Lab Manager Jobs in Spring, TX (NOW HIRING)

The Research Lab Manager at UT MD Anderson provides advanced technical and managerial support for laboratory-based research programs within Integrative Medicine Research. The Research Lab Manager works closely with the Principal Investigator to oversee daily laboratory operations, support complex preclinical and translational research projects, and ensure regulatory and institutional compliance while maintaining a high-functioning research environment.
The Research Lab Manager plays a central role in coordinating experimental design, laboratory personnel oversight, regulatory documentation, and data management in support of scientific discovery at UT MD Anderson. MD Anderson is a leading institution focused on cancer care, research, education, and prevention. The Research Lab Manager functions with a high degree of independence and accountability while supporting collaborative research efforts across investigators, trainees, and institutional partners.
The ideal candidate for the Research Lab Manager role brings strong laboratory management experience, advanced technical expertise in molecular biology and preclinical research, and the ability to independently design, execute, and troubleshoot experiments while supervising and training laboratory personnel. Experience with regulatory compliance, animal research, analytical instrumentation, and collaborative research environments is essential.
Why Us?
The Research Lab Manager role offers the opportunity to directly support innovative cancer research while contributing to UT MD Anderson's mission of advancing science and improving patient outcomes. This position provides professional growth through leadership, technical depth, and collaboration within a world-class research environment that supports work-life balance and long-term career development.
• Employer-paid medical coverage starting day one for employees working 30+ hours/week, plus optional group dental, vision, life, AD&D, and disability insurance.
• Accruals for PTO and Extended Illness Bank, plus paid holidays, wellness, childcare, and other leave options.
• Tuition Assistance Program after six months of service and access to extensive wellness, fitness, and employee resource groups.
• Defined-benefit pension through the Teachers Retirement System, voluntary retirement plans, and employer-paid life and reduced salary protection programs.
The ideal candidate will have experience in processing and analyzing multi-omics datasets, with a strong emphasis on single cell sequencing and spatial transcriptomics.
Responsibilities
Laboratory Operations & Research Execution
• Assist the Principal Investigator with scientific research projects involving molecular, biochemical, biophysical, and physiological approaches
• Perform bench-based experiments including mammalian cancer and tumor cell culture and functional assays
• Conduct assays related to cell proliferation, cell death, invasion, migration, voltage potential, and mechanism-based studies
• Independently design and initiate research experiments and validate targets, optimize compound selection, and explore therapeutic potential
• Plan experiments based on results and troubleshoot experimental challenges using critical thinking and prior knowledge
Molecular Biology & Analytical Techniques
• Perform DNA, RNA, and protein extraction, quantification, and analysis
• Conduct agarose and polyacrylamide gel electrophoresis and hybridization techniques including Southern, Northern, Western blots, and in situ hybridization
• Perform real-time quantitative RT-PCR, PCR, primer design, recombinant DNA cloning, subcloning, restriction mapping, BAC clone use, and DNA sequence analysis
• Analyze small molecules or metabolites using LC/MS-MS instrumentation
Animal Research & Preclinical Support
• Conduct animal maintenance, inventory management, breeding, anesthesia, euthanasia, genotyping, and treatment administration
• Perform intravenous, intraperitoneal, gavage, and other treatment delivery methods
• Assist with animal imaging procedures and tissue harvesting
Laboratory Management, Compliance & Oversight
• Support managerial duties including planning training and research activities for assigned laboratory personnel
• Supervise job performance and ensure personnel have required supplies and resources
• Maintain laboratory compliance with institutional and regulatory guidelines
• Prepare, edit, and submit IBC protocols and maintain laboratory safety documentation and chemical inventories
• Submit and track laboratory orders using FileMaker and iLAB and maintain updated CFS and vendor records
• Monitor workflow, plan supply needs, maintain equipment, and prepare stock solutions
Data Management, Clinical Support & Collaboration
• Assist with sample collection, biomarker analysis, and data analysis from human clinical trials
• Collect, store, and perform preliminary analysis of research and clinical data in accordance with approved protocols
• Compile, write, and submit project results to Principal Investigators and collaborating investigators
• Organize laboratory activities and obtain permissions for visitors, contracts, and interns
• Supervise and train new laboratory personnel and interns
• Collaborate with technicians, students, postdoctoral fellows, visiting scientists, and staff using established scientific protocols
Other duties as assigned.
EDUCATION:
Required: Bachelor's Degree
Preferred: Master's Degree One of the natural sciences or related field.
EXPERIENCE:
Required: Seven years scientific, research or clinical laboratory, to include four years in a supervisory/managerial capacity. With Master's degree, five years in a supervisory/managerial capacity, with Master's degree. Successful completion of the LEADing Self Accelerate program may substitute for one year of required supervisory or management experience. LEADing Self Accelerate program may substitute for one year of required supervisory or management experience.
Preferred: Experience in processing and analyzing multi omic datasets, with a strong emphasis on single cell sequencing and spatial transcriptomics.
OTHER REQUIREMENTS: Must pass pre-employment skills test as required and administered by Human Resources.
The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.
This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state, or local laws unless such distinction is required by law.http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html