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Weekend Rn Jobs in Columbia, SC (NOW HIRING)

NHC

WEEKEND RN SUPERVISOR-7A-7P

West Columbia, SC · On-site

Weekend Registered Nurse Are you looking to make a difference in the lives of others by sharing your care and compassion? Do you enjoy connecting with your patients while getting to know them and ...

Franke

Hospice Weekend On Call RN

Chapin, SC · On-site

The Weekend On Call RN is responsible for delivering compassionate, high-quality nursing care to hospice patients and their families during weekend hours. This role ensures continuity of care from ...

Franke at Seaside

Hospice Weekend On Call RN

Chapin, SC · On-site

The Weekend On Call RN is responsible for delivering compassionate, high-quality nursing care to hospice patients and their families during weekend hours. This role ensures continuity of care from ...

TNAA TotalMed RN

Travel OR RN

Camden, SC · On-site

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Camden, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Start Date:

TNAA TotalMed RN

Travel OR RN

Columbia, SC · On-site

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration: 13 ...

TNAA TotalMed RN

Travel OR RN

Camden, SC · On-site

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Camden, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration: 13 ...

TNAA TotalMed RN

Travel OR RN

Columbia, SC · On-site

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration: 13 ...

TNAA TotalMed RN

Travel OR RN

Camden, SC · On-site

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Camden, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration: 13 ...

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All JobsRn JobsWeekend Rn JobsWeekend Rn Jobs in Columbia, SC

Weekend Rn information

See Columbia, SC salary details

$25

$39

$66

How much do weekend rn jobs pay per hour?

As of Aug 20, 2026, the average hourly pay for weekend rn in Columbia, SC is $39.83, according to ZipRecruiter salary data. Most workers in this role earn between $31.61 and $45.98 per hour, depending on experience, location, and employer.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

More about Weekend Rn jobs

What are the most commonly searched types of Rn jobs in Columbia, SC?

The most popular types of Rn jobs in Columbia, SC are:

What are popular job titles related to Weekend Rn jobs in Columbia, SC?

For Weekend Rn jobs in Columbia, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Rn jobs in Columbia, SC look for?

The top searched job categories for Weekend Rn jobs in Columbia, SC are:

What cities near Columbia, SC are hiring for Weekend Rn jobs?

Cities near Columbia, SC with the most Weekend Rn job openings:

Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in Columbia, SC as of August 2026, with employment types broken down into 74% Full Time, 23% Part Time, and 3% Contract. Highlights an 100% In-person job distribution, with an average salary of $82,856 per year, or $39.8 per hour.

Weekend Registered Nurse RN

Springdale Healthcare Center

Camden, SC

$35 - $37/hr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 9 days ago

Job description

Premium added to base wage for Weekend Diamond Program Nurse.  

Must work Friday/Saturday/Sunday or Saturday/Sunday/Monday 7a-7p or 7p-7a


Working in harmony with the entire nursing staff, the Registered Nurse RN strives to provide the very best care possible. If you are a Registered Nurse RN with a true passion for patient care and compassion for others, with a commitment to teamwork, apply today!


USD $35.00 - USD $37.00 /Hr.
The wage range for this role takes into account the wide range of factors that are considered in making compensation decisions including, but not limited to, skill sets, experience, education and training, licensure and certifications, and other business and organizational needs.

  • Work under direct supervision using the state-specific Nurse Practice Act, Practice Guidelines and nursing judgment
  • Deliver nursing care to patients requiring care, collecting patient data, making observations and reporting pertinent information to the care of patients
  • Direct and supervise care given by other nursing staff members as needed

  • Must be a licensed RN in good standing with the state (as required)
  • 1+ years of nursing experience in a long-term care facility strongly preferred
  • Reliable transportation required

All of our employees are valued and receive a competitive wage; full time team members are also offered a comprehensive benefit package which includes: 

  • Medical, Dental, Vision, Life and Disability Insurance/ Flexible Spending Accounts
  • Tuition Reimbursement & Nursing Loan Repayment Programs
  • PerkSpot - Local Deals and Weekly Perks Program
  • 401(k)
  • Paid Time Off Plan
  • New Pet Insurance Discount available
  • DailyPay option available! – Get your pay, when you need it.
  • Purchasing Power - online purchase/payroll deduction
  • Tickets at Work - entertainment ticket discounts
  • Employee Assistance Plan - easy-to-use services to help with everyday challenges of life (available for all employees and their families) 
  • Helping Friends Foundation - our employees’ hardship/crisis fund
  • Auto and Home Insurance - employee discount available – payroll deduction!
  • In-facility education programs and more!

Drug Free, Smoke-Free work place. Equal Opportunity Employer, including disability/vets

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