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Ngs Library Preparation Jobs in Texas (NOW HIRING)

Execute NGS Workflows: Perform high-throughput Next-Generation Sequencing (NGS) library preparation and sample quality control (QC) protocols. * Operate Advanced Automation: Run, maintain, and ...

With some supervision, design and execute low to moderate complexity experimental workflows, including cfDNA extraction, library preparation for next-generation sequencing (NGS) using both manual and ...

Including but not limited to molecular diagnostic techniques such as DNA extraction, PCR set up, liquid handler operations, or NGS library preparation and sequencing. * Demonstrates strong problem ...

Senior Research Associate

Austin, TX · On-site

$69K - $87K/yr

Hands-on experience with NGS library preparation and Illumina sequencing platforms is highly preferred * Experience in a regulatory environment under IVD, CLIA/CAP is highly desired * Experience in ...

Background in NGS and/or clinical laboratories (e.g., extraction, library preparation, or sequencing workflows). * Hands-on experience programming and operating liquid handlers-especially Tecan ...

Ngs Library Preparation information

What is NGS library preparation?

NGS library preparation is a crucial step in the next-generation sequencing (NGS) workflow. It involves preparing DNA or RNA samples so they are compatible with sequencing platforms, usually by fragmenting the nucleic acids, adding adapters, and amplifying the resulting fragments. This process enables the sequencing machine to accurately read and analyze genetic information. Proper library preparation is essential for achieving high-quality sequencing data and reliable results.

What are some common challenges faced during NGS library preparation, and how can they be addressed?

One common challenge in NGS library preparation is maintaining sample quality and integrity, as degraded or contaminated samples can compromise sequencing results. Another frequent issue is achieving consistent and efficient adapter ligation, which is crucial for successful downstream analysis. To address these, it's important to follow standardized protocols meticulously, use high-quality reagents, and incorporate quality control steps such as quantification and fragment analysis. Collaborating closely with bioinformaticians and other lab team members can also help troubleshoot issues early and optimize workflows for best results.

What are the key skills and qualifications needed to thrive as an NGS library preparation specialist, and why are they important?

To excel in NGS Library Preparation, you need a solid background in molecular biology, experience with DNA/RNA extraction, and typically a bachelor's or higher degree in a life science field. Familiarity with sequencing platforms (such as Illumina or Ion Torrent), lab automation systems, and quality control instruments is essential. Attention to detail, strong organizational skills, and effective teamwork are vital soft skills for this role. These competencies ensure the accurate and efficient preparation of high-quality libraries, which is critical for reliable sequencing results and downstream analyses.

What is the difference between Ngs Library Preparation vs Ngs Sequencing Technician?

AspectNgs Library PreparationNgs Sequencing Technician
Primary RolePreparing DNA/RNA samples for sequencing, including library construction and quality controlOperating sequencing instruments, running sequencing runs, and troubleshooting
Required SkillsSample prep, pipetting, library QC, knowledge of sequencing protocolsInstrument operation, data collection, basic troubleshooting
Work EnvironmentLaboratory setting focused on sample prepLaboratory or sequencing facility operating sequencing machines
CertificationsOften requires molecular biology or lab technician certificationsTypically requires technical training in sequencing platforms

While Ngs Library Preparation involves preparing samples for sequencing, Ngs Sequencing Technicians focus on running and maintaining sequencing instruments. Both roles are essential in genomics workflows but differ in responsibilities and skill sets.

What cities in Texas are hiring for Ngs Library Preparation jobs?

Cities in Texas with the most Ngs Library Preparation job openings:

Research Associate

Tamus

College Station, TX • On-site

$3.7K/mo

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 8 days ago


Job description

Job Title

Research Associate

Agency

Texas A&M Agrilife Research

Department

Genomics & Bioinformatics Services

Proposed Minimum Salary

$3,750.00 monthly

Job Location

College Station, Texas

Job Type

Staff

Job Description

About Texas A&M AgriLife

Texas A&M AgriLife is comprised of the following Texas A&M University System members:

  • Texas A&M AgriLife Extension Service
  • Texas A&M AgriLife Research
  • College of Agriculture and Life Sciences at Texas A&M University
  • Texas A&M Forest Service
  • Texas A&M Veterinary Medical Diagnostic Laboratory

As the nation's largest most comprehensive agriculture program, Texas A&M AgriLife brings together a college and four state agencies focused on agriculture and life sciences within The Texas A&M University System. With over 5,000 employees and a presence in every county across the state, Texas A&M AgriLife is uniquely positioned to improve lives, environments and the Texas economy through education, research, extension and service.

Click here to learn more about how you can be a part of AgriLife and make a difference in the world!

Position Information

Texas A&M AgriLife Genomics and Bioinformatics Service (TxGen), a multimillion-dollar research unit within Texas A&M AgriLife Research, has grown over the last 16 years to be one of the leading Agriculture-focused sequencing facilities in the world, with several world firsts to our name. Come join an extraordinary team of AgriLife scientists with vast and various backgrounds. TxGen has worked with scientists in 45 countries, has completed thousands of projects, and maintains strong collaborations with several of the top sequencing and biotechnology companies to advance agricultural and biological research around the world. We are seeking a highly detail-oriented candidate with professional laboratory experience executing Next-Generation Sequencing (NGS) library preparation and quality control (QC). Experience with automated liquid handlers and short-read sequencing platforms is highly desirable. As a specialized member of a close-knit group, you will be exposed to all aspects of our facility operations. In this role, you will perform skilled, independent laboratory procedures and technical troubleshooting within a high-throughput research service environment. You will be responsible for executing laboratory Standard Operating Procedures (SOPs), maintaining meticulous documentation, and ensuring data integrity across complex genomic workflows.

Responsibilities:

  • Execute NGS Workflows: Perform high-throughput Next-Generation Sequencing (NGS) library preparation and sample quality control (QC) protocols.
  • Operate Advanced Automation: Run, maintain, and troubleshoot precision laboratory instrumentation, automated liquid handlers, and sequencing platforms.
  • Manage Data & Samples: Handle sample intake, log processing steps into the laboratory information management system (LIMS), and verify sample data integrity.
  • Generate Client Reports: Compile specialized metadata, organize experimental results, and translate laboratory data into clear, accurate technical reports for clients.
  • Maintain Quality Standards: Follow established laboratory Standard Operating Procedures (SOPs), institutional biosafety guidelines, and quality control metrics.
  • Perform Other Duties: Execute related laboratory and administrative tasks as assigned to support facility operations.

Qualifications

Required Education:

  • Bachelor's degree in Biology, Genetics, Chemistry, Biochemistry, Molecular Biology, or a relevant scientific field, or equivalent combination of education and experience.

Required Experience:

  • Two (2) years of experience performing high-throughput NGS library preparation and associated quality control procedures.

Required Knowledge, Skills, and Abilities:

  • Demonstrated proficiency in high-throughput NGS library preparation workflows.
  • Experience performing molecular biology quality control (QC), including nucleic acid quantification and fragment analysis.
  • Experience working with automated liquid handling systems or the ability to become proficient quickly.
  • Knowledge of laboratory safety protocols and standard scientific instrumentation.
  • Exceptional attention to detail and precision under time-sensitive service deadlines.
  • Strong verbal and written communication skills.
  • Ability to work independently and collaboratively in a fast-paced laboratory environment.

Physical Requirements:

  • Ability to stand for extended periods.
  • Ability to lift laboratory supplies weighing up to 25 pounds.
  • Manual dexterity sufficient to perform repetitive pipetting and fine laboratory procedures.
  • Ability to distinguish colors used in laboratory assays and instrumentation.

Preferred Qualifications:

  • Experience operating automated liquid handling systems.
  • Experience with Illumina sequencing platforms.
  • Experience working in a CLIA, GLP, ISO, or research service laboratory.
  • Experience using a Laboratory Information Management System (LIMS).

Why Work at Texas A&M AgriLife?

When you choose toworkfor Texas A&M AgriLife, you become part of an organization that is an established leader in agriculture and life sciences with a wide range of capabilities to meet the needs of our statewide, national, and international constituents.

In addition, Texas A&M AgriLife offers a comprehensive benefit package including the following:

  • Health, dental, vision, life and long-term disability insurance with Texas A&M AgriLife contributing to employee health and basic life premiums
  • 12-15 days of annual paid holidays
  • Up to eight hours of paid sick leaveand at leasteight hours of paid vacation each month
  • Automatic enrollment in theTeacher Retirement System of Texas
  • Employee Wellness Initiative for Texas A&M AgriLife

Applicant Instructions

Applications received by Texas A&M AgriLife must either have all job application data entered or a resume attached. Failure to provide all job application data or a complete resume could result in an invalid submission and a rejected application. We encourage all applicants to upload a resume or use a LinkedIn profile to prepopulate the online application.

All positions are security-sensitive. Applicants are subject to a criminal history investigation, and employment is contingent upon the institution's verification of credentials and/or other information required by the institution's procedures, including the completion of the criminal history check.

Equal Opportunity/Veterans/Disability Employer.