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Weekend Rn Jobs in Charleston, SC (NOW HIRING)

RN Hiring Event

North Charleston, SC

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Hospice Weekend RN On Call - Weekends - $7,500 Sign on Bonus Heartland Hospice invites you to our Open House to learn more about our current hospice openings and explore career opportunities in ...

RN Hiring Event

North Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Hospice Weekend RN On Call - Weekends - $7,500 Sign on Bonus Heartland Hospice invites you to our Open House to learn more about our current hospice openings and explore career opportunities in ...

RN Hiring Event

North Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Hospice Weekend RN On Call - Weekends - $7,500 Sign on Bonus Heartland Hospice invites you to our Open House to learn more about our current hospice openings and explore career opportunities in ...

RN Hiring Event

North Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Hospice Weekend RN On Call - Weekends - $7,500 Sign on Bonus Heartland Hospice invites you to our Open House to learn more about our current hospice openings and explore career opportunities in ...

RN Hiring Event

North Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Hospice Weekend RN On Call - Weekends - $7,500 Sign on Bonus Heartland Hospice invites you to our Open House to learn more about our current hospice openings and explore career opportunities in ...

RN Hiring Event

North Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Hospice Weekend RN On Call - Weekends - $7,500 Sign on Bonus Heartland Hospice invites you to our Open House to learn more about our current hospice openings and explore career opportunities in ...

Travel Nurse RN - CVICU

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

CVICU * Discipline: RN * Duration: 6 weeks * 48 hours per week * Shift: 12 hours, nights ... Meditech Scheduling requirements: 3 - 12 hour shifts per week to include every other weekend ...

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration ...

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration ...

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration ...

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Start Date:

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration ...

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration ...

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration ...

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration ...

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

TNAA TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration ...

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Showing results 1-20

Weekend Rn information

See Charleston, SC salary details

$25

$40

$68

How much do weekend rn jobs pay per hour?

As of Aug 20, 2026, the average hourly pay for weekend rn in Charleston, SC is $40.73, according to ZipRecruiter salary data. Most workers in this role earn between $32.32 and $47.02 per hour, depending on experience, location, and employer.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What are the most commonly searched types of Rn jobs in Charleston, SC?

The most popular types of Rn jobs in Charleston, SC are:

What are popular job titles related to Weekend Rn jobs in Charleston, SC?

For Weekend Rn jobs in Charleston, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Rn jobs in Charleston, SC look for?

The top searched job categories for Weekend Rn jobs in Charleston, SC are:

What cities near Charleston, SC are hiring for Weekend Rn jobs?

Cities near Charleston, SC with the most Weekend Rn job openings:

Infographic showing various Weekend Rn job openings in Charleston, SC as of August 2026, with employment types broken down into 2% As Needed, 63% Full Time, 24% Part Time, 2% Temporary, and 9% Contract. Highlights an 98% In-person, and 2% Remote job distribution, with an average salary of $84,721 per year, or $40.7 per hour.

RN Hiring Event

Gentiva

North Charleston, SC

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 12 days ago


Gentiva Health Services rating

7.2

Company rating: 7.2 out of 10

Based on 142 frontline employees who took The Breakroom Quiz

22nd of 242 rated social care providers


Job description

Meet the Team. Explore Careers. Discover Your Next Role in Hospice Care.

Hospice Weekend RN On Call - Weekends - $7,500 Sign on Bonus

Heartland Hospice invites you to our Open House to learn more about our current hospice openings and explore career opportunities in compassionate, patient-centered care. We are seeking passionate, committed professionals who want to make a difference in the lives of patients and families in our community.

Open House Details
Location: Heartland, North Charleston, 7410 Northside Drive, Suite 250, North Charleston, SC 26420
Date: Thursday, August 20th  
Time: 3pm - 6pm(stop by anytime between 3pm and 6pm)

What You’ll Gain by Attending

  • Meet the Heartland Hospice team and learn about our culture, mission, and values.

  • Speak directly with hiring managers and team members about open positions for RNs

  • Participate in on-site interviews and discuss potential career paths.

  • Learn how to make a meaningful impact on patients and families in hospice care.

  • Enjoy light refreshments while networking with industry professionals.


Who We’re Looking For

  • Registered Nurses (RN) licensed in the state of employment.

  • Professionals committed to providing patient-focused care and building strong relationships with patients, families, and referral sources.


Benefits for All Associates (Full-Time, Part-Time & Per Diem):

  • Competitive Pay
  • 401(k) with Company Match
  • Career Advancement Opportunities
  • National & Local Recognition Programs
  • Teammate Assistance Fund

 

Additional Full-Time Benefits:

  • Medical, Dental, Vision Insurance
  • Mileage Reimbursement or Fleet Vehicle Program
  • Generous Paid Time Off + 7 Paid Holidays
  • Wellness Programs (Telemedicine, Diabetes Management, Joint & Spine Concierge Care)
  • Education Support & Tuition Assistance (ASN to BSN, BSN to MSN)
  • Free Continuing Education Units (CEUs)
  • Company-paid Life & Long-Term Disability Insurance
  • Voluntary Benefits (Pet, Critical Illness, Accident, LTC)

Apply Today
Stop by our Open House to meet the team, interview on the spot, and explore a meaningful career in hospice care.


  • This is a safety-sensitive position
  • Employee must meet minimum requirements to be eligible for benefits
  • Where applicable, employee must meet state specific requirements
  • We are proud to be an EEO employer
  • We maintain a drug-free workplace

Heartland Hospice

At Heartland Hospice, part of Gentiva, it is our privilege to offer compassionate care in the comfort of wherever our patients call home. We are a national leader in hospice care, palliative care, home health care, and advanced illness management, with nearly 600 locations and thousands of dedicated clinicians across 38 states.

Our place is by the side of those who need us – from helping people recover from illness, injury, or surgery in the comfort of their homes to guiding patients and their families through the physical, emotional, and spiritual effects of a serious illness or terminal diagnosis.

Our nationwide reach is powered by a family of trusted brands that include:

  • Hospice care: Gentiva Hospice, Emerald Coast Hospice Care, Heartland Hospice, Hospice Plus, New Century Hospice, Regency SouthernCare, SouthernCare Hospice Services, SouthernCare New Beacon
  • Palliative care: Empatia Palliative Care, Emerald Coast Palliative Care
  • Home health care: Heartland Home Health
  • Advanced illness management: Illumia Health

With corporate headquarters in Atlanta, Georgia, and providers delivering care across the U.S., we are proud to offer rewarding careers in a collaborative environment where inspiring achievements are recognized – and kindness is celebrated.


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