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Clinical Research Associate 1099 Jobs (NOW HIRING)

CRA II

Blue Bell, PA · On-site

As a Clinical Research Associate at ICON, you will play a pivotal role in designing and analyzing clinical trials, interpreting complex medical data, and contributing to the advancement of innovative ...

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Clinical Research Associate 1099 information

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$36K

$94.3K

$143.5K

How much do clinical research associate 1099 jobs pay per year?

As of Sep 1, 2026, the average yearly pay for clinical research associate 1099 in the United States is $94,314.00, according to ZipRecruiter salary data. Most workers in this role earn between $62,500.00 and $128,000.00 per year, depending on experience, location, and employer.

What is a clinical research associate 1099?

A Clinical Research Associate (CRA) 1099 is an independent contractor who oversees clinical trials for pharmaceutical, biotechnology, or medical device companies. Unlike traditional W-2 employees, CRAs working under a 1099 agreement operate as self-employed professionals, managing their own taxes and benefits. Their responsibilities include monitoring study sites, ensuring compliance with protocols, and safeguarding patient safety and data integrity. This role offers more flexibility but also requires handling administrative tasks that would typically be managed by an employer.

What are the key skills and qualifications needed to thrive as a clinical research associate 1099?

To thrive as a Clinical Research Associate 1099, you need a solid understanding of clinical trial protocols, GCP (Good Clinical Practice) guidelines, and typically a bachelor’s degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, regulatory documentation, and often certifications like ACRP or SOCRA are important. Strong organizational skills, attention to detail, and effective communication enable you to manage multiple studies and collaborate with diverse teams. These skills ensure compliance, data integrity, and the successful execution of clinical research projects.

What are some common challenges independent (1099) clinical research associates face, and how can they be managed?

Independent Clinical Research Associates (CRAs) often face challenges such as managing multiple sponsor expectations, maintaining consistent study documentation, and navigating variable workloads. As a 1099 contractor, you are responsible for your own scheduling, invoicing, and tax obligations, which requires strong organizational skills. Building clear communication channels with sponsor teams and staying updated on regulatory requirements can help ensure study quality and compliance. Networking with other independent CRAs and utilizing professional resources can also provide support and guidance.

What is the difference between Clinical Research Associate 1099 vs Clinical Research Associate W-2?

AspectClinical Research Associate 1099Clinical Research Associate W-2
Employment StatusIndependent contractorEmployee
TaxationResponsible for own taxes, self-employedTaxes withheld by employer
Work EnvironmentTypically contract-based, flexible locationsUsually full-time, in-house or site-based
CredentialsOften similar certifications, e.g., CCR, but no employer-mandated benefitsSame certifications, with benefits provided by employer

The main difference between a Clinical Research Associate 1099 and a W-2 is employment status. The 1099 role is an independent contractor, offering flexibility but requiring self-management of taxes and benefits. The W-2 role is a traditional employee position with taxes and benefits handled by the employer. Both roles often require similar credentials and work in comparable environments, but their employment structure impacts taxes, benefits, and work arrangements.

More about Clinical Research Associate 1099 jobs

What cities are hiring for Clinical Research Associate 1099 jobs?

Cities with the most Clinical Research Associate 1099 job openings:

What states have the most Clinical Research Associate 1099 jobs?

States with the most job openings for Clinical Research Associate 1099 jobs include:

Infographic showing various Clinical Research Associate 1099 job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 70% Full Time, 27% Part Time, 1% Temporary, and 1% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $94,314 per year, or $45.3 per hour.

Clinical Research Associate

Blue Bell, PA

ICON Clinical Research
Biotechnology Research and Development • 201 - 500 employees

Full-time

Medical, Life, Retirement, PTO

Posted 3 days ago

New


Job description

Senior Clinical Research Associate - Oncology

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

We are currently seeking a Clinical Research Associate (CRA) to join our diverse and dynamic team. As a CRA at ICON Plc, you will play a critical role in overseeing and managing clinical trial activities to ensure they are conducted according to protocol, regulatory requirements, and industry standards. You will contribute to the success of clinical trials by ensuring data integrity, participant safety, and compliance throughout the study lifecycle.

What You Will Be Doing:

  • Monitoring clinical trial sites to ensure adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards.
  • Conducting site visits to assess site performance, resolve issues, and provide support to ensure successful trial execution.
  • Collaborating with cross-functional teams to ensure timely and accurate data collection and reporting.
  • Providing training and guidance to site staff and other CRAs to maintain high standards of clinical trial conduct.
  • Building and maintaining effective relationships with site personnel and stakeholders to facilitate smooth trial operations.

Your Profile:

  • Advanced degree in a relevant field such as life sciences, nursing, or medicine.
  • Extensive experience as a Clinical Research Associate, with a strong understanding of clinical trial processes and regulatory requirements.
  • Proven ability to manage multiple sites and projects simultaneously, with strong organizational and problem-solving skills.
  • Expertise in monitoring practices, data integrity, and site management, with proficiency in relevant clinical trial software and tools.
  • Excellent communication, interpersonal, and stakeholder management skills, with the ability to influence and drive compliance within a complex environment.
  • Ability to travel at least 60% of the time (international and domestic - fly and drive) and should possess a valid driver's license

What ICON can offer you:

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

  • Various annual leave entitlements
  • A range of health insurance offerings to suit you and your family's needs.
  • Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
  • Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.
  • Life assurance
  • Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site (https://careers.iconplc.com/benefits) to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here (https://careers.iconplc.com/reasonable-accommodations)

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless - there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here (https://wd3.myworkday.com/icon/d/task/1422$1235.htmld) to apply