1

Ngs Library Preparation Jobs (NOW HIRING)

With some supervision, design and execute low to moderate complexity experimental workflows, including cfDNA extraction, library preparation for next-generation sequencing (NGS) using both manual and ...

New

Extensive hands-on laboratory experience with nucleic acid and DNA/RNA molecular biology techniques, including extractions, PCR, NGS library preparation, hybrid capture, and DNA quantitation ...

Be Seen First

Prepare libraries for next-generation sequencing, carefully following established protocols. * Operate and maintain NGS instruments and related lab equipment. * Implement quality control procedures ...

... NGS library preparation, Illumina and PacBio data acquisition and QC to support drug discovery activities * At least 6 years of experience in drug discovery or development in a pre-clinical setting ...

... NGS library preparation, Illumina and PacBio data acquisition and QC to support drug discovery activities * At least 6 years of experience in drug discovery or development in a pre-clinical setting ...

Strong understanding of the chemistry underlying nucleic acid extraction, PCR, NGS library preparation, and hybrid capture technologies * Must be able to independently design and execute experiments ...

Be Seen First

Prepare libraries for next-generation sequencing, carefully following established protocols. * Operate and maintain NGS instruments and related lab equipment. * Implement quality control procedures ...

Showing results 41-60

Ngs Library Preparation information

See salary details

$9

$20

$33

How much do ngs library preparation jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for ngs library preparation in the United States is $20.51, according to ZipRecruiter salary data. Most workers in this role earn between $15.87 and $24.04 per hour, depending on experience, location, and employer.

What is NGS library preparation?

NGS library preparation is a crucial step in the next-generation sequencing (NGS) workflow. It involves preparing DNA or RNA samples so they are compatible with sequencing platforms, usually by fragmenting the nucleic acids, adding adapters, and amplifying the resulting fragments. This process enables the sequencing machine to accurately read and analyze genetic information. Proper library preparation is essential for achieving high-quality sequencing data and reliable results.

What are some common challenges faced during NGS library preparation, and how can they be addressed?

One common challenge in NGS library preparation is maintaining sample quality and integrity, as degraded or contaminated samples can compromise sequencing results. Another frequent issue is achieving consistent and efficient adapter ligation, which is crucial for successful downstream analysis. To address these, it's important to follow standardized protocols meticulously, use high-quality reagents, and incorporate quality control steps such as quantification and fragment analysis. Collaborating closely with bioinformaticians and other lab team members can also help troubleshoot issues early and optimize workflows for best results.

What are the key skills and qualifications needed to thrive as an NGS library preparation specialist, and why are they important?

To excel in NGS Library Preparation, you need a solid background in molecular biology, experience with DNA/RNA extraction, and typically a bachelor's or higher degree in a life science field. Familiarity with sequencing platforms (such as Illumina or Ion Torrent), lab automation systems, and quality control instruments is essential. Attention to detail, strong organizational skills, and effective teamwork are vital soft skills for this role. These competencies ensure the accurate and efficient preparation of high-quality libraries, which is critical for reliable sequencing results and downstream analyses.

What is the difference between Ngs Library Preparation vs Ngs Sequencing Technician?

AspectNgs Library PreparationNgs Sequencing Technician
Primary RolePreparing DNA/RNA samples for sequencing, including library construction and quality controlOperating sequencing instruments, running sequencing runs, and troubleshooting
Required SkillsSample prep, pipetting, library QC, knowledge of sequencing protocolsInstrument operation, data collection, basic troubleshooting
Work EnvironmentLaboratory setting focused on sample prepLaboratory or sequencing facility operating sequencing machines
CertificationsOften requires molecular biology or lab technician certificationsTypically requires technical training in sequencing platforms

While Ngs Library Preparation involves preparing samples for sequencing, Ngs Sequencing Technicians focus on running and maintaining sequencing instruments. Both roles are essential in genomics workflows but differ in responsibilities and skill sets.

More about Ngs Library Preparation jobs

What cities are hiring for Ngs Library Preparation jobs?

Cities with the most Ngs Library Preparation job openings:

What states have the most Ngs Library Preparation jobs?

States with the most job openings for Ngs Library Preparation jobs include:

Infographic showing various Ngs Library Preparation job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 76% Full Time, 21% Part Time, 1% Temporary, and 1% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $42,667 per year, or $20.5 per hour.

Research Associate II - Integrative Genomics Core

City of Hope

Duarte, CA • On-site

Full-time

Re-posted 11 days ago


City Of Hope rating

8.4

Company rating: 8.4 out of 10

Based on 90 frontline employees who took The Breakroom Quiz

23rd of 887 rated healthcare providers


Job description

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

We are seeking a highly motivated Research Assistant II to join the Integrative Genomics Core. You will support a wide range of genomics workflows, including next-generation sequencing (NGS) library preparation, nucleic acid extraction, and quality control processes.

The Integrative Genomics Core provides comprehensive genomics services to support cutting-edge biomedical research. Leveraging advanced platforms such as Illumina, PacBio, Nanopore, and 10x Genomics, the core enables a broad range of genomic and epigenomic applications. These technologies empower investigators to explore complex biological systems, from cancer genomics to translational and precision medicine studies, within a highly collaborative, service-oriented environment.

As a successful candidate, you will:

·         Perform DNA and RNA extraction, quantification, and quality control

·         Prepare libraries for next-generation sequencing using Illumina, PacBio (SMRT sequencing), and 10x Genomics platforms

·         Execute high-throughput workflows with attention to consistency and quality

·         Track samples and metadata using laboratory information management systems FileMaker

·         Maintain accurate and detailed laboratory records in accordance with core facility standards

·         Assist in method development, optimization, and validation of new genomics workflows under supervision of core scientists

·         Communicate effectively with core scientists regarding sample requirements, project status, and results

Your qualifications should include:

·         Bachelor’s degree in molecular biology, Genetics, or related field.  Master’s degree preferred.

·         2+ years of related experience in molecular biology or genomics with a Bachelor’s degree or 1+ year related experience with a Master’s degree.

·         Experience with standard molecular biology techniques (PCR, qPCR, nucleic acid handling)

·         2+ years of Direct experience with next-generation sequencing library preparation is preferred

·         Familiarity with Illumina sequencing platforms.

·         Experience with long-read sequencing (PacBio) and/or single-cell or spatial genomics workflows (10x Genomics)

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.  

To learn more about our Comprehensive Benefits, please CLICK HERE.


What City Of Hope employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


City of Hope logo

About City of Hope

Sourced by ZipRecruiter

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases. Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hopes translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hopes specialized cancer expertise. City of Hope is ranked among the nations Best Hospitals in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

Industry

Hospitals

Company size

1,001 - 5,000 Employees

Headquarters location

Duarte, CA, US

Year founded

1913