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Weekend Rn Jobs in Charleston, SC (NOW HIRING)

UHS

Registered Nurse (RN)

North Charleston, SC

RNs will be scheduled 7 shifts in a two week period with alternating weekend days. Day Shift: 7:00am to 7:30pm Night Shift: 7:00pm to 7:30am Benefits include: • Tuition Assistance • Career ...

UHS

Registered Nurse (RN)

North Charleston, SC · On-site

RNs will be scheduled 7 shifts in a two week period with alternating weekend days. Day Shift: 7:00am to 7:30pm Night Shift: 7:00pm to 7:30am Benefits include: • Tuition Assistance • Career ...

GHR Healthcare

Travel Nurse RN - Dialysis

Charleston, SC

$1.64K - $1.73K/wk

Discipline: RN * Start Date: ASAP * Duration: 13 weeks * 36 hours per week * Shift: 12 hours ... Willingness to work every other weekend and participate in on-call rotation * Flu vaccine required ...

Cynet Health

RN - MS

Charleston, SC · On-site

Registered Nurse Job Title: Registered Nurse Profession: Nursing Specialty: Medical Surgical ... There is a holiday rotation, and weekend work is required every other weekend. Staffing ratios may ...

MUSC

RN

Charleston, SC

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

MUSC

RN

Charleston, SC

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

MUSC

RN

Charleston, SC

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

MUSC

RN

Charleston, SC

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

MUSC

RN

Charleston, SC

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

MUSC

RN

Charleston, SC

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

MUSC

RN

Charleston, SC

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

MUSC

RN

Charleston, SC

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

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Weekend Rn information

See Charleston, SC salary details

$25

$40

$68

How much do weekend rn jobs pay per hour?

As of May 29, 2026, the average hourly pay for weekend rn in Charleston, SC is $40.73, according to ZipRecruiter salary data. Most workers in this role earn between $32.32 and $47.02 per hour, depending on experience, location, and employer.

What Does a Weekend RN Do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

How to make an extra $1000 a month as a nurse?

Weekend RNs can increase their income by taking on additional shifts, working overtime, or picking up per diem assignments. Gaining specialized certifications, such as in IV therapy or wound care, can also qualify you for higher-paying roles or agency work, helping you reach your income goal more quickly.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

More about Weekend Rn jobs
What are the most commonly searched types of Rn jobs in Charleston, SC? The most popular types of Rn jobs in Charleston, SC are:
What are popular job titles related to Weekend Rn jobs in Charleston, SC? For Weekend Rn jobs in Charleston, SC, the most frequently searched job titles are:
What job categories do people searching Weekend Rn jobs in Charleston, SC look for? The top searched job categories for Weekend Rn jobs in Charleston, SC are:
What cities near Charleston, SC are hiring for Weekend Rn jobs? Cities near Charleston, SC with the most Weekend Rn job openings:
Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in Charleston, SC as of May 2026, with employment types broken down into 3% As Needed, 56% Full Time, 36% Part Time, and 5% Contract. Highlights an 97% In-person, and 3% Remote job distribution, with an average salary of $84,721 per year, or $40.7 per hour.

Registered Nurse (RN)

NHC HomeCare - Low Country

North Charleston, SC

Other

Posted 12 hours ago

Job description


Definition:

The Registered Nurse (RN) utilizes the nursing process in accordance with physician's orders to provide patient/family care and support/advocacy in the home setting.

Line of Authority:

Director of Nursing, Administrator/Director of Services; Regional Administrator; Assistant Vice President, HomeCare

Qualifications:
  1. Licensed Registered Nurse in the state where HomeCare agency is located.
  2. Minimum one (1) year experience as a RN/professional nurse.
  3. Experience in home care is desirable.
Performance Requirements:
  1. Ability to read, write, learn, absorb, and apply professional training; follow physician's orders and keep records in prescribed manner.
  2. Ability to be reaching, bending, squatting and twisting numerous times daily.
  3. Ability to lift 70-80 pounds on occasional basis.
  4. Ability to see and hear adequately in order to respond to auditory and visual requests from patients.
  5. Ability to speak in clear, concise voice in order to communicate adequately.
  6. Ability to carry out fine motor skills with manual dexterity.
  7. Mental acuity high enough to adequately perform job requirements.
  8. Must have reliable personal transportation and be able to drive in inclement weather and variable road conditions.
Specific Responsibilities:
  1. Utilizes the nursing process to identify and achieve patient goals: assessment, planning, implementation, and evaluation.
  2. Assesses the physical, psychosocial, and environmental factors that affect a patient's health to develop a comprehensive nursing care plan which will attain the patients desired health outcomes in a culturally comfortable way.
  3. Collaborates with the interdisciplinary team to assure personal care, medical care and rehabilitation provide for optimal patient health and well-being.
  4. Teaches patient/caregiver in various aspects of health care and disease management appropriate to needs/level of education and understanding and documents continuing needs and levels of patients/caregivers understanding.
  5. Provides and documents skilled nursing care according to the plan of care/physicians orders, policies/procedures and standards of care.
  6. Provides nursing services within the scope of practice authorized by the license issued by the state for a registered nurse.
  7. Employs strategies to promote health and a safe environment, including implementation of infection control and safety policies.
  8. Evaluates progress toward the attainment of outcomes/goals and modification of plan as needed.
  9. Participates in on-going care coordination and maintains positive relationships with referral sources, physicians/other clinicians, patients/families, and other partners.
  10. Participates with other nurses in taking weekend, night and holiday calls on a rotating basis.
  11. Continually strives to improve nursing care through participation in inservice activities, staff development activities and continuing learning.
  12. Teaches, supports, and supervises Licensed Practical Nurses and Home Health Aides.
  13. Serves on committees as assigned.
  14. Performs other duties as assigned by the DON/Administrator/Director of Services.

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