1

Weekend Rn Jobs in Florence, SC (NOW HIRING)

Stackable shift differentials: nights (+$6.00), weekends (+$4.00) * Up to $25,000 Sign-On Bonus * Relocation assistance available Registered Nurse Job Opportunity: * Registered Nurse seeks to provide ...

Stackable shift differentials: nights (+$6.00), weekends (+$4.00) * Up to $25, 000 Sign-On Bonus * Relocation assistance available Registered Nurse Job Opportunity: * Registered Nurse seeks to ...

next page

Showing results 1-20

Weekend Rn information

See Florence, SC salary details

$24

$38

$63

How much do weekend rn jobs pay per hour?

As of Jul 10, 2026, the average hourly pay for weekend rn in Florence, SC is $38.05, according to ZipRecruiter salary data. Most workers in this role earn between $30.20 and $43.92 per hour, depending on experience, location, and employer.

What are the chillest nursing jobs?

Weekend RNs often find the most relaxed nursing roles in outpatient clinics, telehealth, or home health care, which typically involve less emergency or high-stress situations. These positions usually offer flexible schedules, allowing nurses to work weekends and maintain a better work-life balance. Certifications like BLS and good communication skills are beneficial in these settings.

What Does a Weekend RN Do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

Can you make $50 an hour as a nurse?

Weekend RNs can potentially earn $50 an hour or more, especially with specialized skills, certifications, or working in high-demand areas. However, pay rates vary based on location, facility, experience, and shift differentials, and some positions may offer higher wages for weekend or night shifts.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

How to make $150,000 as a nurse?

To earn $150,000 as a Weekend RN, gaining experience in high-demand specialties like critical care or anesthesia can help, as these often offer higher pay. Working overtime, taking on additional shifts, or obtaining certifications such as CCRN or CRNA can also increase earning potential, especially in settings that pay premium rates for weekend coverage.
What are the most commonly searched types of Rn jobs in Florence, SC? The most popular types of Rn jobs in Florence, SC are:
What are popular job titles related to Weekend Rn jobs in Florence, SC? For Weekend Rn jobs in Florence, SC, the most frequently searched job titles are:
What job categories do people searching Weekend Rn jobs in Florence, SC look for? The top searched job categories for Weekend Rn jobs in Florence, SC are:
What cities near Florence, SC are hiring for Weekend Rn jobs? Cities near Florence, SC with the most Weekend Rn job openings:
Weekend Registered Nurse (RN) MUSC Florence Inpatient Oncology - FT Days

Weekend Registered Nurse (RN) MUSC Florence Inpatient Oncology - FT Days

Medical University of South Carolina

Florence, SC • On-site

Other

Medical, Retirement

Re-posted 9 days ago


Job description

Job Description Summary
Outstanding opportunity for an experienced Registered Nurse interested in a Weekend Only Program. Eligible for full-time benefits and shift differentials. Please contact Recruiter Shannon Shaw at 843-674-2694 or shawsh@musc.edu for more information!
Entity
Medical University Hospital Authority (MUHA)
Worker Type
Employee
Worker Sub-Type
Regular
Cost Center
CC003592 FLO - MedSurg 6th Floor (FMC)
Pay Rate Type
Hourly
Pay Grade
Health-28
Scheduled Weekly Hours
36
Work Shift
Job Description
MUSC Florence is looking for experienced Registered Nurses to join their Weekend Option Program - Inpatient Oncology Unit
Schedule
  • 36 hours per week; choose between a schedule of Friday, Saturday, Sunday or Saturday, Sunday, Monday.
  • Day and Night shift opportunities available.
Incentives
  • Up to $25,000 RN Student Loan Repayment for those who qualify
  • Tuition Reimbursement Program if you would like to further your education
  • Great State Health Benefits and Retirement Plan
  • Up to 6 weeks paid parental leave
  • Free Telehealth appointments for you and your family
  • Onsite Pharmacy
  • Education Assistance
Registered Nurses for non-MAGNET facilities. Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and environmental needs. This includes providing for the assessment, development of nursing diagnoses, outcome identification, planning, implementation of interventions, coordination of care, health teaching and promotion and evaluation of goals and interventions consistent with the policies of MUSC. Maintains a safe, therapeutic, and healing environment through ensuring patient privacy and responsive, respectful, accepting, and professional behavior. Demonstrates the ability to function in a professional setting through active participation in a professional practice model. This includes participating in shared governance, adherence to standards of care, participation in peer review and professional development promoting leadership and clinical excellence, effective team skills, autonomous practice and acknowledgment of accountability for actions and critical thinking. Coordinates the effective and efficient delivery of patient care services through the application of care management principles. Identifies clinical priorities and initiates action to improve patient outcomes. Demonstrates ability to function in a professional practice model through active participation in shared governance, promotion of a healthy work environment and acceptance of personal responsibility for professional growth.
Additional Job Description
Minimum Requirements: Associate's Degree, and a minimum of one year of work experience as a registered nurse required. Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required.
Qualifications
  • South Carolina or compact state Registered Nurse license
  • BLS from the American Heart Association
  • Hospital RN experience preferred

Physical Requirements:
1. Ability to stand or sit for extended periods of time.
2. Proficiency in manual dexterity and fine motor skills for tasks such as taking patient vitals, administering injections, or conducting physical exams.
3. Capacity to lift and move patients or medical equipment as needed.
4. Visual acuity and color perception to accurately read medical charts, documents, and monitors.
5. Auditory ability to effectively communicate with patients and colleagues, as well as to perceive important sounds such as alarms or patient instructions.
6. Stamina and resilience to handle the physical and emotional demands of providing patient care, including long shifts and potentially stressful situations.
7. Mobility to navigate clinical environments, including moving between patient rooms, offices, and other areas of the facility.
8. Compliance with infection control protocols and proper use of personal protective equipment to maintain a safe and healthy work environment.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees