Remote Protein Engineering Jobs (NOW HIRING)

Our Why At Dotmatics
At Dotmatics, we believe science, data, and decision-making must be deeply intertwined for innovation to thrive.
Our Portfolio includes Luma, LumaLab Connect, ELN Platform, Graphpad Prism, Geneious, SnapGene, Protein Metrics, OMIQ, FCS Express, LabArchives, NQuery, EasyPanel, MStar, SoftGenetics and Virscidian.
We have a vision for a new Lab of the Future that will change the future of scientific research.
We have created the world's most comprehensive digital science platform - best-of-breed software applications already used by more than 2 million scientists, together in a single ecosystem united by a powerful, flexible enterprise data platform. This is not flat data buried away in digital graveyards. This is dynamic, multi-dimensional decision-making.
Scientific enterprises need a new level of effectiveness to achieve tomorrow's breakthroughs. Illness will not wait. The biosphere will not wait. We are tireless in our vision, because the time for innovation is now.
Shaping the Future of Science At Dotmatics
Our global team of more than 800 colleagues are dedicated to supporting our customers in over 180 countries. Together, with our scientific community of users, we accelerate scientific innovation in order to make the world a healthier, cleaner, and safer place to live.
You'll join a collaborative, global team pushing the boundaries of scientific innovation. Your ideas and efforts will have a tangible impact, accelerating scientific progress and discovery. We offer a dynamic, remote-friendly environment that fosters high integrity and collaboration, empowering you to excel. Dotmatics is a company built by scientists, for scientists. Combined, we are now the world's largest cloud-based scientific research R&D platform. We need your help to keep growing and pioneering the future.
We are Science Driven. We are Customer Centric. We are Better Together.
What do we Need:
As a Staff Software Engineer, you will be the technical lead for the data processing and execution platform - a set of services that take user-initiated operations (data commits, transformations, workflows) and execute them reliably across shared compute infrastructure. This is a distributed, event-driven system with multiple services coordinating through asynchronous message passing.
This is no ordinary engineering role - this is working on a product with real world meaning - a product that helps define the way scientists works, helping bring medicine to market quicker, finding cures for diseases faster
This is LUMA
**This is a remote position, located in Mass. There will be some travel required to the office in Boston for team meetings and working sessions.**
In this role, you will:

• Define and drive system architecture for event-driven data processing services, leading the migration of key components to a Node.js/TypeScript and Python ecosystem
• Contribute to and improve engineering standards, patterns, and best practices for distributed systems, observability, and reliability across a multi-service platform coordinated through Kafka, GraphQL and RESTful APIs
• Architect and implement asynchronous data processing pipelines for high-volume scientific data, with attention to at-least-once delivery guarantees, backpressure, and graceful degradation
• Guarantee the scalability, maintainability, and security of software solutions running on Kubernetes and AWS
• Take ownership of existing services, develop a deep understanding of their behavior, and make pragmatic decisions about how to evolve them

We are looking for candidates with 12+ years experience in engineering preferably in a SaaS environment, and ideally with a degree in Computer Science, Software Engineering, or equivalent.
The Key Skills we are looking for:

• Language-agnostic engineering mindset - you pick up new languages and codebases quickly, reason about distributed system design independent of any single runtime, and can be productive in an unfamiliar stack within weeks
• Advanced working experience in Asynchronous processing
• Strong proficiency in Node.js/TypeScript and Python for building production backend services
• Proven experience designing and implementing distributed, event-driven systems coordinated through message buses, GraphQL and RESTful APIs
• Experience implementing automated testing platforms, unit tests, and integration tests
• Advanced working experience with large data processing platforms such as Spark, Databricks, or Snowflake
• Experience managing state across multiple stores (e.g. a message bus, a relational database, and a cache) and the consistency challenges that come with it
• Hands-on experience with AWS in production environments and a solid understanding of Kubernetes for orchestrating workloads
• Proficiency with CI/CD tools such as GitHub Actions
• Knowledge of Agile software development practices
• Setting technical direction, leading cross-team initiatives, and leveling up other engineers through mentoring and architectural guidance

You may also have experience in:

• Scala or other JVM languages (helpful for understanding existing services during migration)
• Message-based architectures using Kafka (consumer groups, partitioning, delivery semantics)
• Background in complex data pipelines, schema management, and incremental processing
• Exposure to AWS and/or GCP or designing systems portable across multiple cloud providers
• Building scalable distributed systems using Kubernetes and other cloud-native technologies
• Experience within Life Sciences or R&D data management

Why this role is interesting:
You're not maintaining a system in steady state. You're taking a complex, production-proven execution platform and leading its evolution - migrating to a new tech stack while keeping it running reliably for customers doing drug discovery. The system processes real scientific data through multi-step pipelines on shared compute infrastructure, with all the distributed systems challenges that implies: multi-tenancy, cancellation, crash recovery, and coordinating state across multiple data stores. If you enjoy understanding how complex systems actually work, regardless of what language they happen to be written in, and then making them better - this is the role.
Total Rewards
Dotmatics utilises a national market-based approach to base pay benchmarking and pay band development. The candidate's final starting pay is based on job-related skills, experience, job specific qualifications & location. In addition to base salary, Dotmatics has implemented a total rewards strategy, which is the combination of compensation, benefits and recognition.
Certain positions are also eligible for variable pay; your recruiter will discuss the full compensation package details.
Other Total Rewards Offered

• Medical, Dental, Vision, Insurance
• Health Spending Accounts
• Wellness Benefits (Mental Health Apps and Fitness Perks)
• Company-paid Life and Disability Insurance
• 401k Retirement Plan (with 4% company match; immediate vesting)
• Flexible Time off Plan (for US exempt employees)

This is the range that we, in good faith, believe is the range of possible compensation for this role at the time of this posting. We may ultimately pay more or less than the posted range. This range may be modified in the future.
Base Pay Range
$96,862-$196,574 USD
Research shows us the confidence gap and imposter syndrome can get in the way of meeting outstanding candidates, so please don't hesitate to apply - we'd love to hear from you.
By submitting your application, you agree that Dotmatics may collect your personal data for recruiting, global organization planning, and related purposes. Dotmatics Privacy Notice explains what personal information we may process, where we may process your personal information, our purposes for processing your personal information, and the rights you can exercise over Dotmatics use of your personal information.
Dotmatics is an equal opportunity employer. We are a welcoming place for everyone, and we do our best to make sure all people feel supported and connected at work.