What is histocompatibility?
Career: Histocompatibility
Histocompatibility refers to the compatibility between the tissues of different individuals, primarily in the context of organ or tissue transplantation. It is determined by specific proteins on cell surfaces, known as human leukocyte antigens (HLA), which help the immune system recognize which cells belong in the body. Matching these antigens as closely as possible between donor and recipient reduces the risk of transplant rejection. Histocompatibility testing is therefore crucial in selecting suitable donors for procedures like kidney, bone marrow, or heart transplants.
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