What are some common challenges Python Django web developers face when working on large-scale projects?

Python Django Web Developers working on large-scale projects often encounter challenges such as maintaining performance as the application grows, ensuring code scalability, and managing complex database relationships. Collaborating effectively with front-end developers and DevOps teams to streamline deployment and continuous integration is also crucial. Additionally, keeping up with security best practices and incorporating robust testing can be demanding but is essential for delivering reliable web applications.