partners to ensure TMF tasks are completed according to contractual requirements.
  • Serve as area representative for the implementation of any systems or processes that would interface/integrate with TMF (e.g., CTMS, EDMS, ISF, CDMS/EDC).
  • Partner with IT and internal clinical business operations resources to support the strategic lifecycle of TMF including, but not limited to, version releases, system updates, validation or user acceptance testing, and integrations with other clinical applications through change management
  • Oversee and support the registration, maintenance, and compliance of clinical trial postings on appropriate clinical trial registries (e.g., ClinicalTrials.gov) in coordination with the cross-functional team.
  • Support the development and coordination of procedures and programs to enhance team understanding and compliance with clinical trial disclosure regulations and requirements.

Qualifications
  • Bachelor's degree or a combination of relevant education and applicable experience may be considered.
  • 10+ years of experience in clinical research within the pharmaceutical/biotech industry and a minimum of 5 years in TMF process management and oversight.
  • Demonstrated proficiency with eTMF systems and TMF metrics/reporting,
  • Experience with Veeva eTMF platform, strongly preferred.
  • Strong understanding of ICH-GCP, DIA TMF Reference Model, and global regulatory requirements.
  • Comfortable working in a fast-paced, evolving environment with limited structure.
  • Clear and timely communication skills.
  • Strong organizational/prioritization skills for the management of workload and attention to detail.

Compensation and Benefits:
The expected base salary range for this position is $140,000 - $180,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's level qualifications, experience, and skills.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

Apply