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Systimmune

Clinical Research Associate II

Princeton, NJ · Remote

$80K - $110K/yr

The CRA II is responsible for the management and oversight of their assigned clinical study sites ... Prepare the study reference manual, including liaising with the Contract Research Organization (CRO ...

Alira Health

Summary The CRA is an important member of the Alira Health Clinical team. The CRA is highly ... Assists in set up/collection of site-specific ethics documents and site contract negotiation.

Novotech

Clinical Research Associate II

Casar, NC · On-site +1

The CRA is the primary contact between the Investigational Sites, Novotech, and Sponsor. Key ... Novotech is a global full-service clinical Contract Research Organization (CRO). At Novotech ...

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How much do contract cra jobs pay per hour?

As of Jun 17, 2026, the average hourly pay for contract cra in the United States is $41.13, according to ZipRecruiter salary data. Most workers in this role earn between $28.85 and $52.64 per hour, depending on experience, location, and employer.

What are some common challenges faced by Contract Clinical Research Associates (CRAs) and how can they effectively manage them?

Contract CRAs often juggle multiple clinical trial sites and studies, which can make prioritizing and time management especially challenging. They must adapt quickly to each sponsor's protocols and systems, often with limited onboarding. Building strong relationships with site staff and maintaining clear, consistent communication are key to overcoming these challenges. Staying organized through meticulous documentation and leveraging digital tools can help contract CRAs efficiently meet monitoring visit deadlines and regulatory requirements.

What are the key skills and qualifications needed to thrive as a Contract CRA (Clinical Research Associate), and why are they important?

To thrive as a Contract CRA, you need a solid understanding of clinical research protocols, regulatory guidelines (like GCP/ICH), and typically a degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, clinical trial management systems (CTMS), and sometimes certifications like ACRP or SOCRA are beneficial. Strong attention to detail, excellent organizational skills, and effective communication are crucial soft skills for managing multiple studies and collaborating with sites. These competencies are essential for ensuring compliance, data integrity, and the smooth execution of clinical trials.

What Are Contract CRA Jobs?

A contract clinical research associate (contract CRA) is a temporary position in which you manage clinical trials and scientific research projects. As a contractor, you work temporarily on a contract that typically lasts for the duration of the project. Clinical research associates work in the pharmaceutical industry to ensure the safety and effectiveness of medication or vaccines. You can also work on studies for biotech companies and projects that perform analysis on surgical procedures or treatments. Your duties focus on planning the trial, defining the parameters, ensuring the safety of participants, and making sure the project meets all regulations and requirements.

What are contract crafters?

Contract crafters are professionals who specialize in creating, reviewing, and negotiating contracts for individuals or organizations. They ensure that agreements are legally sound, clearly written, and protect the interests of all parties involved. Contract crafters may work in a variety of industries, including business, law, real estate, and technology. Their expertise helps minimize risk and ensure compliance with relevant laws and regulations.
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Contract Cra jobs near you
Infographic showing various Contract Cra job openings in the United States as of June 2026, with employment types broken down into 71% Full Time, 1% Temporary, and 28% Contract. Highlights an 80% Physical, 2% Hybrid, and 18% Remote job distribution, with an average salary of $85,542 per year, or $41.1 per hour.
Clinical Research Associate II

Clinical Research Associate II

Systimmune

Princeton, NJ • Remote

$80K - $110K/yr

Full-time

Posted 27 days ago

Job description

SystImmune is seeking a high quality, ambitious and experienced Clinical Research Associate II (CRA II) to support SystImmune’s clinical trials.   The CRA II is responsible for the management and oversight of their assigned clinical study sites to ensure data quality and patient safety in accordance with ICH-GCP guidelines, local regulations, and applicable SOPs.  The CRA II must be self-motivated, independent, and able to work in a small team environment. The successful candidate will be a highly organized individual who can also multitask and adjust direction based on changing project/corporate priorities.
Job Responsibilities:
  • Perform Site Evaluation Visits, Site Initiation Visits, Interim monitoring visits and Close Out Visits
  • Prepare the study reference manual, including liaising with the Contract Research Organization (CRO) team (i.e., central lab, specialty labs and vendors) to ensure efficient preparation and delivery of study materials to investigator sites
  • Responsible for ensuring investigator sites have met all contractual and regulatory requirements for site initiation and first release of study drug
  • Assist in the development of study/program plans (i.e., Monitoring Plan, eCRF Completion Guidelines, Data Management Plan, Safety Management Plan, etc.)
  • Manage patient recruitment strategies, proactively identifying barriers to recruitment while proposing solutions (i.e., study-site webinars, newsletters or other potential creative solutions)
  • Monitor recruitment, data quality and patient safety while on site and remotely through EDC systems and direct site communication
  • Liaise with study site personnel to ensure timely and correct entry of data into eCRF, including the timely resolution of data queries
  • Maintain project files including ethics committee approvals, curricula vitae of investigators and study personnel, clinical investigators brochure, protocols, case report forms instructions, consent documents, clinical-trial material shipping orders, start-up meeting attendance documentation, letters of agreement, lab reference ranges, and all investigator and site correspondence
  • Identify and complete follow- up of SAEs at study sites
  • Assist with data listing, data coding, patient profile reviews, database lock, and site close-out activities
  • Ensure appropriate and timely submission of documents to the Trial Master File
  • Perform investigational product (IP) inventory, reconciliation and reviews storage and security. Verifies the IP has been dispensed and administered to subjects/patients according to the protocol. Verifies issues or risks associated with blinded or randomized information related to IP. 
Qualifications: 
  • Bachelor’s degree in health science or related field.
  • 2+ years monitoring Oncology trials independently conducting on-site and remote monitoring visits.
  • Excellent verbal and written communication skills required.
  • Excellent organizational, multi-tasking and time management skills required.
  • Demonstrated experience developing/maintaining site relationships and securing compliance
  • Working knowledge of International Conference on Harmonization Good Clinical Practice guidelines
  • Experienced in Microsoft Office Products (Word, Excel, PowerPoint, SharePoint, Teams) and other clinical trial systems (e.g., CTMS, EDC and eTMF)
  • Ability to travel as required (50-75%)
Compensation and Benefits:
The expected base salary range for this position is $80,000 - $110,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.
 

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