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Clinical Operations Manager Jobs in Colorado (NOW HIRING)

CPC

Clinical Operations Manager II

Aurora, CO · Remote

$71K - $88K/yr

Oversee clinical operations management activities. * Define and monitor project scope, timelines and deliverables from project initiation to close-out. * Identify project-specific training for team ...

CPC

Sr. Clinical Operations Manager

Aurora, CO · On-site +1

Oversee clinical operations management activities when delegated to a Clinical Trial Manager (CTM). For single-site or smaller multi-center studies in which these activities are not delegated to a ...

CPC

Clinical Operations Manager I

Aurora, CO

We are looking for an experienced Clinical Operations Manager I to join our team! Are you well organized, but adaptable to unexpected changes? Someone who is able to see the bigger picture, without ...

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Clinical Operations Manager information

See Colorado salary details

$36.8K

$103.1K

$196.1K

How much do clinical operations manager jobs pay per year?

As of Aug 6, 2026, the average yearly pay for clinical operations manager in Colorado is $103,090.00, according to ZipRecruiter salary data. Most workers in this role earn between $76,200.00 and $119,300.00 per year, depending on experience, location, and employer.

What does a clinical operations manager do?

A clinical operations manager or director is a health care professional who oversees the operations of a medical facility. Their duties include meeting regularly with department heads, reading assessments of employee productivity, and managing administrative tasks, such as budgeting and billing. Qualifications for a clinical operations manager include experience in medical administration, management skills, and organizational skills. An advanced degree in public health or health administration can significantly improve your job opportunities.

What is the difference between Clinical Operations Manager vs Clinical Research Coordinator?

AspectClinical Operations ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, management experienceBachelor's degree in health or life sciences, research training
Work EnvironmentOversees multiple clinical trials, manages teamsAssists with daily trial activities, data collection
Employer & IndustryPharmaceutical companies, CROs, hospitalsResearch institutions, hospitals, clinical sites

The Clinical Operations Manager focuses on overseeing entire clinical trial operations, managing teams, and ensuring compliance. In contrast, the Clinical Research Coordinator handles the day-to-day activities at trial sites, such as patient recruitment and data collection. Both roles require related credentials and work within the clinical research industry, but their responsibilities and scope differ significantly.

How much do clinical operations managers make?

Clinical operations managers in the US typically earn between $80,000 and $130,000 annually, with the median salary around $105,000. Compensation varies based on experience, location, and the size of the organization, and often includes benefits such as health insurance and bonuses.

What are the key skills and qualifications needed to thrive as a clinical operations manager, and why are they important?

To thrive as a Clinical Operations Manager, you need expertise in clinical trial management, regulatory compliance, and healthcare operations, usually supported by a degree in a health-related field and relevant experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as ACRP or SOCRA are commonly required. Strong leadership, problem-solving abilities, and effective communication are essential soft skills for this role. These skills ensure efficient trial execution, regulatory adherence, and successful coordination across teams and stakeholders.

What are the main challenges clinical operations managers face when overseeing multiple clinical trials simultaneously?

Clinical Operations Managers often juggle several clinical trials at once, which can present challenges such as maintaining consistent quality across studies, ensuring timely patient recruitment, and managing diverse teams. They must coordinate with cross-functional departments, address regulatory compliance, and troubleshoot unforeseen issues, all while staying on schedule and within budget. Effective organizational skills, proactive communication, and adaptability are essential for overcoming these challenges and ensuring successful trial outcomes.

What is a clinical operations manager?

Clinical Operations Managers are professionals responsible for overseeing the day-to-day administrative and operational functions of clinical trials or healthcare facilities. They ensure that clinical protocols are followed, resources are efficiently allocated, and regulatory compliance is maintained. These managers coordinate between healthcare staff, researchers, and external partners to facilitate smooth clinical operations and high-quality patient care. Their role is essential in ensuring that clinical services or trials are delivered effectively, safely, and on schedule.
More about Clinical Operations Manager jobs
What are the most commonly searched types of Clinical Operations jobs in Colorado? The most popular types of Clinical Operations jobs in Colorado are:
What are popular job titles related to Clinical Operations Manager jobs in Colorado? For Clinical Operations Manager jobs in Colorado, the most frequently searched job titles are:
What job categories do people searching Clinical Operations Manager jobs in Colorado look for? The top searched job categories for Clinical Operations Manager jobs in Colorado are:
What cities in Colorado are hiring for Clinical Operations Manager jobs? Cities in Colorado with the most Clinical Operations Manager job openings:
Clinical Operations Manager jobs near you
Infographic showing various Clinical Operations Manager job openings in Colorado as of August 2026, with employment types broken down into 85% Full Time, 12% Part Time, 1% Temporary, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $103,090 per year, or $49.6 per hour.

Clinical Operations Manager II

CPC Clinical Research

Aurora, CO • On-site

$71K - $88K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 16 days ago

Job description

We are looking for an experienced Clinical Operations Manager II to join our team!
Are you well organized, but adaptable to unexpected changes? Someone who is able to see the bigger picture, without losing sight of the day-to-day tasks? If the answer is yes, keep reading!
This role serves as the primary point of contact for industry sponsored clinical trials, Endpoint and Specialty Services activities and also provides operational support for biostatistics and programming deliverables.
Remote candidates are welcome to apply.
In this position you will:
  • Oversee clinical operations management activities.
  • Define and monitor project scope, timelines and deliverables from project initiation to close-out.
  • Identify project-specific training for team members and notify appropriate designee to ensure completion and filing of training documentation.
  • Oversee trial-related activities.
  • Track and approve vendor payments.
  • Provide expert advice in the design, writing and/or review of all project-related essential documents including protocols, project management plans, case report forms, statistical analysis plans, project management plans, ICF templates, study procedure manuals, source documents, site newsletters, study reports, resource tools, essential documents, monitoring plans and report templates.
  • Develop and manage multidisciplinary project team members. Organize, plan for, and produce minutes for project team meetings.
  • Ensure the overall quality of project services and deliverables.
  • Provide necessary updates and reports to the sponsor as outlined by the contract.
  • Plan and oversee the execution of investigator meetings as contracted.
  • Work with the Business Development team on budgets, proposals and change orders.
  • Ensure both CPC and sponsor are aware of and in agreement on any change in project scope that has a financial or resource impact.
  • Provide Head of Trial Master File scope of services to enable him/her to establish and maintain Trial Master Files (TMFs) and project document files, both electronic and paper.
  • Adhere to local, federal and international regulations, guidelines and CPC Policies, Standard Operating Procedures (SOPs) and Work Instructions (WIs). Use appropriate discretion to proactively identify when there is a need to deviate from policies, procedures or plans and ensure deviations are appropriately documented.
  • Define and monitor Endpoint and Specialty Services scope, timelines and deliverables from project initiation to closeout with assistance from study assigned Clinical Operations Manager and the Head of Endpoint and Specialty Services.
  • Manage contracted deliverables for external committees (e.g. data safety monitoring boards, clinical endpoint committees), including but not limited to meeting scheduling, generation of meeting minutes and distribution of meeting materials.
  • Oversee SAE process and assure execution of safety plans.
  • Accurately track receipt, entry, upload and the processing of photos, acetate tracings, and other source documents submitted from sites.
  • Contact appropriate individuals (e.g., study site staff or study site Clinical Research Associate) regarding incomplete, inaccurate, or missing photos, acetate tracings, and other Endpoint and Specialty Services Core Lab documents as required by the project.
  • Oversee timely and accurate entry and cleaning of data for all study databases; maintain and file data management documentation as required.
  • Provide feedback to study sites on tracing and quality issues, as required by project.
  • Manage and conduct Endpoint and Specialty Services CPC Core Lab activities.
  • Provide operational support for the biostatistics and programming deliverables.

Here's what you will need to bring to the table:
  • Nursing or BA/BS in a scientific field (or equivalent knowledge/experience).
  • 4 years of experience in a clinical research setting, preferably with at least 2 years of project/operations management experience in clinical research.
  • Demonstrated ability to adequately manage all facets of a clinical trial with minimal direction.
  • Thorough knowledge of the Good Clinical Practice guidelines and applicable FDA and ICH regulations for conducting clinical drug trials.
  • Proficiency in Microsoft Office, particularly Outlook, Word and Excel.
  • Excellent communication and organizational skills.
  • Great attention to detail.
  • Exemplary skills leading and managing multi-disciplinary teams in a clinical research setting.
  • Ability to organize, instruct and oversee project staff, while promoting group effort and achievement.
  • Ability to adapt quickly to new situations, manage conflicts and resolve problems effectively.
  • Willingness to travel 20-25%.

Note: Viable applicants will be required to pass a background and education verification check.
Targeted Compensation: $71,840 - $88,004 annually
Deadline to Apply: September 1, 2026
About CPC:
CPC is an academic research organization that offers full service clinical trial design, oversight, and management with rapid access to Key Opinion Leaders in a variety of therapeutic areas. With over 35 years of experience, CPC has provided services to over 150 clinical trials in a variety of indications, with an emphasis on cardiovascular, wound healing, diabetes and more.
CPC has expertise in managing clinical trials from a variety of funding sources including Industry, NIH, and Investigator Initiated trials.
CPC Community Health focuses on innovative programs that reach into communities to help people find effective ways to become active, empowered and healthy. http://www.cpccommunityhealth.org/
CPC offers:
  • Comprehensive benefits package (medical, dental, vision, life, STD, LTD etc.)
  • Matching 401(k) plan (dollar for dollar up to 4% of your eligible compensation, fully vested immediately)
  • 11 paid holidays
  • 15 - 25 vacation days based on years of service
  • Paid sick time (2.67 hours accrued bi-weekly up to a maximum of 80 hours)
  • Monthly fun events (e.g. team building activities, games, charitable events, potlucks, picnics)
  • Flexible and remote work schedules

An Equal Opportunity Employer
CPC is dedicated to the principles of equal employment opportunity (EEO). CPC prohibits unlawful discrimination against applicants or employees on the basis of age 40 and over, race (including traits historically associated with race, such as hair texture and length, protective hairstyles), sex, sexual orientation, gender identity, gender expression, color, religion, creed, national origin, ancestry, disability, military status, genetic information, marital status, or any other status protected by applicable state or local law. It is our intention that all qualified applicants are given equal opportunity and that selection decisions be based on job-related factors.
Applicants with disabilities may be entitled to reasonable accommodation under the Americans with Disabilities Act (ADA) and certain state or local laws. If you need assistance, please email our Human Resources team at careers@cpcmed.org.

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