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Per Diem Rn Jobs in Greenville, SC (NOW HIRING)

Shiftkey, LLC

RN

Greenville, SC · On-site

$44/hr

ShiftKey enables independent Registered Nurses like you to bid on per diem RN shifts posted by a vast network of Healthcare Facilities--all based on criteria you select. Choose the facilities you ...

Shiftkey, LLC

RN

Spartanburg, SC · On-site

$40/hr

ShiftKey enables independent Registered Nurses like you to bid on per diem RN shifts posted by a vast network of Healthcare Facilities--all based on criteria you select. Choose the facilities you ...

New

Shiftkey, LLC

RN

Easley, SC · On-site

$44/hr

ShiftKey enables independent Registered Nurses like you to bid on per diem RN shifts posted by a vast network of Healthcare Facilities--all based on criteria you select. Choose the facilities you ...

New

Shiftkey, LLC

RN

Inman, SC · On-site

$37/hr

ShiftKey enables independent Registered Nurses like you to bid on per diem RN shifts posted by a vast network of Healthcare Facilities--all based on criteria you select. Choose the facilities you ...

New

Shiftkey, LLC

RN

Travelers Rest, SC · On-site

$45/hr

ShiftKey enables independent Registered Nurses like you to bid on per diem RN shifts posted by a vast network of Healthcare Facilities--all based on criteria you select. Choose the facilities you ...

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All JobsPer Diem Rn JobsPer Diem Rn Jobs in Greenville, SC

Per Diem Rn information

See Greenville, SC salary details

$4

$36

$67

How much do per diem rn jobs pay per hour?

As of Sep 4, 2026, the average hourly pay for per diem rn in Greenville, SC is $36.58, according to ZipRecruiter salary data. Most workers in this role earn between $26.20 and $50.53 per hour, depending on experience, location, and employer.

What is a per diem RN?

A Per Diem RN is a registered nurse who works on an as-needed basis rather than having a set, full-time schedule. These nurses fill staffing gaps, cover for absences, or help during busy periods at hospitals, clinics, or other healthcare facilities. Per diem RNs often have flexibility in choosing their shifts, but they may not receive the same benefits as full-time staff. This role is ideal for nurses seeking variety and work-life balance.

What skills and qualifications are needed to thrive as a per diem RN?

To thrive as a Per Diem RN, you need a valid RN license, strong clinical assessment abilities, and experience across various healthcare settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS and ACLS are typically required. Flexibility, strong communication, and the ability to quickly adapt to different teams and environments are standout soft skills. These competencies are vital for delivering safe, effective care while efficiently integrating into new units with minimal orientation.

How does scheduling typically work for a per diem RN, and what level of flexibility can I expect?

As a Per Diem RN, you have the flexibility to choose your shifts based on your availability, which makes this role ideal for those seeking work-life balance or supplemental income. Scheduling is often managed through online portals or direct communication with nurse managers, and you may be asked to fill shifts on short notice to cover staff shortages or peak periods. While you have control over your schedule, keep in mind that the most shifts are often available during weekends, holidays, or less desirable hours. Building strong relationships with staffing coordinators and being open to various shifts can help you secure more consistent work.

What is the difference between Per Diem Rn vs Staff Nurse?

AspectPer Diem RnStaff Nurse
CredentialsRegistered Nurse (RN) licenseRegistered Nurse (RN) license
Work EnvironmentVaries daily, short-term assignments, flexible schedulingFull-time or part-time hospital or clinic settings, consistent schedule
Employment TypePer diem, as-needed basisPermanent or temporary staff position
UsageSupplemental staffing, fill-in shiftsPrimary nursing staff in healthcare facilities

Per Diem Rns are registered nurses working on a flexible, as-needed basis, often filling in for staff shortages or covering shifts temporarily. Staff Nurses typically hold full-time or part-time positions with consistent schedules in healthcare facilities. The main difference lies in employment type and scheduling flexibility, with Per Diem Rns offering more adaptability compared to the steady employment of Staff Nurses.

What are the most commonly searched types of Rn jobs in Greenville, SC?

The most popular types of Rn jobs in Greenville, SC are:

What are popular job titles related to Per Diem Rn jobs in Greenville, SC?

For Per Diem Rn jobs in Greenville, SC, the most frequently searched job titles are:

What job categories do people searching Per Diem Rn jobs in Greenville, SC look for?

The top searched job categories for Per Diem Rn jobs in Greenville, SC are:

What cities near Greenville, SC are hiring for Per Diem Rn jobs?

Cities near Greenville, SC with the most Per Diem Rn job openings:

Per Diem Rn jobs near you
Infographic showing various Per Diem Rn job openings in Greenville, SC as of August 2026, with employment types broken down into 3% As Needed, 55% Full Time, 15% Part Time, and 27% Contract. Highlights an 98% Physical, and 2% Remote job distribution, with an average salary of $76,076 per year, or $36.6 per hour.

RN

Shiftkey, LLC

Greenville, SC • On-site

$44/hr

Other

Medical, Dental, Vision, Life

Posted 18 days ago

Job description

Build your own schedule. Take control of your career.

Looking for RN jobs that fit your life? If you're tired of having no control over your schedule or just want to earn more money, PRN shifts could be what you're looking for! ShiftKey enables independent Registered Nurses like you to bid on per diem RN shifts posted by a vast network of Healthcare Facilities—all based on criteria you select. Choose the facilities you want, on days you want, and bid the rate you want.

  • Better work/life balance - Don't want to work nights? Need Mondays off? Only want to work once in a while? No problem. Use ShiftKey to work as little or as much as you like.
  • Extra income - Use ShiftKey to pick up shifts whenever you need a little extra money, even if you have another job. Get paid the next day with a PayCard or go with weekly direct deposit.
  • Pick the right environment for you - PRN shifts are a great way to experience a variety of facilities.

ShiftKey partners with Stride Health to allow healthcare professionals who use the ShiftKey App to access Stride's portable benefits platform for affordable healthcare options such as:

  • Health
  • Dental
  • Vision
  • Life Insurance

Role Requirements:

  • A high school diploma or GED.
  • A valid registered nurse license in the state of South Carolina.

About the Role:

You know better than anyone that RNs are essential members of a facility's medical team. Your role is to keep patients in the know and on the road to recovery. Here are a few things you might do:

  • Perform and interpret diagnostic tests.
  • Prepare patients for treatments.
  • Administer medications.
  • Maintain and document medical records.
  • Counsel patients and their families on how to manage medical issues.

Here's what ShiftKey users have to say about us:

"This was one of the best choices I've made as a nurse. I love the freedom I have now!!" - LVN, Dallas, TX

"Amazing! You make your own schedule. You get daily pay or weekly. And they always respond when you need them." - CNA, Springfield, TN

"I've been using ShiftKey for years. It's a very good way to work. The people and facilities are respectful and helpful." - CNA, Kansas City, MO

ShiftKey logo

About ShiftKey

Sourced by ZipRecruiter

ShiftKey, founded in Dallas, Texas, is a trailblazer in the healthcare staffing and tech industry. Established with a missive to reinvent healthcare staffing, the company operates an innovative platform that enables healthcare facilities to directly engage with professionals on a 24/7 basis, bypassing the traditional agency model. The core values are centered around improving access to healthcare jobs, paying professionals better, and giving them more control over their work schedules.

Industry

Software development

Company size

51 - 200 Employees

Headquarters location

Dallas, TX, US

Year founded

2016

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