Director/Sr Director, Translational Biomarkers
- $185,000 to $245,000 Yearly
- Full-Time
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI and San Diego, CA. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
We are looking for a highly motivated and experienced Director/Sr. Director to join our Translational Biomarkers team. The successful candidate will oversee a team of people and be accountable for strategic leadership and oversight of assay development and execution in support of early stage clinical research studies. The Translational Biomarkers Director will work closely with discovery and clinical teams to align efforts with program needs and ensure high quality standards and timely reporting.
Responsibilities
- Direct and oversee Translational Biomarkers activities to ensure achievement of department objectives; proactively collaborate with discovery and clinical teams to align efforts with program needs
- Develop and execute the strategy for operating objectives, organizational structure, staffing requirements, space and instrumentation
- Oversees in-house infrastructure, systems and procedures to ensure fit for purpose laboratory practices for analytical methods and testing in clinical study samples
- Implement and maintain efficient processes and procedures to provide high quality standards and study design, study execution and timely reporting
- Maintain up-to-date knowledge of current industry practices
- Monitor performance of direct reports and ensure that management training and development needs are addressed
Requirements:
- Ph.D and 10+ years of experience OR Master's and 18+ years of experience
- 10 years relevant laboratory experience in a contract research organization, biotechnology or pharmaceutical environment, working to Good Laboratory Practice (GLP) standards, including management experience and budget responsibility
- Demonstrated ability in problem solving, quantitative and critical thinking
- Ability to handle multiple projects, meet deadlines and make decisions
- Proficient project management, presentation and communication skills
- Familiarity with diverse bioanalytical methods, including qRT-PCR, ELISA, MSD, Quanterix, SMC, LC-MS/MS
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.
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