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Principal Technical Writer Jobs (NOW HIRING)

Principal Technical Lead

Albuquerque, NM · On-site

$165K - $205K/yr

Auria is looking to hire a Principal Technical Lead to support HADES. This opening requires ... Excellent verbal, written, communication, and leadership skills. * Mission-Driven Professional:

This position requires a demonstrated/thorough understanding and application of technical writing, and configuration management principals and processes. The successful candidate must be effective at ...

The Principal Partner Technical Strategist will serve as the central technical leader for the Americas Channel, focusing on building scalable processes and tools to support partner technical needs ...

Senior Technical Writer

Hampton, VA · On-site

$80K - $120K/yr

This position requires a demonstrated/thorough understanding and application of technical writing, and configuration management principals and processes. The successful candidate must be effective at ...

The Technical Writer writes and edits proposals; process documentation; technical reports, user ... Principal Duties and Responsibilities : * Confer with customers, vendors, or publisher to establish ...

The Technical Writer writes and edits proposals; process documentation; technical reports, user ... Principal Duties and Responsibilities : * Confer with customers, vendors, or publisher to establish ...

The Technical Writer writes and edits proposals; process documentation; technical reports, user ... Principal Duties and Responsibilities : * Confer with customers, vendors, or publisher to establish ...

Senior Technical Writer

Hampton, VA · On-site

$80K - $120K/yr

This position requires a demonstrated/thorough understanding and application of technical writing, and configuration management principals and processes. The successful candidate must be effective at ...

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Principal Technical Writer information

See salary details

$11K

$186.5K

How much do principal technical writer jobs pay per year?

As of Jul 2, 2026, the average yearly pay for principal technical writer in the United States is $185,359.00, according to ZipRecruiter salary data. Most workers in this role earn between $185,000.00 and $185,500.00 per year, depending on experience, location, and employer.

What is a Principal Technical Writer job?

A Principal Technical Writer is a senior-level professional responsible for creating, managing, and improving technical documentation. They collaborate with engineers, product managers, and other stakeholders to develop user manuals, API documentation, and knowledge bases. In addition to writing, they often set documentation standards, mentor junior writers, and contribute to content strategy. Their work ensures technical information is clear, concise, and accessible for both internal and external users.

What are the key skills and qualifications needed to thrive in the Principal Technical Writer position, and why are they important?

To thrive as a Principal Technical Writer, you typically need advanced expertise in technical communication, a strong grasp of complex technical concepts, and a bachelor's degree in English, Communications, Computer Science, or a related field. Proficiency with industry-standard authoring tools (such as Adobe FrameMaker, MadCap Flare, and XML-based content management systems) and relevant certifications (like Certified Professional Technical Communicator) is highly beneficial. Leadership ability, collaboration, and excellent project management and communication skills are key soft skills in this role. These competencies are crucial for producing clear, accurate documentation while guiding teams and collaborating across departments to meet organizational goals.

What are the main challenges Principal Technical Writers face, and how are they typically addressed within organizations?

Principal Technical Writers often face the challenge of communicating highly complex technical information to diverse audiences, including both technical and non-technical stakeholders. To address this, they collaborate closely with engineers, subject matter experts, and product managers to ensure accuracy and clarity in documentation. Organizations usually support Principal Technical Writers with access to advanced tools, ongoing training, and opportunities to participate in product development cycles early on. Effective teamwork, regular knowledge sharing, and established review processes also help in overcoming these unique challenges and ensuring documentation meets high standards. If you enjoy solving complex communication problems in a dynamic, team-oriented environment, this role offers both significant impact and professional satisfaction.

What does a principal technical writer do?

A principal technical writer leads the development of complex technical documentation, such as user manuals, technical guides, and API documentation. They often oversee a team of writers, collaborate with engineers and product managers, and ensure clarity, accuracy, and consistency across materials, typically using tools like Markdown or XML. Strong writing, technical knowledge, and leadership skills are essential for this role.

What is the highest salary for a technical writer?

The highest salaries for principal technical writers can exceed $130,000 annually, especially for those with extensive experience, specialized skills, or working in high-demand industries. Senior technical writers with expertise in tools like XML, DITA, or API documentation may also command higher compensation, often supplemented by bonuses or benefits.

What are the 3 C's of technical writing?

The 3 C's of technical writing are clarity, conciseness, and completeness. These principles help technical writers, including Principal Technical Writers, produce clear and effective documentation that communicates complex information accurately and efficiently.

Are technical writers still in demand?

Technical writers, including principal technical writers, are in steady demand across industries such as technology, healthcare, and engineering. They are valued for their ability to create clear documentation, often requiring skills in tools like Markdown or XML, and certifications can enhance job prospects.
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Infographic showing various Principal Technical Writer job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $185,359 per year, or $89.1 per hour.
Principal Regulatory Writer (Temporary)

Principal Regulatory Writer (Temporary)

Vir Biotechnology

Remote

$180 - $200/hr

Temporary

Posted 7 days ago


Job description

Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.
Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.
We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.
THE OPPORTUNITY
Vir Biotechnology is looking for a Principal Regulatory Writer (Temporary) who will support all aspects of regulatory submissions writing needs. You will collaborate with senior management and other leads to support consistent documents/messaging within and across programs.
This Person will report to the Senior Director, Regulatory Writing.
WHAT YOU'LL DO
  • Craft clear, accurate, and compliant documents required for regulatory submissions to global health authorities including FDA and EMA
  • Write and edit a wide range of regulatory documents, including but not limited to: Clinical trial protocols and amendments, Investigator Brochures (IBs), Clinical Study Reports (CSRs), briefing packages, internal/external facing labeling documents (eg, CCDS/CCSI, annotated draft labels, IFU, patient leaflets, etc), and components of regulatory submission dossiers (eg, NDA, IND, MAA) such as Module 2 and 5 summary documents (eg, SCS, SCE, ISS, etc)
  • Ensure that all written materials strictly adhere to regulatory guidelines, industry standards, and internal quality standards
  • Analyze complex scientific and medical information, including clinical trial data, translating it into clear, concise, and accurate language understandable by both technical and non-technical audiences
  • Work closely with cross-functional teams (eg, clinical research and operations, biostatistics, regulatory affairs, pharmacology, safety, etc) to ensure comprehensive and accurate document content
  • Manage medical writing projects, including developing timelines (working with the study/project teams, as necessary) and communication with cross-functional team members to maintain awareness of review cycles and expectations
  • Participate in cross-functional meetings to provide input regarding medical writing deliverables, timelines, and any process(es) needed for the completion of regulatory documents
  • Participate in defining and writing standard operating procedures and best practices for efficient preparation of quality documents
  • Provide teams with guidance about best practices and industry standards, offer solutions to authoring hurdles, support interaction and understanding across functional areas

WHO YOU ARE AND WHAT YOU BRING
  • Bachelor's and 15 to 20 years of relevant experience required. Advanced degree in science or medical field is a plus
  • Experience with all common study-level and submission-level regulatory documents such as CSRs, IBs, DSURs, protocols, and eCTD modules required
  • Proven experience with marketing applications (INDs, BLAs, NDAs, MAAs, or equivalents) including responses to health authorities, 90/120-day safety updates, or other post-submission activities required
  • Expert understanding of eCTD structure and the clinical development process, and in-depth knowledge of document-related ICH guidelines and GxPs
  • Proven ability to manage complex projects and influence cross-functional teams

#LI-AS1
#LI-Remote
WHO WE ARE AND WHAT WE OFFER
The expected hourly range for this position is $180.00 to $200.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.
Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.
All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics.
This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment.
Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.
For hires based in the United States, Vir Biotechnology, participates in E-Verify.
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