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Associate Director Of Clinical Operations Jobs (NOW HIRING)

ARTBIO

Senior Director, Clinical Operations

Cambridge, MA · On-site

$120 - $160/hr

Summary The Senior Director of Clinical Operations oversees all aspects of clinical trial execution, including start-up, monitoring, and close-out activities for all ARTBIO programs. This key role ...

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How much do associate director of clinical operations jobs pay per year?

As of Aug 14, 2026, the average yearly pay for associate director of clinical operations in the United States is $145,969.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,000.00 and $173,500.00 per year, depending on experience, location, and employer.

What are some common challenges faced by an associate director of clinical operations, and how can they be effectively managed?

Associate Directors of Clinical Operations often encounter challenges such as coordinating cross-functional teams, ensuring regulatory compliance, and managing tight project timelines. Balancing the needs of different stakeholders—including clinical staff, regulatory bodies, and sponsors—requires strong communication and organizational skills. Proactively addressing potential bottlenecks, maintaining open lines of communication, and fostering collaborative relationships across departments are key strategies for overcoming these challenges. Additionally, staying updated on industry regulations and best practices helps ensure smooth clinical trial execution and successful project outcomes.

What does an associate director of clinical operations do?

An Associate Director of Clinical Operations oversees the planning, execution, and management of clinical trials within a healthcare or pharmaceutical organization. They ensure that studies comply with regulatory requirements, company standards, and timelines. Their responsibilities often include managing clinical teams, collaborating with cross-functional departments, and overseeing budgets and resources. This role is pivotal in driving clinical programs from start to finish, ensuring quality and efficiency in all operations.

What is the difference between Associate Director Of Clinical Operations vs Clinical Project Manager?

AspectAssociate Director Of Clinical OperationsClinical Project Manager
ResponsibilitiesOversees multiple clinical projects, manages teams, and develops operational strategiesManages individual clinical trials, coordinates project activities, and ensures timelines
Required CredentialsBachelor's or higher in life sciences, with experience in clinical operationsBachelor's in life sciences or related field, with project management experience
Work EnvironmentCorporate clinical operations departments, often in biotech or pharma companiesClinical trial sites, CROs, or pharmaceutical companies

The Associate Director Of Clinical Operations typically oversees multiple projects and manages teams, focusing on strategic operational functions. In contrast, a Clinical Project Manager handles specific clinical trials, focusing on day-to-day project execution. Both roles require relevant scientific credentials and experience in clinical settings, but their scope and responsibilities differ significantly.

What are the key skills and qualifications needed to thrive as an associate director of clinical operations?

To excel as an Associate Director of Clinical Operations, you need a solid background in clinical research, regulatory compliance, and project management, typically supported by an advanced degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) guidelines, and industry certifications such as PMP or CCRP is highly beneficial. Outstanding leadership, strategic thinking, and effective communication skills set top performers apart in this role. These competencies ensure efficient study execution, regulatory adherence, and team coordination, which are critical for successful clinical trial outcomes.
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Associate Director Of Clinical Operations jobs near you
Infographic showing various Associate Director Of Clinical Operations job openings in the United States as of August 2026, with employment types broken down into 86% Full Time, 11% Part Time, 1% Temporary, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $145,969 per year, or $70.2 per hour.

Associate Director, Clinical Operations (Late-Phase)

Latigo Biotherapeutics

San Francisco, CA • On-site

$180K - $195K/yr

Full-time

Re-posted 11 days ago

Job description

Job: Associate Director, Clinical Operations (Late-Phase)
Location: Thousand Oaks, CA or San Francisco, CA
Position type: Full Time
Reports to: Senior Director, Clinical Operations
Position Summary:
Reporting to the Senior Director, Clinical Operations, the Associate Director will be responsible for leading the execution of assigned late-phase clinical trials. This individual will work directly with the cross-functional study team to define and implement the operational strategy for assigned trials, and deliver on milestones within prescribed timelines and budget, and with high quality. The ideal candidate will be experienced in leading Phase 2 and Phase 3 multi-center trials, possess strong verbal and written communication skills, and be able to work effectively and independently in a fast-paced environment.
Candidates should be local to Thousand Oaks, CA or the San Francisco Bay area.
Responsibilities include (but are not limited to):
  • Define and implement the operational strategy for assigned clinical trials, in collaboration with the cross-functional team and clinical leadership.
  • Provide expertise into the development of clinical documents (eg., study protocols and amendments, investigator brochures, case report forms, informed consent forms, study plans, site manuals, etc.). Author portions of clinical documents as required.
  • Develop and manage trial timelines to ensure alignment with overall program objectives and milestones.
  • Effectively manage trial communication to ensure stakeholders are informed of and aligned on trial activities and progress.
  • Proactively identify, communicate, and manage risks that may affect trial milestones, quality, or budget.
  • Identify and select qualified vendors. Responsible for vendor performance management.
  • Perform co-monitoring, as required, to support site, vendor and trial oversight.
  • Ensure clinical studies are conducted in compliance with SOPs, ICH/GCP guidelines, and FDA regulations. Oversee and ensure high quality of clinical trial execution and trial data.
  • Oversee and direct clinical contractors, as required.
  • Oversee and ensure accuracy of clinical trial budgets. Oversee accruals reporting and forecasting for assigned trials. Review vendor invoices for accuracy.
  • Contribute to Clinical Operations resource and budget planning.
  • Contribute to the development of department SOPs, systems, policies, best practices, and standards that support high quality clinical trial execution and GCP inspection readiness.
  • May manage direct reports, including ongoing performance management, mentorship, and career development.
  • Up to 25% travel may be required, consistent with project needs.

Minimum Requirements:
  • Bachelor's Degree in life sciences
  • 8 years relevant industry experience
  • >3 years of experience on acute and/or chronic pain studies.
  • Proficient knowledge of ICH GCP, CFR, and other applicable regulatory requirements for clinical trial conduct.
  • Prior experience directing and managing Phase 2 and Phase 3 clinical trials. Prior experience with pain or analgesia trials preferred but not required.
  • Prior experience with resource, budget, and vendor management.
  • Demonstrated critical thinking, problem solving, and negotiation skills
  • Demonstrated ability to successfully work in cross-functional project teams with an emphasis on teamwork, collaboration, and communication.
  • Excellent interpersonal and communication skills with ability to relate to both internal and external stakeholders (e.g., scientific advisors, clinical consultants, CROs, investigators).
  • Self-disciplined, detail-oriented, and able to prioritize tasks to meet critical deadlines.

Apply