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Downstream Process Development Scientist Jobs (NOW HIRING)

Lundbeck

Downstream Development Associate II

Bothell, WA · On-site

$38 - $45/hr

... Process Science & Validation Team. The Lu-SBP team leads and supports the development of new ... Summary: Performs downstream process development experiments and supporting activities, which ...

Orano

Process Development Scientist

Plano, TX · On-site

We are seeking a highly motivated Process Development Scientist with expertise in radiopharmaceutical development to join our CMC team. The successful candidate will design, execute, and analyze ...

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How much do downstream process development scientist jobs pay per hour?

As of Jul 22, 2026, the average hourly pay for downstream process development scientist in the United States is $38.66, according to ZipRecruiter salary data. Most workers in this role earn between $28.37 and $46.15 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Downstream Process Development Scientist position, and why are they important?

To thrive as a Downstream Process Development Scientist, you need expertise in biochemistry, chemical engineering, and purification techniques, typically supported by a relevant science degree or higher. Experience with protein chromatography systems, filtration equipment, and data analysis software is highly valued, along with familiarity with GMP and regulatory requirements. Strong analytical thinking, problem-solving abilities, and effective teamwork and communication are key soft skills for this position. These competencies are crucial for optimizing manufacturing processes and ensuring the successful scale-up of biologic products in a collaborative environment.

What typical challenges might a Downstream Process Development Scientist encounter in their daily work?

Downstream Process Development Scientists often face challenges related to optimizing purification processes to achieve high yield and product purity, while maintaining efficiency and scalability. They may need to troubleshoot issues with chromatography, filtration, or product stability, sometimes under tight timelines. Working closely with cross-functional teams—including upstream development, quality control, and manufacturing—is common for resolving complex technical problems. Adaptability and continuous learning are important, as methods and equipment may evolve based on project needs and technological advancements.

What is a Downstream Process Development Scientist job?

A Downstream Process Development Scientist is responsible for developing and optimizing processes to purify biological products, such as proteins, antibodies, or vaccines, after they are produced in upstream bioprocessing. They work with techniques like filtration, chromatography, and centrifugation to refine and scale up purification methods for manufacturing. Their role involves ensuring product quality, improving yields, and troubleshooting any processing challenges. Scientists in this field collaborate with cross-functional teams, including upstream development, analytical sciences, and manufacturing, to ensure efficient and scalable bioprocesses.

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Downstream Process Development Scientist jobs near you
Infographic showing various Downstream Process Development Scientist job openings in the United States as of July 2026, with employment types broken down into 88% Full Time, and 12% Contract. Highlights an 94% In-person, and 6% Hybrid job distribution, with an average salary of $80,420 per year, or $38.7 per hour.
Research Associate, Process Development Downstream

Research Associate, Process Development Downstream

Avid Bioservices

Tustin, CA • On-site

$58K - $73K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 15 days ago

Job description

Description
Looking to join a passionate team dedicated to developing and manufacturing life-saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes.
Your Role:
The Research Associate, Process Development Downstream will provide laboratory support for Process Development by assisting in the downstream process and/or method development. The Research Associate may be assigned various tasks within the department and outside the department as needed.
Key Responsibilities:
  • Assist in downstream process development and routine purification of antibodies and proteins. Activities include but are not limited to buffer formulation development, buffer preparation, chromatography method development and execution, and filtration process development and operation.
  • Assist in performing in-process and/or routine analytical assays to support downstream development effort. Assays will include protein concentration by A280, and HPLC assays.
  • Execute a process involving chromatography skid, filtration setup, and intermediate testing instruments with minimal supervision.
  • Assist in scale up and process/tech transfer of buffer preparation and downstream process.
  • Compile, analyze data, and write reports, which will be presented in Process Development group meetings or to clients as needed.
  • Experience in High throughput technologies, lab automation and/or process intensification would be advantageous, but not necessary.
  • Evaluate new technologies and/or products under guidance.
  • Perform other duties as assigned.

Minimum Qualifications:
  • B.S. degree in a Biological Science.
  • 1-2 years of relevant industry experience with demonstrated working knowledge of scientific principles.

Position Type/Expected Hours of Work:
This role is a full-time onsite position. Days and hours of work are Monday through Friday, 8:00 a.m. to 5:00 p.m. unless otherwise stated by Supervisor. The employee must also, if instructed, have the ability to work overtime and/or weekends when necessary.
Compensation:
We offer competitive compensation packages for this role, including a base salary, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.
The compensation range for this role is $58,400 - $73,000 annually depending on experience and qualifications. Additionally, we offer opportunities for career growth and development as well as a supportive and inclusive work environment.
We understand the importance of attracting and retaining top talent. The expected base pay range for this position is ($58,400 - $73,000) plus bonus and comprehensive benefits. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training. Our benefits include health, dental and vision insurance benefits to ensure your well-being.
Who you are:
  • You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
  • Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
  • You have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.
  • You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.

Physical Demands & Work Environment:
In this dynamic role, expect a blend of regular activities like sitting, standing, and walking, with occasional physically engaging tasks such as lifting objects up to 20 pounds. The work environment might expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels occasionally. However, reasonable accommodations are available to enable individuals with different abilities to perform effectively, ensuring a supportive and adaptable work setting. Your visual acuity, including close, distance, and color vision, will be essential in navigating through the diverse day-to-day demands of this position.

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