Overnight Remote Nurse Practitioner Jobs (NOW HIRING)

Cadence is the clinical AI company automating the treatment of chronic disease. Its Clinical Intelligence takes on the routine, high-volume work of chronic care – monitoring patients, surfacing risks, and coordinating action – so clinicians can focus on the decisions that require them. Grounded in partnerships with more than 20 leading health systems, deep EMR integrations, dedicated medical group, and experience serving a population of more than 100,000 patients, the system learns from real-world care delivery, improving as it scales. Cadence has been recognized by TIME as one of the Top 100 HealthTech Companies and by LinkedIn as a Top Startup (#4, 2025).

The Role

We're hiring a Nurse Practitioner to serve as the primary clinical point of contact for patients navigating their remote care journey.

In this role, you will lead clinical decision-making with a strong emphasis on guideline-directed medical therapy for heart failure, as well as adherence to evidence-based guidelines for type 2 diabetes and hypertension, including proactive and asynchronous medication titration based on patient vitals, symptoms, and trends. You will oversee patients, manage clinical escalations, and collaborate closely with the patient's physician or provider to optimize treatment plans, adjust medications, and determine the appropriate level of care. This role requires a high level of clinical autonomy, strong judgment, and close collaboration with Registered Nurses and Patient Success teams to deliver timely, patient-centered, and scalable remote care.

Although this position is fully remote, it is a highly collaborative, fast-paced clinical role with clear expectations for productivity, responsiveness, and quality.

Licensure Requirements

Required: Active Compact Multi-State RN license

Required: Active NP licensure in TX

Licenses must be active and in good standing at time of hire.

Schedule Requirements

This role is primarily Monday through Friday, with flexible scheduling available around core business hours of 9:00 AM to 6:00 PM.

What You'll Do

• Manage a panel of patients receiving remote care, making timely clinical decisions based on evidence-based guidelines for heart failure, hypertension, and type 2 diabetes.
• Deliver high-quality, evidence-based care by following established clinical protocols and workflows while applying sound clinical judgment to individual patient needs.
• Initiate and titrate guideline-directed medical therapy (GDMT) while collaborating closely with physicians, RNs, and care teams to optimize outcomes.
• Respond promptly to clinical escalations generated through remote patient monitoring, including abnormal vitals, symptoms, and laboratory results.
• Provide both synchronous and asynchronous patient care, including reviewing patient-generated health data, responding to remote patient monitoring alerts, communicating through secure messaging, and conducting scheduled virtual visits when appropriate.
• Deliver safe, efficient, high-quality care while consistently meeting established productivity and documentation expectations.
• Adapt quickly to evolving workflows, software enhancements, and operational processes as we continuously improve our care model.
• Use multiple technology platforms confidently and provide feedback that helps improve our clinical operations and technology.
• Collaborate across clinical and operational teams to identify opportunities to improve patient care, efficiency, and scalability.
• Help shape the future of a rapidly growing digital health organization where every team member contributes to building better processes—not simply following established ones.

These responsibilities are intended to describe the general nature and level of work being performed by personnel assigned to this job classification. They are not to be construed as an exhaustive list of job duties performed by personnel in this classification. Other job related duties may be assigned by management.

Who You Are

Successful Nurse Practitioners at Cadence:

• Balance exceptional patient care with strong operational efficiency.
• Are comfortable working in an environment where workflows evolve rapidly as we grow.
• Embrace change and view new technology and processes as opportunities rather than obstacles.
• Consistently meet productivity expectations while maintaining high-quality clinical decision making.
• Communicate proactively when they encounter barriers or identify opportunities for improvement.
• Take ownership of problems and work collaboratively to solve them.

What You Need

• Active Compact Multi-State RN license.
• Active NP licensure in TX
• 5+ years experience treating patients with chronic diseases (CHF, Hypertension, T2D) either in an outpatient or inpatient setting at a high-performing medical center.
• 3+ years of cardiology experience with a focus on heart failure management and guideline-directed medical therapy (GDMT).
• Active ANCC or AANP certification.
• Master's Degree as a Nurse Practitioner with the willingness to expand state licensure as Cadence adds new markets and partners.
• Home office setup with consistently stable Wi-Fi with strong upload and download speeds. A Wi-Fi speed test is required during the interview process to verify that these standards are met.
• Demonstrated success working in fast-paced environments where priorities, workflows, and technology evolve frequently.
• Comfortable receiving frequent feedback and continuously adapting processes.
• Highly organized with excellent time management and the ability to balance patient care with productivity expectations.
• Self-directed and accountable while working remotely with minimal supervision.
• Curious, resilient, and energized by helping build new ways of delivering care.
• Experience working in a CHF bridge clinic or T2D clinic, a startup environment, and working with remote patient monitoring technology is preferred.
• Comfortable using AI-assisted clinical tools (such as Gemini, Open Evidence, or comparable platforms) while maintaining clinical judgment as the primary guide for every patient decision.

Compensation

The anticipated salary range for this role is $125,000-$150,000 annually, which is based on role scope, level, and location. In addition to base compensation, this role may be eligible for incentive compensation as part of the overall total rewards package. This position is remote and based in the United States. Actual compensation will be determined based on factors including experience, skills, internal equity, and applicable law.

Benefits & Perks

• Competitive pay & equity*
• Fully remote
• Comprehensive health coverage: Medical, dental & vision
• Paid time off
• 401k plan + matching
• Paid parental leave
• Home office stipend

*benefit offerings may vary depending on job profile, job level and worker type