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Director Of Laboratory Operations Jobs (NOW HIRING)

Oncohost

Director of Laboratory Operations

Cary, NC · On-site

$150 - $190/hr

Role Overview The Director of Laboratory Operations will lead the company's CLIA‑certified laboratory operations in Cary, North Carolina. This role is responsible for ensuring high‑quality ...

Zunch Staffing

Director of Laboratory

Christiansburg, VA

$90K - $150K/yr

Director of Laboratory Location: Roanoke, VA Salary Range: $90,000 to $150,000 per year Job Summary ... Detailed knowledge of laboratory operations, hospital financial operations, and laboratory and ...

KA Recruiting Inc.

Director of Laboratory Services

Marfa, TX · On-site

$110K - $143K/yr

Director of Laboratory Services Full-Time | Monday-Friday | Relocation Assistance Available Are you ... Direct, develop, and oversee all laboratory operations, policies, and procedures. * Collaborate ...

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$45K

$126.1K

$186K

How much do director of laboratory operations jobs pay per year?

As of Aug 12, 2026, the average yearly pay for director of laboratory operations in the United States is $126,086.00, according to ZipRecruiter salary data. Most workers in this role earn between $106,000.00 and $138,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a director of laboratory operations?

To thrive as a Director of Laboratory Operations, you need extensive laboratory experience, a relevant advanced degree (such as in biology, chemistry, or medical technology), and proven leadership capabilities. Familiarity with laboratory information management systems (LIMS), regulatory compliance tools (CLIA, CAP, ISO 15189), and project management software is typically required. Strong organizational, communication, and problem-solving skills enable effective team leadership and cross-departmental collaboration. These competencies ensure operational efficiency, regulatory compliance, and high-quality scientific output in a complex laboratory environment.

What is the difference between Director Of Laboratory Operations vs Laboratory Manager?

AspectDirector Of Laboratory OperationsLaboratory Manager
CredentialsOften requires advanced degrees (e.g., Master's or PhD) and leadership experienceTypically requires a bachelor's or master's degree in a related field
Work EnvironmentOversees multiple labs or departments, strategic planningManages daily lab activities, staff supervision
Industry UsageUsed in large healthcare, research, or industrial labsCommon in hospital, clinical, or research labs
Search & ComparisonOften searched by those seeking leadership roles in labsMore focused on operational management

The Director Of Laboratory Operations typically holds a higher-level leadership role, overseeing multiple labs and strategic initiatives, while a Laboratory Manager focuses on daily operations and staff management within a specific lab. Both roles require relevant credentials, but the director position usually demands more extensive experience and advanced education.

What are some typical challenges faced by a director of laboratory operations, and how can they be addressed?

Directors of Laboratory Operations often encounter challenges such as managing cross-functional teams, ensuring regulatory compliance, and optimizing workflow efficiency. Balancing the demands of research, quality assurance, and budget constraints requires strong leadership and effective communication. Proactively implementing standardized procedures, fostering a culture of continuous improvement, and staying up-to-date with industry regulations can help address these challenges and ensure smooth laboratory operations.

What does a director of laboratory operations do?

A Director of Laboratory Operations oversees the daily functions and strategic direction of a laboratory. This role is responsible for ensuring that the lab meets regulatory standards, manages staff, and maintains quality control processes. They also handle budgeting, resource allocation, and liaise with other departments or external partners. The director plays a key role in implementing new technologies, optimizing workflows, and ensuring the lab operates efficiently and safely.
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Director Of Laboratory Operations jobs near you
Infographic showing various Director Of Laboratory Operations job openings in the United States as of August 2026, with employment types broken down into 86% Full Time, 11% Part Time, 1% Temporary, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $126,086 per year, or $60.6 per hour.

Director of Laboratory Operations

Oncohost

Cary, NC • On-site

$150 - $190/hr

Other

Posted 7 days ago

Job description

OncoHost is a technology-driven leader in precision medicine, advancing patient outcomes through innovative, clinically validated diagnostic solutions. The company’s proprietary PROphet® platform enables physicians to predict treatment efficacy, supporting more informed, data-driven immuno-oncology decisions.

Role Overview

The Director of Laboratory Operations will lead the company’s CLIA‑certified laboratory operations in Cary, North Carolina. This role is responsible for ensuring high‑quality, compliant, and efficient laboratory operations while aligning operational execution with the company’s scientific and clinical goals.

Duties and Responsibilities Leadership & Team Management
  • Directly manage and mentor the Laboratory General Supervisor, laboratory technologists andOffice Admin.
  • Build, train, and develop a high‑performing laboratory team.
  • Set clear goals, priorities, and performance expectations.
  • Ensure effective communication and collaboration across laboratory, R&D, and cross‑functional teams.
Laboratory Operations
  • Oversee daily laboratory operations, including specimen processing, test performance, data analysis, and reporting.
  • Ensure all laboratory activities are performed in accordance with approved procedures and regulatory requirements.
  • Monitor workload, resource allocation, and turnaround times to ensure operational efficiency and scalability.
  • Ensure proper documentation and maintenance of all laboratory records.
  • Provide hands‑on support for benchwork as needed to maintain workflow continuity and turnaround times.
  • Assist with sample accessioning and chain‑of‑custody documentation during peak volume periods or staffing gaps.
  • Periodically perform hands‑on testing runs of the laboratory’s validated assay workflow to maintain technical familiarity, support troubleshooting, and ensure operational coverage.
Quality & Compliance (CLIA / CAP)
  • Ensure full compliance with CLIA regulations (42 CFR Part 493) and laboratory best practices, in close collaboration with the Laboratory Director.
  • Oversee the implementation and ongoing adherence to quality control and quality assurance programs.
  • Ensure accurate and complete documentation of:
  • Quality control activities
  • Instrument calibration and maintenance
  • Equipment verification and validation
  • Ensure proficiency testing is conducted, reviewed, and documented in accordance with regulatory requirements.
  • Lead laboratory audits, inspections, and inspection‑readiness activities.
Problem Solving & Continuous Improvement
  • Identify operational, technical, or quality‑related issues that may impact test performance.
  • Ensure proper investigation, documentation, and resolution of issues, including execution of CAPA processes.
  • Drive continuous improvement initiatives across laboratory workflows.
  • Work closely with leadership, R&D, Quality, Operations, Clinical, and Commercial teams.
  • Support strategic initiatives, including expected product & indication launches and laboratory scaling activities.
  • Contribute to scientific and operational planning.
Qualifications
  • Master’s or PhD in Life Sciences (Biology, Biochemistry, Molecular Biology, Immunology, or related field).
  • Minimum of 5 years of experience in a clinical laboratory performing high‑complexity testing.
  • Prior experience in a leadership or supervisory role (e.g., General Supervisor or equivalent).
  • Strong knowledge of CLIA regulations and laboratory quality systems.
  • Experience with automated high‑complexity assays.
  • Familiarity with proteomics assays and microarray technologies (e.g., Agilent) is a plus.
  • Strong leadership, organizational, and interpersonal skills.
  • Detail‑oriented with strong problem‑solving capabilities.
  • Ability to work independently with remote supervision.
  • Highly motivated with a proactive, results‑driven mindset.
Working Conditions
  • This is an on‑site position requiring presence in the office five days per week, with flexibility as needed to support laboratory operations.
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