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Clinical Research Associate 1099 Jobs (NOW HIRING)

ICON

Senior Clinical Research Associate

Blue Bell, PA · On-site

ICON plc is seeking an experienced Senior Clinical Research Associate (Senior CRA) or Clinical Research Associate (CRA) to join our dynamic, collaborative team. In this role, you will be a key ...

Icon plc

Senior Clinical Research Associate

Houston, TX · Hybrid

Contract Senior Clinical Research Associate - Home-Based (US) ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to ...

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Clinical Research Associate 1099 information

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$36K

$94.3K

$143.5K

How much do clinical research associate 1099 jobs pay per year?

As of Jul 20, 2026, the average yearly pay for clinical research associate 1099 in the United States is $94,314.00, according to ZipRecruiter salary data. Most workers in this role earn between $62,500.00 and $128,000.00 per year, depending on experience, location, and employer.

What is a Clinical Research Associate 1099?

A Clinical Research Associate (CRA) 1099 is an independent contractor who oversees clinical trials for pharmaceutical, biotechnology, or medical device companies. Unlike traditional W-2 employees, CRAs working under a 1099 agreement operate as self-employed professionals, managing their own taxes and benefits. Their responsibilities include monitoring study sites, ensuring compliance with protocols, and safeguarding patient safety and data integrity. This role offers more flexibility but also requires handling administrative tasks that would typically be managed by an employer.

What are some common challenges independent (1099) Clinical Research Associates face, and how can they be managed?

Independent Clinical Research Associates (CRAs) often face challenges such as managing multiple sponsor expectations, maintaining consistent study documentation, and navigating variable workloads. As a 1099 contractor, you are responsible for your own scheduling, invoicing, and tax obligations, which requires strong organizational skills. Building clear communication channels with sponsor teams and staying updated on regulatory requirements can help ensure study quality and compliance. Networking with other independent CRAs and utilizing professional resources can also provide support and guidance.

What are the key skills and qualifications needed to thrive as a Clinical Research Associate 1099, and why are they important?

To thrive as a Clinical Research Associate 1099, you need a solid understanding of clinical trial protocols, GCP (Good Clinical Practice) guidelines, and typically a bachelor’s degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, regulatory documentation, and often certifications like ACRP or SOCRA are important. Strong organizational skills, attention to detail, and effective communication enable you to manage multiple studies and collaborate with diverse teams. These skills ensure compliance, data integrity, and the successful execution of clinical research projects.

What is the difference between Clinical Research Associate 1099 vs Clinical Research Associate W-2?

AspectClinical Research Associate 1099Clinical Research Associate W-2
Employment StatusIndependent contractorEmployee
TaxationResponsible for own taxes, self-employedTaxes withheld by employer
Work EnvironmentTypically contract-based, flexible locationsUsually full-time, in-house or site-based
CredentialsOften similar certifications, e.g., CCR, but no employer-mandated benefitsSame certifications, with benefits provided by employer

The main difference between a Clinical Research Associate 1099 and a W-2 is employment status. The 1099 role is an independent contractor, offering flexibility but requiring self-management of taxes and benefits. The W-2 role is a traditional employee position with taxes and benefits handled by the employer. Both roles often require similar credentials and work in comparable environments, but their employment structure impacts taxes, benefits, and work arrangements.

More about Clinical Research Associate 1099 jobs
What cities are hiring for Clinical Research Associate 1099 jobs? Cities with the most Clinical Research Associate 1099 job openings:
What states have the most Clinical Research Associate 1099 jobs? States with the most job openings for Clinical Research Associate 1099 jobs include:
What job categories do people searching Clinical Research Associate 1099 jobs look for? The top searched job categories for Clinical Research Associate 1099 jobs are:
Clinical Research Associate 1099 jobs near you
Infographic showing various Clinical Research Associate 1099 job openings in the United States as of July 2026, with employment types broken down into 83% Full Time, and 17% Part Time. Highlights an 75% In-person, and 25% Remote job distribution, with an average salary of $94,314 per year, or $45.3 per hour.
Clinical Research Associate- RN or Clinical Research Associate I

Clinical Research Associate- RN or Clinical Research Associate I

St. Jude Children's Research Hospital

Memphis, TN • On-site

$65K - $114K/yr

Full-time

Posted 5 days ago

St. Jude Children's Research Hospital rating

8.4

Company rating: 8.4 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

65th of 1,020 rated hospitals

Job description

The World's Best Stop at Nothing
There's a reason St. Jude Children's Research Hospital is consistently ranked on Glassdoor's "Best Places to Work" list. Actually, there are more than 6,500 reasons. At our world-class pediatric research hospital, every one of our 6,500 professionals shares our commitment to making a difference in the lives of the children we serve. There's a unique bond when you are part of a team that will stop at nothing to advance the treatments and cures of pediatric catastrophic diseases. The result is a collaborative, positive environment where all employees, regardless of their role, receive the resources, support, and encouragement to advance and grow their careers.
At St. Jude Children's Research Hospital, the Department of Radiology plays a vital role in advancing the quality of care and improving outcomes for children facing catastrophic diseases. Our mission is grounded in delivering exceptional, specialized imaging across multiple modalities to guide both diagnosis and therapy monitoring.
We balance this clinical excellence with a deep commitment to research and innovation, continuously exploring technologies that enhance diagnostic precision and expand the boundaries of pediatric imaging. Our team is dedicated to performing at the highest levels of patient care and scientific discovery, integrating innovation into every aspect of our work.
At St. Jude, we believe that better imaging leads to better outcomes for every patient.
Job Summary
Operates under general supervision. Performs data abstraction, collection, and entry to support clinical research. Prepares submission for all reportable events. Develops, maintains, and/or monitors case report forms. Ensures compliance with prescribed interventions and evaluations of the assigned protocol(s). Provides data to the collaborating research organization or study sponsor. Prepares data reports. The Clinical Research Associate - RN also provides patient care, education, and management. Position has a dotted line reporting relationship to the Nursing Executive/CNO. Coordinates with supervisor and Nursing Executive/CNO to ensure consistent institution-wide compliance with standards of nursing practice.
Job Responsibilities:
  • Perform data abstraction, collection, and entry to support clinical research.
  • Assist with submission for all reportable events (e.g., adverse events, protocol variations).
  • Maintain/enter data as required for case report forms.
  • Ensure compliance with prescribed interventions and evaluations of the assigned protocol(s).
  • Provide data to the collaborating research organization (CRO) or study sponsor, and prepare data reports as directed.
  • (As applicable) Provide patient care, education, and management (e.g., routine test conduct; assistance in clinical procedures; medication instruction, monitoring, and documentation; patient care coordination; education on protocol activities)
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Maintains regular and predictable attendance.

Minimum Education and/or Training:
For Clinical Research Associate - RN:
  • Bachelor's degree in Nursing required.

For Clinical Research Associate I:
  • Bachelor's degree in relevant area required.

Minimum Experience:
Prior industry experience preferred.
Licensure, Registration and/or Certification Required by Law:
For Clinical Research Associate - RN:
  • (LC: RN-TN) Must possess a current Tennessee State Board of Nursing license if primary residence is Tennessee or a Nurse Licensure Non-Compact state.
  • (LC: RN-MISS, RN-ARK or RN-KY) Must possess a current State Board of Nursing license in the state of primary residence if the state is a Nurse Licensure Compact state.

For Clinical Research Associate I:
  • None

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Clinical Research Associate- RN or Clinical Research Associate I.
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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