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Remote Clinical Operations Jobs in Colorado (NOW HIRING)

Karoo Health

Director, Clinical Operations

Denver, CO · On-site +1

The Role The Director of Clinical Operations will lead the development, refinement, and execution ... Fully-remote work environment available * Full benefits package * A collaborative and transparent ...

CPC

Clinical & Endpoint Research Associate

Aurora, CO · On-site +1

$60K - $70K/yr

The Clinical & Endpoint Research Associate supports site operations with a primary focus on ... Remote candidates are welcome to apply. In this position you will: * Contact study sites and ...

Nourish

Research Associate

Denver, CO · On-site +1

This person will report into our Head of Research and work closely with our clinical operations, product, data, and commercial teams. This role is full-time and open to NYC-based or remote candidates.

BlueSprig

BCBA - Clinical Director

Aurora, CO · On-site +1

$120K/yr

Option for remote work as operations allow * Paid time off plus holidays * Structure designed to support both leadership and clinical responsibilities What You'll Own * Clinical quality and outcomes ...

ACES

Talent Acquisition Partner

Denver, CO · On-site +1

$26 - $28/hr

Location: 90% remote, 10% in-person for events Schedule: 8-hour shift between 8:00 AM - 6:00 PM Pay ... Partner with Clinical Operations Managers (COMs) and clinical leaders to align on hiring needs and ...

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All JobsClinical Operations JobsRemote Clinical Operations JobsRemote Clinical Operations Jobs in Colorado

Remote Clinical Operations information

See Colorado salary details

$36.8K

$103.1K

$196.1K

How much do remote clinical operations jobs pay per year?

As of Jul 13, 2026, the average yearly pay for remote clinical operations in Colorado is $103,090.00, according to ZipRecruiter salary data. Most workers in this role earn between $76,200.00 and $119,300.00 per year, depending on experience, location, and employer.

What are some typical day-to-day responsibilities for a Remote Clinical Operations professional?

A Remote Clinical Operations professional is responsible for managing and monitoring clinical trial activities from a virtual office, which includes coordinating study timelines, communicating with clinical sites, and ensuring regulatory documentation is up to date. You may also be tasked with overseeing data quality, facilitating team meetings, and ensuring all trial processes adhere to protocols and compliance regulations. Most days involve frequent online collaboration with investigators, sponsors, and cross-functional teams, requiring strong virtual communication skills. The environment is typically dynamic, with priorities shifting based on project milestones and site needs, providing an engaging and varied work experience.

What is a Remote Clinical Operations job?

A Remote Clinical Operations job involves overseeing and managing clinical trials and research activities from a remote location. Professionals in this role ensure studies comply with regulatory requirements, coordinate with cross-functional teams, and monitor trial progress. They work closely with investigators, sponsors, and site staff to ensure efficient trial execution. Strong organizational, communication, and problem-solving skills are essential for success in this position.

What are the key skills and qualifications needed to thrive in the Remote Clinical Operations position, and why are they important?

To thrive as a Remote Clinical Operations professional, you typically need a background in clinical research or healthcare management, along with strong organizational and project management skills. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and industry regulations such as GCP and HIPAA is highly beneficial, and certifications like CCRA or CCRC are often preferred. Exceptional communication, time management, and problem-solving abilities help you collaborate effectively within remote and cross-functional teams. These competencies ensure seamless oversight of clinical trials and adherence to timelines and compliance standards when working remotely.

What are the most commonly searched types of Clinical Operations jobs in Colorado? The most popular types of Clinical Operations jobs in Colorado are:
What are popular job titles related to Remote Clinical Operations jobs in Colorado? For Remote Clinical Operations jobs in Colorado, the most frequently searched job titles are:
What job categories do people searching Remote Clinical Operations jobs in Colorado look for? The top searched job categories for Remote Clinical Operations jobs in Colorado are:
What cities in Colorado are hiring for Remote Clinical Operations jobs? Cities in Colorado with the most Remote Clinical Operations job openings:
Remote Clinical Operations jobs near you
Infographic showing various Remote Clinical Operations job openings in Colorado as of July 2026, with employment types broken down into 82% Full Time, 13% Part Time, and 5% Contract. Highlights an 100% Remote job distribution, with an average salary of $103,090 per year, or $49.6 per hour.
Director, Clinical Operations

Director, Clinical Operations

Karoo Health

Denver, CO • On-site, Remote

Full-time

Posted 12 days ago

Job description

An Industry Defining Company
Karoo is a venture-backed startup on a mission to transform cardiovascular care. Our platform is designed to empower large provider groups and health systems to succeed in value-based care contracts with payers by improving patient outcomes and reducing cost of care through better coordination, analytics, and disease management. We are currently live in multiple VBC contracts across more than ten states with significant growth plans for 2026 and beyond. While our initial focus is cardiology, we are building a scalable operating system for managing complex conditions across the healthcare spectrum.
This is a rare opportunity to join a mission-driven founding team at a pivotal stage and help define the future of healthcare technology, with the power to improve the lives of patients with cardiovascular disease, the number one cause of death in America today.
The Role
The Director of Clinical Operations will lead the development, refinement, and execution of Karoo's clinical care model. This leader will translate clinical strategy into scalable workflows, protocols, staffing models, and operational playbooks to ensure high-quality, compliant, and efficient care delivery across markets.
This role is ideal for a clinically trained operator with cardiology experience who understands value-based care and thrives in early-stage environments where building and iterating are core to the job.
This role will directly shape how care is delivered at Karoo, from the patient experience to clinical outcomes to financial performance under value-based contracts.
What You'll Do
Clinical Model Implementation & Iteration
  • Own the implementation and ongoing refinement of Karoo Health care model, including risk stratification, and condition based care protocol development.
  • Translate evidence-based cardiology guidelines into practical and scalable care protocols.
  • Test, iterate, and standardize care protocols to meet the needs of individual markets and payer arrangements.
  • Ensure the Karoo Health care model supports value-based care (full upside and downside risk) through alignment of patient, provider, and payer specific outcomes.

Clinical Operations Execution
  • Operationalize the clinical model across care teams, developing SOPs, staffing models, role definitions, and training materials.
  • Identify operational bottlenecks or clinical variation and drive continuous improvement initiatives.
  • Support market launches by ensuring clinical readiness, workflows, and staffing are in place.

Care Team Leadership
  • Provide operational support to Karoo's clinical team (RNs, LCSW, MAs, etc.)
  • Support hiring, onboarding, training, and performance management of clinical staff.
  • Foster a culture of patient-centered, data-informed, high-quality care delivery.

Value-Based Care & Performance Management
  • Partner with Analytics and Finance to define and monitor clinical KPIs tied to value-based contracts (e.g., patient engagement, clinical outcomes, utilization, and financial outcomes).
  • Use data to assess clinical effectiveness and identify opportunities to improve outcomes and reduce avoidable utilization.
  • Support shared savings performance by aligning clinical workflows with payer and provider incentives.

Provider Partnership Enablement
  • Collaborate with partner cardiology practices to ensure smooth integration of Karoo's clinical model into existing workflows.
  • Serve as a key operational liaison to practice leaders, addressing day-to-day clinical process questions and improvement opportunities.
  • Support provider onboarding, clinical training, and ongoing adoption of Karoo protocols.

Quality, Safety & Compliance
  • Ensure clinical operations meet regulatory, licensure, and quality standards across states and care settings.
  • Partner with the CMO and clinical leaders on quality oversight, incident review, and continuous quality improvement efforts.
  • Maintain up-to-date clinical policies and documentation standards.

Cross-Functional Collaboration
  • Work closely with Product to inform clinical requirements for tools, workflows, and dashboards.
  • Partner with Market Ops, and Growth teams to align clinical delivery with expansion goals.
  • Provide clinical-operations input into payer discussions and new market planning.

What We're Looking For
  • Clinical background in cardiology. NP, PA, or MD degree is considered a strong plus.
  • 5+ years operational and people management experience.
  • Experience in value-based care provider organizations. Experience with participation in full upside and downside risk arrangements is a plus.
  • Experience building or scaling clinical programs in a startup or established health system.
  • Experience in a value-based provider startup organization is a plus.
  • Strong systems thinker who can translate clinical strategy into operational reality.
  • Comfortable operating in ambiguity and iterating quickly as the organization grows.
  • Collaborative, pragmatic leader with excellent communication skills.

Why Join Us
  • Competitive salary and equity
  • Fully-remote work environment available
  • Full benefits package
  • A collaborative and transparent company culture that values creativity and ownership

Apply