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Per Diem Rn Jobs in Florence, SC (NOW HIRING)

Shiftkey, LLC

RN

Fork, SC · On-site

$43/hr

ShiftKey enables independent Registered Nurses like you to bid on per diem RN shifts posted by a vast network of Healthcare Facilities--all based on criteria you select. Choose the facilities you ...

Shiftkey, LLC

RN

Florence, SC · On-site

$43/hr

ShiftKey enables independent Registered Nurses like you to bid on per diem RN shifts posted by a vast network of Healthcare Facilities--all based on criteria you select. Choose the facilities you ...

Shiftkey, LLC

RN

Scranton, SC · On-site

$36/hr

ShiftKey enables independent Registered Nurses like you to bid on per diem RN shifts posted by a vast network of Healthcare Facilities--all based on criteria you select. Choose the facilities you ...

eHospitalHire

Travel Nurse RN - Med Surg

Florence, SC · On-site

$2.9K/wk

Travel reimbursement and per diem allowances, Employee discounts, educational opportunities, and ... Refer a Registered Nurse for a $1000.00 bonus opportunity! eHospitalHire Job ID #723286. Pay ...

eHospitalHire

Travel Nurse RN - Med Surg

Florence, SC · On-site

$2.9K/wk

Travel reimbursement and per diem allowances, Employee discounts, educational opportunities, and ... Refer a Registered Nurse for a $1000.00 bonus opportunity! eHospitalHire Job ID #723287. Pay ...

HAN Staff

RN - Med-Surg

Florence, SC · On-site

$2.9K/wk

RN - MS/Tele Registered Nurse - EHospitalHire is urgently hiring MS/Tele RNs with at least 2 years ... Travel reimbursement and per diem allowances, Employee discounts, educational opportunities, and ...

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All JobsPer Diem Rn JobsPer Diem Rn Jobs in Florence, SC

Per Diem Rn information

See Florence, SC salary details

$5

$40

$74

How much do per diem rn jobs pay per hour?

As of Sep 5, 2026, the average hourly pay for per diem rn in Florence, SC is $40.19, according to ZipRecruiter salary data. Most workers in this role earn between $28.80 and $55.53 per hour, depending on experience, location, and employer.

What is a per diem RN?

A Per Diem RN is a registered nurse who works on an as-needed basis rather than having a set, full-time schedule. These nurses fill staffing gaps, cover for absences, or help during busy periods at hospitals, clinics, or other healthcare facilities. Per diem RNs often have flexibility in choosing their shifts, but they may not receive the same benefits as full-time staff. This role is ideal for nurses seeking variety and work-life balance.

What skills and qualifications are needed to thrive as a per diem RN?

To thrive as a Per Diem RN, you need a valid RN license, strong clinical assessment abilities, and experience across various healthcare settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS and ACLS are typically required. Flexibility, strong communication, and the ability to quickly adapt to different teams and environments are standout soft skills. These competencies are vital for delivering safe, effective care while efficiently integrating into new units with minimal orientation.

How does scheduling typically work for a per diem RN, and what level of flexibility can I expect?

As a Per Diem RN, you have the flexibility to choose your shifts based on your availability, which makes this role ideal for those seeking work-life balance or supplemental income. Scheduling is often managed through online portals or direct communication with nurse managers, and you may be asked to fill shifts on short notice to cover staff shortages or peak periods. While you have control over your schedule, keep in mind that the most shifts are often available during weekends, holidays, or less desirable hours. Building strong relationships with staffing coordinators and being open to various shifts can help you secure more consistent work.

What is the difference between Per Diem Rn vs Staff Nurse?

AspectPer Diem RnStaff Nurse
CredentialsRegistered Nurse (RN) licenseRegistered Nurse (RN) license
Work EnvironmentVaries daily, short-term assignments, flexible schedulingFull-time or part-time hospital or clinic settings, consistent schedule
Employment TypePer diem, as-needed basisPermanent or temporary staff position
UsageSupplemental staffing, fill-in shiftsPrimary nursing staff in healthcare facilities

Per Diem Rns are registered nurses working on a flexible, as-needed basis, often filling in for staff shortages or covering shifts temporarily. Staff Nurses typically hold full-time or part-time positions with consistent schedules in healthcare facilities. The main difference lies in employment type and scheduling flexibility, with Per Diem Rns offering more adaptability compared to the steady employment of Staff Nurses.

What are the most commonly searched types of Rn jobs in Florence, SC?

The most popular types of Rn jobs in Florence, SC are:

What are popular job titles related to Per Diem Rn jobs in Florence, SC?

For Per Diem Rn jobs in Florence, SC, the most frequently searched job titles are:

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The top searched job categories for Per Diem Rn jobs in Florence, SC are:

What cities near Florence, SC are hiring for Per Diem Rn jobs?

Cities near Florence, SC with the most Per Diem Rn job openings:

Per Diem Rn jobs near you
Infographic showing various Per Diem Rn job openings in Florence, SC as of August 2026, with employment types broken down into 50% Full Time, and 50% Part Time. Highlights an 100% In-person job distribution, with an average salary of $83,603 per year, or $40.2 per hour.

Registered Nurse (RN) - PRN/Per Diem

Regency Hospital - Florence

Florence, SC • On-site

$53/hr

Per diem

Life, Retirement

Re-posted 8 days ago

Job description

Overview
Position: Registered Nurse (RN)
Location: Regency Hospital - Florence
Schedule: PRN/Per Diem - 12 hour shifts - Days or Nights availableCompensation: $53.00 per hour
Sign-On Bonus: $5,000 Nights Only
Regency Hospital - Florence is a critical illness recovery hospital committed to providing world-class inpatient post-ICU services to chronic, critically ill patients who require extended healing and recovery. We help patients during some of the most vulnerable, painful moments of their lives - and Registered Nurses (RNs) play a central role in providing compassionate, excellent treatment every step of the way.
At our company, we support your career growth and personal well-being.
  • Start Strong: Extensive orientation program to ensure a smooth transition into our setting.
  • Opportunity for Advancement: Demonstrate your skills and dedication which could lead to potential full-time opportunities
  • Foster Well-being: We offer benefits which support the financial, work/life and emotional well-being of you and your family members. Part time/Per Diem positions are eligible for 401k based on reaching 1,000 hours within their first anniversary or subsequent calendar year. We also offer our employee assistance program to part time employees.
  • Your Impact Matters: Join a team of over 44,000 committed to providing exceptional patient care

Responsibilities
  • Receive admissions and/or transfers to the unit
  • Initial and ongoing systematic patient assessment
  • Timely and accurate documentation using appropriate systems
  • Interpret assessment/diagnostic data including labs and telemetry
  • Ensure medical orders are transcribed and processed accurately
  • Competence in Rapid Response and code events
  • Instruct and counsel patients/families
  • Performs other duties as assigned

Qualifications
Minimum Qualifications:
  • Valid State RN License
  • BLS is required at hire.
  • ACLS is required at hire.

Preferred Qualifications:
  • Clinical experience

Additional Data
Equal Opportunity Employer/including Disabled/Veterans

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