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Clinical Trial Manager Jobs (NOW HIRING)

Frontier Medicines

Clinical Trial Manager

Boston, MA · Hybrid

$120K - $150K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Frontier Medicines is seeking two Clinical Trial Managers to support the day-to-day execution of our oncology clinical trials as they advance through clinical development. Working under the guidance ...

Ocugen Inc

Clinical Trial Manager

Malvern, PA · On-site

Position Summary The Clinical Trial Manager (CTM) is responsible for the overall operational management and execution of clinical trials from initiation through close-out. This includes leading the ...

OCUGEN OPCO INC

Clinical Trial Manager

Malvern, PA · On-site

Position Summary The Clinical Trial Manager (CTM) is responsible for the overall operational management and execution of clinical trials from initiation through close-out. This includes leading the ...

Frontier Medicines

Clinical Trial Manager

Boston, MA · On-site

$120K - $150K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Frontier Medicines is seeking two Clinical Trial Managers to support the day-to-day execution of our oncology clinical trials as they advance through clinical development. Working under the guidance ...

Sagimet Biosciences

Clinical Trial Manager

San Mateo, CA · On-site

$90 - $100/hr

Job Type Contract Description The Clinical Trial Manager manages and leads the day-to-day clinical trial activities related to the development and execution of cross-functional and third-party vendor ...

Frontier Medicines

Clinical Trial Manager

Boston, MA · On-site

$120K - $150K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Frontier Medicines is seeking two Clinical Trial Managers to support the day-to-day execution of our oncology clinical trials as they advance through clinical development. Working under the guidance ...

PROMETRIKA, LLC

Clinical Trial Manager

Cambridge, MA · On-site

Clinical Trial Manager PROMETRIKA is a full-service clinical research organization (CRO) with extensive experience in clinical operations, data management, biostatistics, medical writing, and ...

Verastem

Clinical Trial Manager

Boston, MA · On-site

$100K - $125K/yr

We are seeking a Clinical Trial Manager with experience in managing a global Phase 3 clinical trial. Works with senior Clinical Operations members to lead the clinical project team members in the ...

Collabera

Clinical Trial Manager

Jersey City, NJ

Knowledge and experience in clinical study budgeting including timeline and the application of clinical trial performance metrics. Demonstrated ability to support the development and management of ...

Aerogen Ltd

Clinical Trial Manager

Morrisville, NC · On-site

  • Life

The Clinical Trial Manager (CTM) is responsible for managing various aspects of clinical trials including study start-up, site management and monitoring activities. This includes vendor management ...

Clinovo

Clinical Trial Manager

Cambridge, MA · On-site

$175K/yr

The Clinical Trial Manager (CTM) plays a key role in the successful execution of clinical research studies, providing operational leadership from study initiation through final closeout. This ...

Kymera Therapeutics

Clinical Trial Manager

Watertown, MA · On-site

$115K - $200K/yr

Responsible for management of vendors to support clinical trial execution * Plan, execute, and lead study-specific meetings (e.g., internal core team meetings, investigator meetings, etc), as needed

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How much do clinical trial manager jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for clinical trial manager in the United States is $62.52, according to ZipRecruiter salary data. Most workers in this role earn between $50.72 and $70.43 per hour, depending on experience, location, and employer.

What does a clinical trial manager do?

A clinical trial manager, or CTM, oversees research and each phase of clinical drug tests at a hospital. They work closely with both the doctors and clinicians who are performing the trial, as well as the sponsor of the study, which is typically a pharmaceutical company or other health care organization. As a CTM, duties and responsibilities include planning and managing the trial, making sure that the test meets all government standards, and determining if it was successful. Clinical trial managers also hire, train, and evaluate the members of the clinical team.

What are the key skills and qualifications needed to thrive as a clinical trial manager, and why are they important?

To thrive as a Clinical Trial Manager, you need a solid background in life sciences, clinical research experience, and often a relevant bachelor's or master's degree. Familiarity with clinical trial management systems (CTMS), regulatory requirements like GCP, and certifications such as ACRP or SOCRA are highly beneficial. Strong organizational skills, attention to detail, leadership, and effective communication are critical soft skills for managing teams and stakeholders. These skills ensure trials are conducted ethically, efficiently, and compliantly, leading to successful study outcomes.

What does a clinical trial manager do?

A Clinical Trial Manager oversees the planning, coordination, and execution of clinical trials for new drugs, medical devices, or treatments. They ensure that trials are conducted in compliance with regulatory guidelines, company protocols, and ethical standards. Their responsibilities include managing budgets, timelines, and teams, as well as monitoring data quality and safety throughout the study. Clinical Trial Managers also work closely with investigators, sponsors, and regulatory agencies to ensure successful trial outcomes.

What are some common challenges clinical trial managers face when coordinating multi-site studies?

Clinical Trial Managers often encounter challenges such as ensuring consistent protocol implementation across different sites, managing timelines in the face of site-specific delays, and maintaining clear communication among diverse teams. They must also navigate regulatory differences between regions and address unforeseen issues like patient recruitment shortfalls or data discrepancies. Success in this role requires strong organizational skills, adaptability, and proactive problem-solving to keep studies on track and compliant.
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Clinical Trial Manager jobs near you
Infographic showing various Clinical Trial Manager job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 12% Part Time, and 1% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $130,034 per year, or $62.5 per hour.

Clinical Trial Manager/Senior Clinical Trial Manager

Janux Therapeutics

San Diego, CA • On-site

$140K - $178K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 6 days ago

Job description

The Senior/Clinical Trial Manager will be responsible for managing and executing operational aspects of assigned clinical trials, from study start-up to close-out, with a focus on autoimmune studies. This individual will be instrumental in managing and overseeing CROs, study vendors, and clinical trial sites, while partnering with key internal stakeholders to ensure clinical trial deliverables are completed on time, within budget, and in accordance with regulatory requirements, GCP guidelines, and internal SOPs. This position reports directly to the Senior Director of Clinical Operations and serves as an integral member of the Clinical Operations team, contributing to the development of trial strategy, executing initiatives, and ensuring the highest standards in operational delivery. This is a great opportunity to make a meaningful impact in a fast-paced, mission-driven biotech environment.
ESSENTIAL FUNCTIONS AND RESPONSIBILITIES
  • Support the successful execution of clinical trials from protocol concept to clinical study report in support of complex autoimmune programs.
  • Prepare and maintain study-related files and documentation to ensure inspection readiness.
  • Organize and lead study and departmental meetings, including minute-taking and document archiving.
  • Coordinate clinical trial equipment, supplies, and cross-functional project activities (e.g., Clinical Data Review Meetings).
  • Ensure team compliance with study-specific training and perform TMF reviews for completeness.
  • Support clinical sites in preparation for audits and inspections.
  • Assist with budget management and day-to-day clinical operations in compliance with SOPs, ICH/GCP, and regulatory requirements.
  • Track subject and site activity/metrics and perform quality checks across study components.
  • Proactively identify and escalate issues related to functional deliverables.
  • Contribute to study set-up activities including protocol/synopsis development, informed consent forms, system configuration (CTMS, IRT), regulatory submissions, and operational documentation.
  • Collaborate with CROs to ensure timely collection and archiving of TMF documents.
  • Coordinate with regulatory affairs on essential document submissions.
  • Support study close-out activities including TMF and drug reconciliation and CSR readiness.
  • Communicate effectively with study team members and work closely with Clinical Trial Managers and/or Asset Leads.
  • Participate in process improvement and quality initiatives related to study execution.
  • Other duties as deemed necessary.

REQUIRED EDUCATION, EXPERIENCE, SKILLS, AND ABILITIES
  • Bachelor's degree with at least 5 years (CTM) or 8 years (Sr. CTM) of hands-on clinical trial experience, preferably within a pharmaceutical or biotech environment. A combination of CRO and sponsor-side experience will be considered.
  • Demonstrated experience in complex autoimmune clinical trials, including trial set-up, monitoring, and close-out.
  • Strong working knowledge of ICH/GCP regulations.
  • Proficiency with electronic systems such as eTMF, CTMS, EDC, etc.
  • Ability to work independently with minimal oversight and thrive in a collaborative team environment.
  • Strong critical thinking skills, a sense of urgency, and a proactive problem-solving mindset.
  • Excellent interpersonal, written, and verbal communication skills.
  • Proficiency in MS Office and comfort with technology.
  • Minimal travel required (0 to 5%).

$140,000 - $178,000 a year
In addition to a competitive base salary ranging from $140,000 to $154,000 for Clinical Trial Manager and $160,000 to $178,000, we offer stock options, restricted stock units, a stock purchase plan (ESPP) and a target bonus. Janux also provides a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, and supplemental disability insurance. Relocation assistance may also be available.
Please note that the hourly rate range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, and internal equity.
Job Type:Full-time
Benefits:
  • Annual bonus program
  • Incentive stock option plan
  • 401k plan with flat non-elective employer contribution
  • Comprehensive medical insurance with 90-100% employer-paid premiums
  • Dental and vision insurance
  • HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity)
  • Unlimited PTO
  • Generous holiday schedule; includes summer and winter company shutdown
  • Relocation assistance

Schedule:
  • Monday to Friday

Work authorization:
  • United States (Required)

Additional Compensation:
  • Annual targeted bonus %

Work Location:
  • Hybrid preferred in San Diego office. Remote permitted upon approval, with ability to travel 25% for meetings or site visits as required.

EQUAL OPPORTUNITY EMPLOYER:
Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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