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Weekend Rn Jobs in Florence, SC (NOW HIRING)

TotalMed RN

Travel Step Down RN

Florence, SC · On-site

TotalMed RN is seeking a travel nurse RN Stepdown for a travel nursing job in Florence, South Carolina. & Requirements * Specialty: Stepdown * Discipline: RN * Duration: 13 weeks * 36 hours per week

Saratoga Ascend

Registered Nurse

Turbeville, SC · On-site

Registered Nurse Opportunities Saratoga Medical (DBA Saratoga Ascend) is hiring Registered Nurses ... BLS/ACLS as required Schedule: 12-hour shifts | 3 shifts/week | Every other weekend | 13-week ...

Saratoga Medical

Registered Nurse

Turbeville, SC · On-site

Saratoga Medical (DBA Saratoga Ascend) is hiring Registered Nurses (RNs) for onsite opportunities ... BLS/ACLS as required Schedule: 12-hour shifts | 3 shifts/week | Every other weekend | 13-week ...

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Weekend Rn information

See Florence, SC salary details

$24

$38

$63

How much do weekend rn jobs pay per hour?

As of Sep 10, 2026, the average hourly pay for weekend rn in Florence, SC is $38.05, according to ZipRecruiter salary data. Most workers in this role earn between $30.20 and $43.92 per hour, depending on experience, location, and employer.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

More about Weekend Rn jobs

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Cities near Florence, SC with the most Weekend Rn job openings:

Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in Florence, SC as of September 2026, with employment types broken down into 61% Full Time, 15% Part Time, 22% Contract, and 2% Nights. Highlights an 98% In-person, and 2% Hybrid job distribution, with an average salary of $79,149 per year, or $38.1 per hour.

Hospice Weekend Nurse - Hospice Homecare

Florence, SC • On-site

McLeod Health
Hospitals • 5 - 10K employees
Learn more about McLeod Healthexternal

Other

Posted 8 days ago

McLeod Health rating

6.5

Company rating: 6.5 out of 10

Based on 133 frontline employees who took The Breakroom Quiz

614th of 898 rated healthcare providers

Job description


Hospice Weekend Nurse (RN) - Hospice Homecare
$15,000 Sign-On Bonus Available!
Join our Hospice Homecare team and make a meaningful difference in the lives of patients and families when they need compassionate care the most. We are seeking a dedicated Registered Nurse to provide after-hours hospice care and clinical support during weekend coverage.
Schedule
72 Hours Biweekly
  • Friday: 11:00 AM - 11:00 PM
  • Saturday: 7:00 AM - 7:00 PM
  • Sunday: 7:00 AM - 7:00 PM
  • Backup call required
Position Summary
The Weekend Hospice RN provides skilled nursing care and clinical support to hospice patients and families during weekends when the office is closed. This role is responsible for triaging after-hours calls, completing necessary visits, performing hospice admissions and starts of care when clinically appropriate, and ensuring patients receive timely, compassionate, high-quality care.
Key Responsibilities
  • Triage after-hours calls and assess patient needs.
  • Provide clinically appropriate home visits, including:
    • Symptom management visits
    • Crisis visits
    • Death visits
    • Other urgent, unplanned nursing visits
  • Complete hospice referrals, admissions, and starts of care during after-hours coverage when immediate hospice services are needed.
  • Deliver skilled nursing care according to the patient's plan of care and physician orders.
  • Monitor patient conditions and communicate significant changes to the interdisciplinary team.
  • Coordinate care across settings, including inpatient, respite, and routine home care services.
  • Maintain accurate and timely clinical documentation.
  • Demonstrate professionalism, empathy, teamwork, and exceptional customer service in all patient and family interactions.
  • The Weekend RN will cover areas in Clarendon, Florence, Cheraw and Dillon.
Qualifications Required
  • Current South Carolina RN License
  • Current South Carolina Driver's License and automobile insurance as required by law
  • Current BLS Certification
  • Active patient care experience within the past year
  • Minimum of 1-2 years of RN experience
Preferred
  • Hospice experience
  • Home Health experience
  • Palliative Care experience
  • Medical-Surgical nursing experience

Ideal Candidate
The successful candidate will be able to work independently during after-hours coverage, demonstrate sound clinical judgment, effectively triage patient needs, and provide compassionate end-of-life care while supporting patients and families through every stage of the hospice journey.
Apply today and become part of a team dedicated to enhancing quality of life through exceptional hospice care.
About Us
Founded in 1906, McLeod Health is a locally owned and managed, not for profit organization supported by the strength of more than 900 members on its medical staff and more than 2,900 licensed nurses. McLeod Health is also composed of approximately 15,000 team members and more than 90 physician practices throughout its 18-county service area. With seven hospitals, McLeod Health operates three Health and Fitness Centers, a Sports Medicine and Outpatient Rehabilitation Center, Hospice and Home Health Services. The system currently has 988 licensed beds, including Hospice and Behavioral Health. The hospitals within McLeod Health include: McLeod Regional Medical Center, McLeod Health Dillon, McLeod Health Loris, McLeod Health Seacoast, McLeod Health Cheraw, McLeod Health Clarendon and McLeod Behavioral Health.
About the Team
If you would enjoy working in a dynamic environment and are looking for an opportunity to become part of a stellar team of professionals, we invite you to apply online today. We are an equal opportunity employer.

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About McLeod Health

Sourced by ZipRecruiter

McLeod Health is the region's destination for medical excellence. Our excellence extends from the Midlands to the Coast along the border of North and South Carolina - serving more than one million people. As medical needs grow - we grow, expand, and improve our facilities and services. The McLeod Health network is comprised of 7 hospitals with locations in Florence, Darlington, Dillon, Manning, Cheraw, Loris, and Little River. We have also expanded into the Carolina Forest area of Myrtle Beach for patients looking for primary care and family physicians. Founded over a century ago, McLeod is a locally owned, not-for-profit healthcare system which features the strength of more than 800 physicians and 2,000 registered nurses, and more than 8,500 employees. McLeod constantly seeks to improve patient care with efforts that are physician led, data-driven and evidence-based.

Industry

Hospitals

Company size

5,001 - 10,000 Employees

Headquarters location

Florence, SC, US

Year founded

1906

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