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Clinical Research Associate 1099 Jobs (NOW HIRING)

Piper Companies

Clinical Research Associate

Chicago, IL · Hybrid

$120K - $135K/yr

Piper Companies is actively seeking Clinical Research Associates to join a toptier CRO with a proven track record of excellence, trusted by global pharma and biotech partners. This position is fully ...

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$36K

$94.3K

$143.5K

How much do clinical research associate 1099 jobs pay per year?

As of May 28, 2026, the average yearly pay for clinical research associate 1099 in the United States is $94,314.00, according to ZipRecruiter salary data. Most workers in this role earn between $62,500.00 and $128,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Clinical Research Associate 1099, and why are they important?

To thrive as a Clinical Research Associate 1099, you need a solid understanding of clinical trial protocols, GCP (Good Clinical Practice) guidelines, and typically a bachelor’s degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, regulatory documentation, and often certifications like ACRP or SOCRA are important. Strong organizational skills, attention to detail, and effective communication enable you to manage multiple studies and collaborate with diverse teams. These skills ensure compliance, data integrity, and the successful execution of clinical research projects.

What are some common challenges independent (1099) Clinical Research Associates face, and how can they be managed?

Independent Clinical Research Associates (CRAs) often face challenges such as managing multiple sponsor expectations, maintaining consistent study documentation, and navigating variable workloads. As a 1099 contractor, you are responsible for your own scheduling, invoicing, and tax obligations, which requires strong organizational skills. Building clear communication channels with sponsor teams and staying updated on regulatory requirements can help ensure study quality and compliance. Networking with other independent CRAs and utilizing professional resources can also provide support and guidance.

What is a Clinical Research Associate 1099?

A Clinical Research Associate (CRA) 1099 is an independent contractor who oversees clinical trials for pharmaceutical, biotechnology, or medical device companies. Unlike traditional W-2 employees, CRAs working under a 1099 agreement operate as self-employed professionals, managing their own taxes and benefits. Their responsibilities include monitoring study sites, ensuring compliance with protocols, and safeguarding patient safety and data integrity. This role offers more flexibility but also requires handling administrative tasks that would typically be managed by an employer.

What is the difference between Clinical Research Associate 1099 vs Clinical Research Associate W-2?

AspectClinical Research Associate 1099Clinical Research Associate W-2
Employment StatusIndependent contractorEmployee
TaxationResponsible for own taxes, self-employedTaxes withheld by employer
Work EnvironmentTypically contract-based, flexible locationsUsually full-time, in-house or site-based
CredentialsOften similar certifications, e.g., CCR, but no employer-mandated benefitsSame certifications, with benefits provided by employer

The main difference between a Clinical Research Associate 1099 and a W-2 is employment status. The 1099 role is an independent contractor, offering flexibility but requiring self-management of taxes and benefits. The W-2 role is a traditional employee position with taxes and benefits handled by the employer. Both roles often require similar credentials and work in comparable environments, but their employment structure impacts taxes, benefits, and work arrangements.

More about Clinical Research Associate 1099 jobs
What cities are hiring for Clinical Research Associate 1099 jobs? Cities with the most Clinical Research Associate 1099 job openings:
What states have the most Clinical Research Associate 1099 jobs? States with the most job openings for Clinical Research Associate 1099 jobs include:
What job categories do people searching Clinical Research Associate 1099 jobs look for? The top searched job categories for Clinical Research Associate 1099 jobs are:
Clinical Research Associate 1099 jobs near you
Clinical Research Assoc III

Clinical Research Assoc III

Tranquil Clinical Research

Webster, TX

Other

Posted 26 days ago

Job description

Clinical Research Associate III

The Clinical Research Associate III will play a pivotal role in the management and oversight of clinical trials, ensuring that they are conducted in compliance with regulatory requirements and company standards. This position is responsible for monitoring study sites, collecting and analyzing data, and ensuring the integrity of the research process. The successful candidate will collaborate with cross-functional teams to facilitate the smooth execution of clinical studies, contributing to the advancement of medical knowledge and patient care. Additionally, the Clinical Research Associate III will provide training and mentorship to junior staff, fostering a culture of excellence and continuous improvement. Ultimately, this role is essential in driving the success of clinical research initiatives that can lead to innovative healthcare solutions.

Minimum Qualifications:

  • Bachelor's degree in life sciences, nursing, or a related field.
  • At least 3 years of experience in clinical research monitoring.
  • Must have oncology experience
  • Strong understanding of Good Clinical Practice (GCP) and regulatory requirements.
  • Trip report review experience
  • PSSV, SIV, IMV, COV and TMF reconciliation experience
  • Onsite monitoring experience with at least 3 years

Preferred Qualifications:

  • Master's degree in a relevant field.
  • Experience with electronic data capture (EDC) systems.
  • Certification as a Clinical Research Associate (CRA) or Clinical Research Coordinator (CRC).

Responsibilities:

  • Monitor clinical trial sites to ensure compliance with study protocols and regulatory requirements.
  • Conduct site visits, perform source document verification, and ensure data integrity.
  • Collaborate with investigators and site staff to facilitate the smooth execution of clinical studies.
  • Prepare and review study-related documentation, including protocols, informed consent forms, and reports.
  • Provide training and support to junior clinical research associates and other team members.

The required skills for this position include strong analytical abilities, which are essential for evaluating clinical data and ensuring compliance with protocols. Excellent communication skills are necessary for effectively collaborating with site staff and presenting findings to stakeholders. Attention to detail is critical in monitoring clinical trials and verifying data accuracy. Preferred skills, such as proficiency in EDC systems, enhance the efficiency of data collection and management processes. Overall, a combination of these skills will enable the Clinical Research Associate III to contribute significantly to the success of clinical research projects.

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