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Weekend Rn Jobs in Columbia, SC (NOW HIRING)

Nuclear Care Partners

Registered Nurse RN

Columbia, SC · On-site

Registered Nurse (RN) | Columbia, SC At Nuclear Care Partners, we provide in-home nursing care to ... Rotating Weekends Benefits * Paid Time Off (PTO) (Full-time and Part-time only) * Medical, Dental ...

Nuclear Care Partners

Registered Nurse RN

Eastover, SC · On-site

Registered Nurse (RN) | [Columbia, SC] Overview At Nuclear Care Partners, we provide in-home ... Rotating Weekends Benefits * Paid Time Off (PTO) (Full-time and Part-time only) * Medical, Dental ...

Nuclear Care Partners

Registered Nurse RN

Eastover, SC · On-site

Registered Nurse (RN) | [Columbia, SC] Overview At Nuclear Care Partners, we provide in-home ... Rotating Weekends Benefits * Paid Time Off (PTO) (Full-time and Part-time only) * Medical, Dental ...

Ironside Human Resources

Registered Nurse

Sumter, SC · On-site

$31/hr

Stackable shift differentials: nights (+$6.00), weekends (+$4.00) * Sign-on bonus available * Relocation assistance available Registered Nurse Opportunity: * Registered Nurse seeks to provide quality ...

Ironside Human Resources

Registered Nurse

Sumter, SC

$31 - $45/hr

Stackable shift differentials: nights (+$6.00), weekends (+$4.00) * Sign-on bonus available * Relocation assistance available Registered Nurse Opportunity: * Registered Nurse seeks to provide quality ...

Ironside HR

Registered Nurse

Sumter, SC · On-site

$31/hr

Stackable shift differentials: nights (+$6.00), weekends (+$4.00) * Sign-on bonus available * Relocation assistance available Registered Nurse Opportunity: * Registered Nurse seeks to provide quality ...

UHS

Registered Nurse RN Adolescents

West Columbia, SC · On-site

Responsibilities Day Shift RN 7am - 7:30pm Adolescent Inpatient Program This position will float as ... Weekday 2nd shift $6.25 & Weekend 2nd shift $9.00 Weekday 3rd shift $7.00 & Weekend 3rd shift $10 ...

UHS

Registered Nurse RN Adolescents

West Columbia, SC · On-site

Responsibilities Day Shift RN 7am - 7:30pm Adolescent Inpatient Program This position will float as ... Weekday 2nd shift $6.25 & Weekend 2nd shift $9.00 Weekday 3rd shift $7.00 & Weekend 3rd shift $10 ...

Saratoga Medical Center

Registered Nurse

Columbia, SC · On-site

GPH - Night Shift (6:00 PM-7:00 AM) (Med-Surg required; rotates to Infirmary) Schedule: 12-hour shifts | 3 shifts/week | Every other weekend Requirements * Licensure as a Registered Nurse by the ...

Saratoga Medical

Registered Nurse

Columbia, SC · On-site

GPH - Night Shift (6:00 PM-7:00 AM) (Med-Surg required; rotates to Infirmary) Schedule: 12-hour shifts | 3 shifts/week | Every other weekend Requirements * Licensure as a Registered Nurse by the ...

Saratoga Ascend

Registered Nurse

Columbia, SC · On-site

... other weekend General Nature of Work: Provides direct nursing care, patient education and ... Registered Nurses in this role may serve as a Charge Nurse on a rotating basis or as a Nurse ...

Ironside Human Resources

Registered Nurse

Sumter, SC · On-site

$31/hr

Stackable shift differentials: nights (+$6.00), weekends (+$4.00) \n * Sign\-on bonus available \n * Relocation assistance available \n Registered Nurse Opportunity: \n \n * Registered Nurse seeks to ...

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All JobsRn JobsWeekend Rn JobsWeekend Rn Jobs in Columbia, SC

Weekend Rn information

See Columbia, SC salary details

$25

$39

$66

How much do weekend rn jobs pay per hour?

As of Aug 20, 2026, the average hourly pay for weekend rn in Columbia, SC is $39.83, according to ZipRecruiter salary data. Most workers in this role earn between $31.61 and $45.98 per hour, depending on experience, location, and employer.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

More about Weekend Rn jobs

What are the most commonly searched types of Rn jobs in Columbia, SC?

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For Weekend Rn jobs in Columbia, SC, the most frequently searched job titles are:

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The top searched job categories for Weekend Rn jobs in Columbia, SC are:

What cities near Columbia, SC are hiring for Weekend Rn jobs?

Cities near Columbia, SC with the most Weekend Rn job openings:

Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in Columbia, SC as of August 2026, with employment types broken down into 74% Full Time, 23% Part Time, and 3% Contract. Highlights an 100% In-person job distribution, with an average salary of $82,856 per year, or $39.8 per hour.

Registered Nurse RN Weekend On Call Hospice

PruittHealth

Columbia, SC • On-site

Full-time

Medical, Retirement, PTO

Posted 17 days ago

PruittHealth rating

6.1

Company rating: 6.1 out of 10

Based on 132 frontline employees who took The Breakroom Quiz

117th of 242 rated social care providers

Job description

REGISTERED NURSE (RN) CASE MANAGER - HOSPICE SERVICES - WEEKEND ON CALL (Friday 4:30 PM - Monday 8:30 AM)

Join the PruittHealth Hospice family, where the health and safety of our workforce is our top priority! We're not only committed to your career, we're committed to the health and safety of all our patients and nurses. If you’re looking to be a part of a uniquely specialized team of caregivers providing hospice care in the patient’s home or care facility, then now is the time to join one of the leading providers of post-acute care.

PruittHealth Hospice will help you conquer your career goals. At PruittHealth, we are searching for caregivers who are committed to serving our patients with care and compassion, and in return, we are committed to supporting your nursing career through top-of-market pay, flexible schedules, comprehensive health plans, and more.

Investing in Our Employee-Partners with Benefits

  • Top-of-market pay
  • Annual merit increases
  • Paid time off
  • Employee Referral Bonus Program
  • Preceptorship Program and hands-on training
  • Competitive mileage reimbursement rates
  • Comprehensive health plans
  • 401(k) and profit-sharing plans

Responsibilities

  • Complete evaluations, assessments, and treatments in accordance with policy and the individualized care plan
  • Complete all documentation and records in a timely and accurate manner
  • Follow established policies and procedures as related to the scope of practice
  • Maintain continuity of patient care in a hospice setting

To apply please email Britany.Kerr@pruitthealth.com


LICENSURE, CERTIFICATION, AND EDUCATIONAL REQUIREMENTS

  • Current, active, and unrestricted Registered Nurse (RN) licensure in the state of practice

Family Makes Us Stronger. Our family, your family, one family. Committed to loving, giving, and caring. United in making a difference.

We are eager to connect with you! Apply Now to get started at PruittHealth Hospice!

As an Equal Employment Opportunity employer, all qualified applicants will receive consideration without regard to race, color, religion, sex, national origin, disability, or veteran status.

For Florida Job Postings Only:

For more information regarding Florida’s Care Provider Background Screening Clearinghouse Education and Awareness, please visit https://info.flclearinghouse.com

What PruittHealth employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About PruittHealth

Sourced by ZipRecruiter

PruittHealth will help you conquer your career goals. At PruittHealth, we are searching for nurses who are committed to serving our residents with care and compassion, and in return, we are committed to supporting your nursing career through annual merit increases, career growth programs, preceptorship, and more.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Norcross, GA, US

Year founded

1969

Social media

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