Cro Manager Jobs (NOW HIRING)

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Takeda Research is constructing a Lab of Tomorrow built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost. To catalyze these efforts, Takeda is creating two complementary units: AI Research Accelerator (AIRx) and Discovery Automation & Robotics (DAR).

AIRxwill consist of a dedicated group of experienced drug hunters with the autonomy of a biotech and the resources of a leading pharmaceutical company. It is designed to incubate the future AI-powered operating models and deliver candidates to the clinic at industry leading speed and success rates.

Who are we looking for?

Can you go beyond managing a CRO relationship, developing true partnerships that can show acceleration of our programs, the development of new capabilities and executive skills to traverse the needs of an agile team in the environment of a pharmaceutical company with energy and an entrepreneurial mind-set.

Role Purpose

AIRxexecutesthe majority ofits wet-lab work externally - its speed, cost, and quality targets all depend on CROs operating as a true extension of the team. TheDirector,AIRxCRO & External Partnerships is thesingle accountableowner of all CRO relationships forAIRx.

This is not a contracting role. CROs must be actively managed with clear expectations, frequent direction-setting, real-time performance management, and direct accountability for milestones and quality. This roledrives this through daily coordination with CRO teams, regular on-site presence at key partners (including periodic visits to domestic and international CROs), and tight integration withAIRxscientific leads.

Thisroleowns the full external execution lifecycle - partner identification, contracting, data specification, and ongoing performance management - and ensures CRO outputs feedAIRxdata systems in a format ready for AI/ML decision-making. The ideal candidate brings deep CRO landscape knowledge, an established external network, and the operational rigor to run multiple parallel partnerships atAIRx'space and quality bar.This role will constructively challenge and execute operational effectiveness and be able to manage internal processes at speed and strategize sustainable approaches that scalable.

Accountabilities

Active CRO management

• Manage CROs with active oversight - notarm's-length vendor management. Set expectations, drive cadences, and hold partners directly accountable for milestones and quality.
• Maintain regular on-site presence at key CRO partners, including periodic visits to critical domestic and international partners; use site time to deepen relationships, resolve issues directly, and reinforceAIRxways of working.
• Demonstrate and continuously improve speed of services with the required quality
• Drive dailyandweekly coordination between CRO teams andAIRxscientific leads to ensure tight execution against shared milestones.
• Identifyperformance issues proactively - at the workinglevel, beforethey become escalations - and resolve in real time to protect program timelines.

Partnerselection& contracting

• Identifyand evaluate CRO partners for chemistry, biology, DMPK, and other capabilities required byAIRxprograms.
• Own contracts, SOWs, timelines, and quality standards; partner with Takeda procurement, legal, and alliancemanagementas necessary.
• Build andmaintaina preferred supplier network capable of responding atAIRx'space and quality requirements.
• Develop innovative CRO capabilities through active partnerships that drive AIRx goals

Data, budget & landscape

• Coordinate data handoffs to ensure CRO outputs are captured inAIRxdata systems (TetraScience, SAIL) in a standardized, decision-ready format suitable for AI/ML pipelines.
• Trackand manageoutsourcing spend across programs; provide budget visibility to Head ofAIRxand Program Manager.
• Monitor the external CRO and innovation landscape for new capabilities, providers, and partnership modelsthatstrengthenAIRxexecution.

Qualifications & Competencies

• Degree in life sciences or chemistry; advanced degree preferred.
• 10+ years of experience in pharmaceutical outsourcing, CRO management, or alliance management within drug discovery; biotech experiencestronglypreferred.
• Demonstrable experience in developing new capabilities and ways of working that drive innovation and accelerated outcomes with Outsourced partners.
• Deep knowledge of the CRO landscape across chemistry, biology, and DMPK capabilities;establishedpersonal network of CRO and external partner relationships.
• Proventrack recordactively managing complex,multi-CRO programs - not just contracting them - with urgency, rigor, and budget discipline.
• Hands-on, operational style; comfortable embedding in scientific team dynamics rather than managing at arm's length.
• Willingness and ability to travel domestically and internationally on a regular basis.
• Strong contract negotiation, vendor management, and performance oversight skills.
• Experience supporting AI/ML-enabled or digital drug discovery programs strongly preferred; familiarity with data standardization requirements (TetraScience, FAIR data principles) a plus.

ADDITIONAL INFORMATION

• The position will be based in Cambridge, MA. This position is currently classified as "hybrid" by Takeda's Hybrid and Remote Work policy
• Travel Requirement includes visits to critical domestic partners and quarterly visits to international partners

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

U.S. Base Salary Range:

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Job Exempt