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Manager Of Clinical Operations Jobs in Silver Spring, MD

PharmaOut

Clinical Project Manager

Gaithersburg, MD · On-site

Manage day to day activities of all aspects of clinical studies including study plans, timelines ... Maintains primary responsibility for the content of and execution on all study-related operational ...

MacroGenics

Sr. TMF Manager

Rockville, MD · On-site

$34.25 - $46.75/hr

Work with the head of clinical operations systems to ensure continuing governance with the third ... The Senior Manager of TMF Operations is responsible for all aspects of the 3rd party governance ...

REGENXBIO

Sr Clinical Project Manager

Rockville, MD · On-site

Responsible for all operational aspects and progress of clinical trial from a study planning ... Responsible for management of CTT team meetings and other internal meetings as required

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Manager Of Clinical Operations information

See Silver Spring, MD salary details

$36.2K

$101.3K

$192.8K

How much do manager of clinical operations jobs pay per year?

As of Aug 23, 2026, the average yearly pay for manager of clinical operations in Silver Spring, MD is $101,350.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,900.00 and $117,300.00 per year, depending on experience, location, and employer.

What does a manager of clinical operations do?

A Manager of Clinical Operations oversees the daily activities of clinical research or healthcare departments to ensure smooth and efficient operations. They are responsible for managing staff, budgets, compliance with regulatory requirements, and the implementation of clinical protocols. Their role often includes coordinating with different departments, monitoring project timelines, and ensuring the quality and safety of patient care or research outcomes. This position requires strong leadership, organizational, and communication skills.

What are the key skills and qualifications needed to thrive as a manager of clinical operations?

To thrive as a Manager of Clinical Operations, you need a strong background in healthcare management, clinical protocols, and regulatory compliance, often supported by a degree in healthcare administration or a clinical field. Familiarity with clinical trial management systems (CTMS), electronic health records (EHRs), and relevant certifications such as CCRA or CCRP are commonly required. Leadership, problem-solving, and effective communication skills are essential for leading teams and coordinating multiple stakeholders. These skills are crucial for ensuring efficient clinical workflows, regulatory adherence, and high-quality patient care.

What are some typical challenges faced by a manager of clinical operations, and how can candidates prepare to address them?

Managers of Clinical Operations often encounter challenges such as balancing regulatory compliance with efficient trial execution, coordinating across multidisciplinary teams, and adapting to shifting project timelines or budgets. To succeed, candidates should develop strong organizational and communication skills, stay updated on industry regulations, and foster collaborative relationships with clinical staff, investigators, and external partners. Proactively learning about change management and resource allocation can also help candidates navigate these complexities effectively.

What is the difference between Manager Of Clinical Operations vs Clinical Project Manager?

AspectManager Of Clinical OperationsClinical Project Manager
ResponsibilitiesOversees multiple clinical trials, manages teams, ensures compliance, and coordinates with departmentsManages specific clinical projects, handles timelines, budgets, and project deliverables
Required CredentialsBachelor's or higher in life sciences, often with experience in clinical operationsBachelor's or higher, often with project management certifications
Work EnvironmentCorporate or pharmaceutical company, overseeing multiple projectsProject-specific teams within clinical research settings
Industry UsageCommon in pharmaceutical, biotech, and healthcare companiesCommon in clinical research organizations and pharmaceutical companies

The Manager Of Clinical Operations focuses on overseeing the broader clinical operations and multiple trials, while the Clinical Project Manager concentrates on managing individual clinical projects. Both roles require strong knowledge of clinical processes, but their scope and responsibilities differ significantly.

How much do manager of clinical operations make in the US?

The average salary for a manager of clinical operations in the US is approximately $100,000 to $130,000 per year, depending on experience, location, and the size of the organization. Many roles also include benefits such as bonuses, health insurance, and professional development opportunities.

What are the most commonly searched types of Of Clinical Operations jobs in Silver Spring, MD?

The most popular types of Of Clinical Operations jobs in Silver Spring, MD are:

What cities near Silver Spring, MD are hiring for Manager Of Clinical Operations jobs?

Cities near Silver Spring, MD with the most Manager Of Clinical Operations job openings:

Manager Of Clinical Operations jobs near you
Infographic showing various Manager Of Clinical Operations job openings in Silver Spring, MD as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 9% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 93% Physical, 3% Hybrid, and 4% Remote job distribution, with an average salary of $101,350 per year, or $48.7 per hour.

Head of Clinical Operations ( On site role)

Precigen, Inc

Germantown, MD • On-site

Full-time

Re-posted 6 days ago

Job description

Precigen is seeking a highly motivated and skilled Head of Clinical Operations (level determined by candidate experience), to drive our clinical trial programs to develop next generation gene and cell therapies focused in immuno-oncology, autoimmune disorders, and infectious diseases. Reporting to the Head of Clinical Operations, this role is responsible for driving organizational strategy and overall execution of clinical program(s) to align with corporate objectives, collaborating with executive leadership and external stakeholders to drive the success of our clinical programs. The position will lead a high-performing Clinical Operation team to ensure work quality, timeliness and adherence to budget.

The candidate will have a strong knowledge of global regulatory guidelines, strong organization and time management skills, and demonstrate focus to output/deliverables.

DUTIES AND RESPONSIBILITIES:

  • Oversight of the execution of all clinical trials
  • Ensures all trials are conducted in accordance with applicable SOPs, ICH, GCP and other applicable regulations.
  • Responsibility for meeting timelines and the execution of clinical studies making sure deliverables, milestones, and budget parameters are met. Demonstrated ability to set and manage priorities, resources, performance targets and project initiatives in a global environment is required.
  • Manages resources and external vendors efficiently
  • Responsible for overall budget forecasting and management
  • Maintains and provides relevant and accurate information for monthly study reports (including enrollment curves, timelines, analysis of the study status and identification of potential risks) Clinical Trial material (CTM) Management, budget, and finances, change orders, contracts.
  • Provide Clinical Operations expertise in cross-functional meetings and works closely with cross functional members to ensure the quality and in accordance with Precigen SOPs and global regulatory guidelines

EDUCATION AND EXPERIENCE:

  • PhD, MD or Bachelors in medical or life science, regulatory science, or related field.
  • Strong understanding of global regulatory guidelines and processes.
  • Minimum of ten (10)+ years progressive experience in pharma/biopharma clinical operations.
  • Experience with biologics/gene therapy is preferred.

DESIRED KEY COMPETENCIES:

  • Ability to understand and execute on the company’s mission and values.
  • Exceptional organization skills with strong attention to detail.
  • Strong personal leadership and self-direction.
  • Clear communication in both oral and written form.
  • Demonstrated ability to work with and coordinate demands from multiple stakeholders.
  • Exhibition of the highest degree of ethical standards and trustworthiness.
  • Advanced skills in Microsoft Word, Adobe Acrobat Professional®, and clinical trial management systems (CTMS).