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Downstream Process Jobs (NOW HIRING)

Lundbeck

Downstream Development Associate II

Bothell, WA · On-site

$38 - $45/hr

Summary: Performs downstream process development experiments and supporting activities, which enable both early and late-stage manufacturing process design for therapeutic monoclonal antibody ...

Lonza

Scientist II, Downstream

Houston, TX · On-site

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

Lonza

Scientist II, Downstream

Houston, TX

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

Lundbeck

Downstream Development Associate II

Bothell, WA · On-site

$38 - $45/hr

Summary: Performs downstream process development experiments and supporting activities, which enable both early and late-stage manufacturing process design for therapeutic monoclonal antibody ...

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How much do downstream process jobs pay per hour?

As of Jun 26, 2026, the average hourly pay for downstream process in the United States is $24.67, according to ZipRecruiter salary data. Most workers in this role earn between $19.71 and $28.12 per hour, depending on experience, location, and employer.

What are some common challenges faced by professionals working in downstream process roles within biomanufacturing?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What are the key skills and qualifications needed to thrive as a Downstream Process Engineer, and why are they important?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What is a Downstream Process in biotechnology?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.
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Downstream Process jobs near you
Analytical Scientist (Downstream Process)

Analytical Scientist (Downstream Process)

Eurofins Scientific

West Point, PA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 4 days ago

Eurofins rating

7.5

Company rating: 7.5 out of 10

Based on 177 frontline employees who took The Breakroom Quiz

57th of 103 rated laboratories

Job description

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description
  • Perform lab-scale downstream processing of vaccine products and process intermediates
  • Perform assays on vaccine products, process intermediates, and related experimental samples using biochemical/analytical tests
  • Prepare solutions/reagents
  • Set-up process equipment for lab-scale experiments
  • Maintain records and experimental results following good manufacturing practices (GMP)

Role will be working with BSL2 biological agents, such as live viruses

Qualifications

Minimum Requirements:

  • Completed bachelors degree in a scientific concentration

  • Pharmaceutical/biotech industry experience with SDS-PAGE, Western blot, Simple Western, HPLC / UPLC, SEC, cIEF, flow cytometry, DLS / SLS (light scattering methods), plate reader fluorescence / luminescence, A260/280, and/or SoloVPE

  • Strong organizational skills and data management (e.g., electronic laboratory notebook compliance, Empower or similar chromatogram integration software)
  • Aseptic sample handling skills and experience (working in a Biosafety Cabinet)
  • Willing and able to work safely with BSL2 biological agents, such as live viruses
  • Ability to work in a dynamic team-centered environment, coordinating work with team leads and colleagues with strong communication skills

Preferred Qualifications:

  • Hands-on experience with small scale bioprocess unit operations (e.g., depth filtration, preparatory chromatography / FPLC, tangential flow filtration, bioburden reduction / sterile filtration)
Additional Information

Position is full-time, Monday-Friday, generally 8 a.m. - 5 p.m., but may vary to meet the assay needs; overtime as needed. Candidates currently living within a commutable distance of West Point, PA are encouraged to apply.

  • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

What Eurofins employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About Eurofins

Sourced by ZipRecruiter

Industry

Scientific research and development services, biotechnology research and development and environmental consulting services

Company size

10,000+ Employees

Headquarters location

Leacock, PA, US

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