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Weekend Rn Jobs in Charleston, SC (NOW HIRING)

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

... some weekends Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager. Under ... general supervision, the Registered Nurse II provides individualized, goal-directed patient care to ...

Summary The Registered Nurse II on the NSICU Unit reports to the Nurse Manager. Under general ... weekends Job Summary/Purpose : The Neuroscience Intensive Care was designed and organized to meet ...

Summary The Registered Nurse II on the NSICU Unit reports to the Nurse Manager. Under general ... weekends Job Summary/Purpose : The Neuroscience Intensive Care was designed and organized to meet ...

Summary The Registered Nurse II on the NSICU Unit reports to the Nurse Manager. Under general ... weekends Job Summary/Purpose : The Neuroscience Intensive Care was designed and organized to meet ...

Summary The Registered Nurse II on the NSICU Unit reports to the Nurse Manager. Under general ... weekends Job Summary/Purpose : The Neuroscience Intensive Care was designed and organized to meet ...

Summary The Registered Nurse II on the NSICU Unit reports to the Nurse Manager. Under general ... weekends Job Summary/Purpose : The Neuroscience Intensive Care was designed and organized to meet ...

Summary The Registered Nurse II on the NSICU Unit reports to the Nurse Manager. Under general ... weekends Job Summary/Purpose : The Neuroscience Intensive Care was designed and organized to meet ...

Summary The Registered Nurse II on the NSICU Unit reports to the Nurse Manager. Under general ... weekends Job Summary/Purpose : The Neuroscience Intensive Care was designed and organized to meet ...

Summary The Registered Nurse II on the NSICU Unit reports to the Nurse Manager. Under general ... weekends Job Summary/Purpose : The Neuroscience Intensive Care was designed and organized to meet ...

Summary The Registered Nurse II on the NSICU Unit reports to the Nurse Manager. Under general ... weekends Job Summary/Purpose : The Neuroscience Intensive Care was designed and organized to meet ...

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Weekend Rn information

See Charleston, SC salary details

$25

$40

$68

How much do weekend rn jobs pay per hour?

As of May 30, 2026, the average hourly pay for weekend rn in Charleston, SC is $40.73, according to ZipRecruiter salary data. Most workers in this role earn between $32.32 and $47.02 per hour, depending on experience, location, and employer.

What Does a Weekend RN Do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

How to make an extra $1000 a month as a nurse?

Weekend RNs can increase their income by taking on additional shifts, working overtime, or picking up per diem assignments. Gaining specialized certifications, such as in IV therapy or wound care, can also qualify you for higher-paying roles or agency work, helping you reach your income goal more quickly.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What are the most commonly searched types of Rn jobs in Charleston, SC? The most popular types of Rn jobs in Charleston, SC are:
What are popular job titles related to Weekend Rn jobs in Charleston, SC? For Weekend Rn jobs in Charleston, SC, the most frequently searched job titles are:
What job categories do people searching Weekend Rn jobs in Charleston, SC look for? The top searched job categories for Weekend Rn jobs in Charleston, SC are:
What cities near Charleston, SC are hiring for Weekend Rn jobs? Cities near Charleston, SC with the most Weekend Rn job openings:
Infographic showing various Weekend Rn job openings in Charleston, SC as of May 2026, with employment types broken down into 3% As Needed, 56% Full Time, 36% Part Time, and 5% Contract. Highlights an 97% In-person, and 3% Remote job distribution, with an average salary of $84,721 per year, or $40.7 per hour.
RN

Full-time

Posted 1 hour ago


MUSC Health rating

6.8

Company rating: 6.8 out of 10

Based on 192 frontline employees who took The Breakroom Quiz

488th of 864 rated healthcare providers


Job description

Job Description Summary

The Registered Nurse II reports to the Nurse Manager. Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired outcomes.

Entity

Medical University Hospital Authority (MUHA)

Worker Type

Employee

Worker Sub-Type​

Regular

Cost Center

CC000513 CHS - MedSurg - Neuro 8W (Main)

Pay Rate Type

Hourly

Pay Grade

Health-28

Scheduled Weekly Hours

36

Work Shift

Job Description

Job Description

Entity/Organization:  MUHA (Medical University Hospital Authority/Medical Center)

Hours Per Week:   36

Scheduled Work Hours/Shift:  3 - 12 Hour rotating shifts per week, including some weekends

Job Summary/Purpose: The Registered Nurse II reports to the Nurse Manager.  Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired outcomes.

Minimum Training and Education:  Bachelor of Nursing degree preferred. RN staff hired on or after July 1, 2013 with an Associate or Diploma degree in nursing are required to be enrolled in an accredited BSN program within two years and successfully obtain a BSN degree within four years of the RN hire or reclassification date. Refer to policy A141 for more details. A minimum of one year of work experience as a registered nurse required.

Required Licensure, Certifications, Registrations:  Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required, either a certification from an American Heart Association (AHA) BLS for Healthcare Providers (or AHA recognized equivalent) or an American Red Cross CPR/AED for Professional Rescuer and Healthcare Provider.

Additional Job Description

Physical and Mental Requirements:  Ability to perform job functions while standing. (Continuous) Ability to perform job functions while sitting. (Continuous) Ability to perform job functions while walking. (Continuous) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work outside in temperature extremes. (Infrequent) Ability to work from elevated areas. (Frequent) Ability to work in confined/cramped spaces. (Frequent) Ability to perform job functions from kneeling positions. (Infrequent) Ability to bend at the waist. (Continuous) Ability to twist at the waist. (Frequent) Ability to squat and perform job functions. (Frequent) Ability to perform "pinching" operations. (Frequent) Ability to perform gross motor activities with fingers and hands. (Continuous) Ability to perform firm grasping with fingers and hands. (Continuous) Ability to perform fine manipulation with fingers and hands. (Continuous) Ability to reach overhead. (Frequent) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to use lower extremities for balance and coordination. (Frequent) Ability to reach in all directions. (Continuous) Ability to lift and carry 50 lbs. unassisted. (Infrequent) Ability to lift/lower objects 50 lbs. from/to floor from/to 36 inches unassisted. (Infrequent) Ability to lift from 36" to overhead 25 lbs. (Infrequent) Ability to exert up to 50 lbs. of force. (Frequent) Examples include: To transfer a 100 lb. patient that can not assist in the transfer requires 50 lbs. of force. For every 100 additional pounds, assistance will be required from another healthcare worker. 20 lbs. of force is needed to push a 400 lb. patient in a wheelchair on carpet. 25 lbs. of force is required to push a stretcher with a patient with one hand. Ability to maintain 20/40 vision, corrected, in one eye or with both eyes. (Continuous) Ability to see and recognize objects close at hand or at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to deal effectively with stressful situations. (Continuous) Ability to work rotating shifts. (Frequent) Ability to work overtime as required. (Frequent) Ability to work in a latex safe environment. (Continuous) Ability to maintain tactile sensory functions. (Continuous) (Selected Positions) *Ability to maintain good olfactory sensory function. (Continuous) *(Selected Positions) *Ability to be qualified physically for respirator use, initially and as required. (Continuous) (Selected Positions)

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees


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About MUSC Health

Sourced by ZipRecruiter

MUSC is located in Charleston, SC, frequently named one of the best places in America to live. If charming, historic, vibrant, cultural, and coastal are adjectives that you find appealing, it's all here. In Charleston, you might find yourself dining at a world class restaurant tonight and relaxing on a boat as you explore our many waterways tomorrow. You might stroll along cobblestone streets, amidst centuries old homes by day and attend a jazz concert by night. Charleston is a place where you can live your life to its fullest.

Industry

Hospitality services

Company size

10,000+ Employees

Headquarters location

Charleston, SC, US

Year founded

1824