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Senior Ai Software Engineer Jobs in Ohio (NOW HIRING)

Senior Agentic AI Software Engineer

Columbus, OH · On-site +1

$160K - $279K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Job Summary The Senior Agentic Software Engineer will develop financial technology solutions within the rapidly evolving AI world. This includes utilizing/extending agentic protocols for impact in ...

Software Engineer Senior- AI engineer

Strongsville, OH · On-site

$86K - $172K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

As a Software Engineer Senior within PNC's Technology organization, you will be based in Houston, TX; Dallas, TX; Pittsburgh, PA; Cleveland, OH or Birmingham, AL. PNC is seeking an AI Engineer with ...

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Senior Ai Software Engineer information

What is the salary of senior AI software engineer in AI?

The salary of a senior AI software engineer typically ranges from $100,000 to $160,000 annually, depending on experience, location, and company size. Additional compensation may include bonuses, stock options, and benefits, especially in competitive tech environments requiring expertise in machine learning, deep learning, and programming languages like Python or TensorFlow.

What does a senior AI software engineer do?

As a Senior AI Software Engineer, you will frequently work cross-functionally with data scientists and product teams to design, develop, and deploy AI solutions. You’ll translate complex models developed by data scientists into scalable, production-ready code, and ensure the solutions meet performance and reliability standards. Regular communication with product managers and stakeholders is essential to align technical deliverables with business objectives, and you may also mentor junior engineers in best practices for AI system integration.

What are the key skills and qualifications needed to thrive as a senior AI software engineer?

To thrive as a Senior AI Software Engineer, you need deep expertise in machine learning, programming languages such as Python or Java, and a strong background in computer science or a related field, often with an advanced degree. Familiarity with frameworks like TensorFlow or PyTorch, experience deploying models to production, and knowledge of cloud platforms are typically required, along with certifications in AI or data science being advantageous. Strong problem-solving abilities, leadership, and effective communication skills distinguish top performers in this role. These skills ensure the ability to design, build, and scale AI solutions that drive innovation and deliver business value.

What is a senior AI software engineer?

Senior AI Software Engineers are experienced professionals who design, develop, and deploy artificial intelligence (AI) systems and applications. They lead complex projects involving machine learning, deep learning, and data analysis, often mentoring junior engineers and collaborating with data scientists. Their responsibilities include creating scalable AI models, optimizing algorithms, and ensuring that AI solutions meet business objectives. They typically possess advanced knowledge of programming languages such as Python and experience with AI frameworks like TensorFlow or PyTorch. Additionally, they stay updated on the latest AI trends and best practices to drive innovation within their organizations.

What is the difference between Senior Ai Software Engineer vs Data Scientist?

AspectSenior Ai Software EngineerData Scientist
Required CredentialsBachelor's/Master's in CS, AI, or related; experience with AI frameworksBachelor's/Master's in CS, Statistics, or related; experience with data analysis
Work EnvironmentDevelops AI models, software, and algorithms; collaborates with engineering teamsAnalyzes data, builds predictive models, interprets data insights
Employer & Industry UsageTech companies, AI startups, R&D departmentsTech firms, finance, healthcare, research institutions

While both roles require strong technical skills and experience with AI tools, Senior Ai Software Engineers focus on developing and deploying AI software solutions, whereas Data Scientists primarily analyze data to generate insights and build predictive models. The roles often overlap but differ in their core responsibilities and focus areas.

What cities in Ohio are hiring for Senior Ai Software Engineer jobs? Cities in Ohio with the most Senior Ai Software Engineer job openings:
Infographic showing various Senior Ai Software Engineer job openings in Ohio as of August 2026, with employment types broken down into 1% Internship, 87% Full Time, 6% Part Time, and 6% Contract. Highlights an 87% Physical, 4% Hybrid, and 9% Remote job distribution.

Senior AI Full stack Software Engineer

McKesson's Corporate

Columbus, OH • On-site

$131 - $218.30/hr

Other

Posted 3 days ago

New


Job description

Senior AI Full Stack Software Engineer – CMM

McKesson is an impact-driven, Fortune 10 company dedicated to improving the quality and accessibility of healthcare. As a Senior AI Full Stack Software Engineer, you will design, develop, and deploy end-to-end AI‑powered solutions that enhance our healthcare and decision‑making platforms.

Key Responsibilities
  • Lead the design and deployment of AI applications that support decision‑making, patient engagement, and operational efficiency.
  • Integrate AI into electronic health records (EHRs) and clinical systems, building scalable solutions that incorporate large language models, voice and image recognition, and document parsing.
  • Develop and optimize secure, HIPAA‑compliant data pipelines for training and deploying AI models using structured and unstructured healthcare data.
  • Apply rigorous evaluation metrics (e.g., sensitivity, specificity, AUC‑ROC) to ensure models meet regulatory and ethical standards.
  • Mentor junior engineers and contribute to the strategic direction of AI initiatives within the organization.
  • Rapidly prototype and iterate AI concepts in collaboration with product representatives.
Minimum Qualifications
  • 10+ years of software engineering experience, with 4+ years in AI/ML development.
  • B.S. degree in Computer Science or related engineering discipline, or equivalent experience.
Critical Skills
  • 2+ years of experience building AI solutions in healthcare or life sciences.
  • Deep understanding of healthcare data standards (HL7, FHIR) and compliance frameworks (HIPAA, GDPR).
  • Proven ability to build AI models for clinical NLP, medical imaging, patient risk stratification, and care personalization.
  • Experience with retrieval‑augmented generation systems using tools such as Pydantic, Semantic Kernel, LangChain, LlamaIndex, and vector databases.
  • Skill in creating custom AI agents or specification‑driven tools and in writing for systems like Claude, Copilot, Codex, etc.
  • Advanced prompt engineering and optimization techniques (prompt tuning, caching, benchmarking).
  • Full‑stack development proficiency in Python, Node.js, and modern web frameworks.
Preferred Skills
  • Experience with secure cloud environments (AWS, GCP, Azure), containerization (Docker, Kubernetes), and CI/CD pipelines.
  • Familiarity with OpenAI, Hugging Face, PyDantic AI, TensorFlow, PyTorch, and healthcare‑specific AI libraries.
  • Strong communication and leadership abilities to convey complex AI concepts to clinical and executive stakeholders and to lead cross‑functional teams.
  • Experience mentoring and developing junior engineers in AI concepts and best practices.
Compensation

Base Pay Range: $131,000 – $218,300.

Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers, including those with disabilities. If you need reasonable accommodation during your job search or application, please contact us at Disability_Accommodation@McKesson.com (U.S.) or Accessibility@mckesson.ca (Canada). Resumes or CVs submitted to this email box will not be accepted.

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