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Manager Of Clinical Operations Jobs (NOW HIRING)

Program Management • In charge of establishing, updating and managing integrated development ... clinical operations, regulatory affairs, quality, and manufacturing. • Demonstrated success ...

Clinical Operations Manager

Buffalo, MN · On-site

$92K - $124K/yr

What You'll Do The Clinical Operations Manager works in collaboration with the Operations Manager ... Fostering a culture of accountability and excellence by ensuring compliance with all regulatory ...

Manager, Clinical Operations

Durham, NC · On-site

$86K - $216K/yr

Participate in the allocation of resources to clinical research projects by assigning staff to ... clinical operations management. May collaborate with other clinical teams and other functional ...

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Manager Of Clinical Operations information

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$35K

$98K

$186.5K

How much do manager of clinical operations jobs pay per year?

As of Sep 12, 2026, the average yearly pay for manager of clinical operations in the United States is $98,039.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $113,500.00 per year, depending on experience, location, and employer.

What does a manager of clinical operations do?

A Manager of Clinical Operations oversees the daily activities of clinical research or healthcare departments to ensure smooth and efficient operations. They are responsible for managing staff, budgets, compliance with regulatory requirements, and the implementation of clinical protocols. Their role often includes coordinating with different departments, monitoring project timelines, and ensuring the quality and safety of patient care or research outcomes. This position requires strong leadership, organizational, and communication skills.

What are the key skills and qualifications needed to thrive as a manager of clinical operations?

To thrive as a Manager of Clinical Operations, you need a strong background in healthcare management, clinical protocols, and regulatory compliance, often supported by a degree in healthcare administration or a clinical field. Familiarity with clinical trial management systems (CTMS), electronic health records (EHRs), and relevant certifications such as CCRA or CCRP are commonly required. Leadership, problem-solving, and effective communication skills are essential for leading teams and coordinating multiple stakeholders. These skills are crucial for ensuring efficient clinical workflows, regulatory adherence, and high-quality patient care.

What are some typical challenges faced by a manager of clinical operations, and how can candidates prepare to address them?

Managers of Clinical Operations often encounter challenges such as balancing regulatory compliance with efficient trial execution, coordinating across multidisciplinary teams, and adapting to shifting project timelines or budgets. To succeed, candidates should develop strong organizational and communication skills, stay updated on industry regulations, and foster collaborative relationships with clinical staff, investigators, and external partners. Proactively learning about change management and resource allocation can also help candidates navigate these complexities effectively.

What is the difference between Manager Of Clinical Operations vs Clinical Project Manager?

AspectManager Of Clinical OperationsClinical Project Manager
ResponsibilitiesOversees multiple clinical trials, manages teams, ensures compliance, and coordinates with departmentsManages specific clinical projects, handles timelines, budgets, and project deliverables
Required CredentialsBachelor's or higher in life sciences, often with experience in clinical operationsBachelor's or higher, often with project management certifications
Work EnvironmentCorporate or pharmaceutical company, overseeing multiple projectsProject-specific teams within clinical research settings
Industry UsageCommon in pharmaceutical, biotech, and healthcare companiesCommon in clinical research organizations and pharmaceutical companies

The Manager Of Clinical Operations focuses on overseeing the broader clinical operations and multiple trials, while the Clinical Project Manager concentrates on managing individual clinical projects. Both roles require strong knowledge of clinical processes, but their scope and responsibilities differ significantly.

How much do manager of clinical operations make in the US?

The average salary for a manager of clinical operations in the US is approximately $100,000 to $130,000 per year, depending on experience, location, and the size of the organization. Many roles also include benefits such as bonuses, health insurance, and professional development opportunities.
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Infographic showing various Manager Of Clinical Operations job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $98,039 per year, or $47.1 per hour.

Director, Clinical Operations

Los Angeles, CA • Hybrid

COPE Health Solutions
Business Management Consulting • 51 - 200 employees

Full-time

Re-posted 7 days ago


Job description

The Clinical Operations Director is a senior leadership role responsible for providing strategic direction, operational oversight, and performance management of clinical programs and services. This position requires a forward-thinking leader with a comprehensive understanding of clinical operations, regulatory compliance, and quality improvement. The Clinical Operations Director plays a critical role in ensuring high-quality patient care, operational efficiency, and alignment with organizational goals.
FLSA Status
Exempt
Salary Range
$172,100 – $211,575
Reports To
Principal and Executive Vice President
Direct Reports
LVN, LCSW, LMSW (clinical team) 
Location
Hybrid in LA Office
Travel
Up to 50%
Work Type
Regular
Schedule
Full Time
 

Key Duties and Responsibilities

· Provide strategic oversight for the planning, implementation, and evaluation of clinical programs from initiation through completion.

· Develop and execute operational strategies to enhance clinical performance, efficiency, and quality of care.

· Ensure clinical services and team practices are conducted in accordance with ethical standards, organizational policies, and all regulatory and accreditation requirements.

· Collaborate with providers, nursing staff, and non-clinical leadership to implement policies, strengthen clinical workflows, and improve service delivery.

· Coordinate across departments to ensure clinical programs operate effectively, efficiently, and in alignment with organizational objectives.

· Lead and manage clinical operations staff, including recruitment, onboarding, training, coaching, and performance management.

· Oversee clinical quality initiatives, including audits, incident reporting, root cause analyses, and infection prevention and control programs.

· Develop and implement staff education and training initiatives to ensure adherence to clinical standards, best practices, and regulatory requirements.

· Monitor and analyze quality metrics, dashboards, and performance data to identify trends, address gaps in care, and improve clinical outcomes.

· Build and maintain collaborative relationships with external partners, including community-based organizations, health plans, regulatory bodies, and healthcare providers.

· Ensure readiness for regulatory reviews, audits, and accreditation processes.

· Support a culture of accountability, continuous improvement, and patient-centered care.

Qualifications

· Active Registered Nurse (RN) license required.

· Bachelor’s degree in Nursing (BSN) or a related healthcare field required.

· Master’s degree in Nursing (MSN), Healthcare Administration (MHA), Public Health (MPH), or related field preferred.

· Minimum of 5–10 years of progressive clinical experience, including significant leadership or management experience in clinical operations, quality assurance, or healthcare program management.

· Strong knowledge of Medicare and Medicaid regulations, accreditation standards, and healthcare risk management practices.

· Demonstrated leadership, analytical, communication, and problem-solving skills.

· Proven ability to manage multiple priorities and projects in a fast-paced, high-demand healthcare environment.

· Strong commitment to quality, compliance, and organizational success.

· Ability to work collaboratively across multidisciplinary teams.

· Flexibility to work varied hours, including evenings or weekends as needed, and willingness to travel when required.

Working Conditions

· Office and hybrid working environment

· 80% of travel requirements for meetings, site visits, satellite offices as required.

COPE Health Solutions reserves the right to modify the job description based upon its needs and may require the employee to perform functions beyond those mentioned above. Neither this job description nor any other communication creates an employment contract between the Company and the employee.

Equal Employment

Our culture encourages individual development, embraces an inclusive environment, rewards innovative excellence. COPE Health Solutions values diversity, inclusion, and equity as matters of fairness and effectiveness. We are committed to hiring and retaining a staff that reflects the diversity of the communities we serve, fostering an inclusive working environment where staff of all backgrounds feel welcomed and engaged.

COPE Health Solutions is an Equal Opportunity Employer and encourages applications from individuals underrepresented in the medical sector, including people of color, and persons with non-traditional work and educational experience. All who believe they meet the stated qualifications are invited to apply.

Benefits:

As a firm passionate about health care, we’re deeply committed to the health and wellness of our own team members. We offer comprehensive, affordable insurance plans for our team and their families, and a host of other unique benefits, such as a yearly stipend for wellness-related activities and a paid parental leave program. You can learn more about our benefits offerings here: https://copehealthsolutions.com/careers/why-cope-health-solutions/.

About COPE Health Solutions COPE Health Solutions is a national tech-enabled services firm powering success for health plans and for providers in risk arrangements. Our comprehensive NCQA certified population health management platform and highly experienced team brings deep expertise, experience, proven tools, and processes to improve financial performance and quality outcomes for all types of payers and providers. CHS de-risks the roadmap to advanced value-based payment and improves quality and financial performance for providers, health plans and self-insured employers. For more information, visit CopeHealthSolutions.com.

To Apply:

To apply for this position or for more information about COPE Health Solutions, visit us at https://copehealthsolutions.com/careers/open-positions/.