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Ngs Library Preparation Jobs (NOW HIRING)

Roche

Scientist II

Pleasanton, CA · On-site

As an R&D Scientist in our NGS Library Preparation and Target Enrichment team, you will be a key player in executing sample preparation workflows. You will work within a dynamic environment dedicated ...

Advanced Software Talent

Scientist II

Santa Clara, CA · On-site

Experience with PCR, qPCR, nucleic acid extraction, and NGS library preparation * Strong data analysis, technical documentation, and organizational skills * Ability to work effectively in a ...

Real Soft, Inc.

Biologist (3-5 years)

Boston, MA · On-site

... NGS library preparation/QC, and qPCR. • Strong background in NGS technologies and their applications, including quantification, sequencing, and data QC (preferably Illumina). Direct experience with ...

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Ngs Library Preparation information

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How much do ngs library preparation jobs pay per hour?

As of Jun 9, 2026, the average hourly pay for ngs library preparation in the United States is $20.51, according to ZipRecruiter salary data. Most workers in this role earn between $15.87 and $24.04 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as an NGS Library Preparation Specialist, and why are they important?

To excel in NGS Library Preparation, you need a solid background in molecular biology, experience with DNA/RNA extraction, and typically a bachelor's or higher degree in a life science field. Familiarity with sequencing platforms (such as Illumina or Ion Torrent), lab automation systems, and quality control instruments is essential. Attention to detail, strong organizational skills, and effective teamwork are vital soft skills for this role. These competencies ensure the accurate and efficient preparation of high-quality libraries, which is critical for reliable sequencing results and downstream analyses.

What are some common challenges faced during NGS library preparation, and how can they be addressed?

One common challenge in NGS library preparation is maintaining sample quality and integrity, as degraded or contaminated samples can compromise sequencing results. Another frequent issue is achieving consistent and efficient adapter ligation, which is crucial for successful downstream analysis. To address these, it's important to follow standardized protocols meticulously, use high-quality reagents, and incorporate quality control steps such as quantification and fragment analysis. Collaborating closely with bioinformaticians and other lab team members can also help troubleshoot issues early and optimize workflows for best results.

What is the difference between Ngs Library Preparation vs Ngs Sequencing Technician?

AspectNgs Library PreparationNgs Sequencing Technician
Primary RolePreparing DNA/RNA samples for sequencing, including library construction and quality controlOperating sequencing instruments, running sequencing runs, and troubleshooting
Required SkillsSample prep, pipetting, library QC, knowledge of sequencing protocolsInstrument operation, data collection, basic troubleshooting
Work EnvironmentLaboratory setting focused on sample prepLaboratory or sequencing facility operating sequencing machines
CertificationsOften requires molecular biology or lab technician certificationsTypically requires technical training in sequencing platforms

While Ngs Library Preparation involves preparing samples for sequencing, Ngs Sequencing Technicians focus on running and maintaining sequencing instruments. Both roles are essential in genomics workflows but differ in responsibilities and skill sets.

What is NGS library preparation?

NGS library preparation is a crucial step in the next-generation sequencing (NGS) workflow. It involves preparing DNA or RNA samples so they are compatible with sequencing platforms, usually by fragmenting the nucleic acids, adding adapters, and amplifying the resulting fragments. This process enables the sequencing machine to accurately read and analyze genetic information. Proper library preparation is essential for achieving high-quality sequencing data and reliable results.
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Ngs Library Preparation jobs near you
Infographic showing various Ngs Library Preparation job openings in the United States as of May 2026, with employment types broken down into 99% Full Time, and 1% Temporary. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $42,667 per year, or $20.5 per hour.

Scientist II

Roche

Pleasanton, CA • On-site

Full-time

This job post has expired today. Applications are no longer accepted.

Roche rating

9.2

Company rating: 9.2 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

3rd of 71 rated pharmaceutical

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come.

Creating a world where we all have more time with the people we love.

That's what makes us Roche.

As an R&D Scientist in our NGS Library Preparation and Target Enrichment team, you will be a key player in executing sample preparation workflows. You will work within a dynamic environment dedicated to advancing molecular biology research and contributing to innovative development efforts. This is an opportunity to thrive in a collaborative team that values technical excellence and scientific curiosity.

The Opportunity

  • Execute NGS library preparation from diverse sample types using various construction methods.

  • Perform DNA and RNA extraction from biological samples, optimizing protocols for high yield and purity.

  • Quantify nucleic acids accurately using instruments like Qubit and NanoDrop.

  • Operate and troubleshoot sequencing platforms for routine laboratory runs.

  • Conduct quality control for nucleic acids and libraries utilizing Agilent TapeStation.

  • Maintain precise experimental records in laboratory notebooks and digital formats.

  • Analyze experimental data to contribute to technical reports and team presentations.

  • Collaborate with cross-functional team members on experimental design and troubleshooting.

Who you are

  • You hold a Bachelor's or Master's degree in Molecular Biology, Genetics, Biochemistry, or a related field.

  • You possess 2-4 years of relevant laboratory experience, ideally within an industry setting.

  • You have hands-on experience with NGS library preparation protocols such as DNA-seq or RNA-seq.

  • You are proficient in PCR, nucleic acid extraction, and standard molecular biology techniques.

  • You demonstrate strong critical thinking skills and meticulous attention to detail in a fast-paced environment.

Preferred

  • Experience with advanced DNA QC instruments like Tapestation and Nanodrop.

  • Strong interpersonal skills with a proven ability to work independently or as part of a collaborative team.

  • Excellent organizational and time-management skills to meet project timelines.

Relocation benefits are not available for this posting.

The expected salary range for this position based on the primary location of Pleasanton is 68 900,00 - 106 000,00 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.


Let's build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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