Principal Clinical Database Programmer

Principal Clinical Database Programmer Salary

$116K

$166K

$243K

$175,884

/year

$84.56

/hour

Principal Clinical Database Programmer Salary Comparison by Location

Nationwide

United States

$175,884

Columbus

Ohio

$169,886

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    How much does a Principal Clinical Database Programmer make?

    As of Aug 14, 2026, the average annual pay for a Principal Clinical Database Programmer in the United States is $175,884 a year.

    Just in case you need a simple salary calculator, that works out to be approximately $84.56 an hour. This is the equivalent of $3,382/week or $14,657/month.

    While ZipRecruiter is seeing annual salaries as high as $243,000 and as low as $116,000, the majority of Principal Clinical Database Programmer salaries currently range between $151,500 (25th percentile) to $203,000 (75th percentile) with top earners (90th percentile) making $240,000 annually across the United States. The average pay range for a Principal Clinical Database Programmer varies greatly (by as much as 51500), which suggests there may be many opportunities for advancement and increased pay based on skill level, location and years of experience.

    A Principal Clinical Database Programmer in your area makes on average $169,886 per year, or $5,998 (3.410%) less than the national average annual salary of $175,884. Ohio ranks number 30 out of 50 states nationwide for Principal Clinical Database Programmer salaries.

    To estimate the most accurate annual salary range for Principal Clinical Database Programmer jobs, ZipRecruiter continuously scans its database of millions of active jobs published locally throughout America.

    Find your next high paying job as a Principal Clinical Database Programmer on ZipRecruiter today.

    What are Top 10 Highest Paying Cities for Principal Clinical Database Programmer Jobs

    We've identified 10 cities where the typical salary for a Principal Clinical Database Programmer job is above the national average. Topping the list is Nome, AK, , with Redwood City, CA, and Sitka, AK, close behind in the second and third positions. Sitka, AK, beats the national average by $35,999 (20.5%), and Nome, AK, furthers that trend with another $42,299 (24.0%) above the $175,884 average.

    With these 10 cities having average salaries higher than the national average, the opportunities for economic advancement by changing locations as a Principal Clinical Database Programmer appears to be exceedingly fruitful.

    Finally, another factor to consider is the average salary for these top 10 cities varies very little at 5% between Nome, AK, and Alamo, CA, , reinforcing the limited potential for much wage advancement. The possibility of a lower cost of living may be the best factor to use when considering location and salary for a Principal Clinical Database Programmer role.

    City

    Annual Salary

    Hourly Wage

    Nome, AK

    $218,183

    $104.90

    Redwood City, CA

    $215,344

    $103.53

    Sitka, AK

    $211,883

    $101.87

    South San Francisco, CA

    $211,173

    $101.53

    San Francisco, CA

    $207,221

    $99.63

    Palo Alto, CA

    $206,755

    $99.40

    Santa Clara, CA

    $206,564

    $99.31

    Sunnyvale, CA

    $206,426

    $99.24

    Livermore, CA

    $206,309

    $99.19

    Alamo, CA

    $206,178

    $99.12

    What are Top 5 Best Paying Related Principal Clinical Database Programmer Jobs in the U.S.

    Analyzing some similar jobs related to the Principal Clinical Database Programmer job category, we found that Cloud Software Engineer jobs have average salaries similar than Principal Clinical Database Programmer jobs.

    Job Title

    Annual Salary

    Hourly Wage

    Cloud Software Engineer

    $142,296

    $68.41

    Autonomous Systems Engineer

    $127,215

    $61.16

    Cuda Developer

    $111,845

    $53.77

    Application Engineer I

    $110,698

    $53.22

    Software Developer Engineer

    $100,265

    $48.20

    About Our Data

    ZipRecruiter salary estimates, histograms, trends and comparisons are derived from both employer job postings and third party data sources.

    Infographic detailing Principal Clinical Database Programmer salary across the United States as of August 2026. Displays a bar chart with salary percentiles, a national average salary of $175,884 per year or $84.56 an hour, and a color-coded map showing state-by-state salary variations.