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Downstream Process Development Scientist Jobs (NOW HIRING)

Orano

Process Development Scientist

Plano, TX · On-site

We are seeking a highly motivated Process Development Scientist with expertise in radiopharmaceutical development to join our CMC team. The successful candidate will design, execute, and analyze ...

Adecco

Scientist III

Swiftwater, PA

$80/hr

Scientist III - Downstream Process Development (DSP/MSAT)Adecco Healthcare & Life Sciences is hiring for a notable global biopharmaceutical organization known for developing innovative vaccines ...

Lundbeck

Downstream Development Associate II

Bothell, WA · On-site

$38 - $45/hr

... Process Science & Validation Team. The Lu-SBP team leads and supports the development of new ... Summary: Performs downstream process development experiments and supporting activities, which ...

Lonza

Scientist II, Downstream

Houston, TX · On-site

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

Merck & Co.

Our vaccines downstream process development team develops safe, scalable, robust, cost-effective ... The candidate will be responsible for scientific/technical contributions and leadership of ...

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How much do downstream process development scientist jobs pay per hour?

As of Jun 11, 2026, the average hourly pay for downstream process development scientist in the United States is $38.66, according to ZipRecruiter salary data. Most workers in this role earn between $28.37 and $46.15 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Downstream Process Development Scientist position, and why are they important?

To thrive as a Downstream Process Development Scientist, you need expertise in biochemistry, chemical engineering, and purification techniques, typically supported by a relevant science degree or higher. Experience with protein chromatography systems, filtration equipment, and data analysis software is highly valued, along with familiarity with GMP and regulatory requirements. Strong analytical thinking, problem-solving abilities, and effective teamwork and communication are key soft skills for this position. These competencies are crucial for optimizing manufacturing processes and ensuring the successful scale-up of biologic products in a collaborative environment.

What typical challenges might a Downstream Process Development Scientist encounter in their daily work?

Downstream Process Development Scientists often face challenges related to optimizing purification processes to achieve high yield and product purity, while maintaining efficiency and scalability. They may need to troubleshoot issues with chromatography, filtration, or product stability, sometimes under tight timelines. Working closely with cross-functional teams—including upstream development, quality control, and manufacturing—is common for resolving complex technical problems. Adaptability and continuous learning are important, as methods and equipment may evolve based on project needs and technological advancements.

What is a Downstream Process Development Scientist job?

A Downstream Process Development Scientist is responsible for developing and optimizing processes to purify biological products, such as proteins, antibodies, or vaccines, after they are produced in upstream bioprocessing. They work with techniques like filtration, chromatography, and centrifugation to refine and scale up purification methods for manufacturing. Their role involves ensuring product quality, improving yields, and troubleshooting any processing challenges. Scientists in this field collaborate with cross-functional teams, including upstream development, analytical sciences, and manufacturing, to ensure efficient and scalable bioprocesses.

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Downstream Process Development Scientist jobs near you
Infographic showing various Downstream Process Development Scientist job openings in the United States as of June 2026, with employment types broken down into 4% Locum Tenens, 4% Full Time, 77% Part Time, and 15% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $80,420 per year, or $38.7 per hour.
Process Development Research Associate I/II - Downstream

Process Development Research Associate I/II - Downstream

KBI Biopharma, Inc.

Durham, NC • On-site

$55K - $75K/yr

Full-time

Posted yesterday

Job description

Position Summary

Responsible for supporting process development activities for downstream production processes, instruments and equipment.

Position Responsibilities

  • Support all downstream process development activities including execution of experiments, compilation and analysis of data and drafting of technical documents.

  • Assist in the evaluation, development and implementation of new downstream technologies leading to process improvements and efficiency of operation.

  • Assist with development of preliminary schedules along with material/personnel/equipment requirements to allow accurate and appropriate performance guarantees

  • Equipment troubleshooting and maintenance

  • General lab organization

Minimum Requirements

  • B.S. degree in biotechnology or related (or equivalent training) with 0-4 years experience or a M.S. degree with 0-2 years experience.

  • Research Associate II requires a B.S. degree and 2+ years experience or a M.S. degree.

  • Experience with downstream process development and chromatography equipment required. Excellent written and communication skills for customer service and ability to meet strict client deadlines. Flexibility of hours to support downstream processes. Knowledge of GMPs and biotechnology-derived product regulations preferred.

Salary:

Process Development Associate I: $55,000-$75,900

Process Development Associate II: $63,000-$86,900

KBI Biopharma, Inc. is an EEO/AA employer and actively seeks to diversify its work force. Therefore, all qualified applicants, regardless of race, color, national origin, religion, gender, gender identity, sexual orientation, age, disability or veteran status, are strongly encouraged to apply.

I understand that neither the completion of this application nor any other part of my consideration for employment establishes any obligation for KBI Biopharma, Inc. to hire me. If I am hired, I understand that either KBI Biopharma, Inc. or I can terminate my employment at any time and for any reason, with or without cause and without prior notice. I understand that no representative of KBI Biopharma, Inc. has the authority to make any assurance to the contrary.

I attest with my signature below that I have given to KBI Biopharma, Inc. true and complete information on this application. No requested information has been concealed. I authorize KBI Biopharma, Inc. to contact references provided for employment reference checks. If any information I have provided is untrue, or if I have concealed material information, I understand that this will constitute cause for the denial of employment or immediate dismissal.

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