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How much do reference laboratory jobs pay per year?

As of Aug 20, 2026, the average yearly pay for reference laboratory in the United States is $96,784.00, according to ZipRecruiter salary data. Most workers in this role earn between $65,000.00 and $131,500.00 per year, depending on experience, location, and employer.

What is a reference laboratory?

A Reference Laboratory job typically involves performing specialized diagnostic testing that may not be available in a standard clinical laboratory. Professionals in this field analyze complex specimens, ensure accuracy and quality control, and provide critical data for medical diagnosis and treatment. These labs often handle tests referred by hospitals, clinics, and physicians that require advanced equipment and expertise. Employees may work in roles such as laboratory technicians, technologists, or scientists, depending on their qualifications and experience.

What are the typical daily responsibilities of a reference laboratory professional?

As a Reference Laboratory professional, your daily responsibilities generally include performing specialized diagnostic tests, analyzing specimens, validating test results, and maintaining accurate records in laboratory systems. You may also be responsible for operating and troubleshooting complex laboratory equipment, adhering to strict quality control protocols, and ensuring compliance with regulatory standards. Collaboration with physicians, researchers, and other laboratory personnel is common to ensure that test results are interpreted accurately and delivered promptly. These tasks help maintain the high accuracy and reliability that medical providers and patients depend on in specialized testing.

What are the key skills and qualifications needed to thrive in a reference laboratory position?

To thrive in a Reference Laboratory position, you need a strong background in laboratory sciences, attention to detail, and expertise in diagnostic testing, usually supported by a degree in medical laboratory science or a related field. Familiarity with laboratory information management systems (LIMS), automated analyzers, and relevant certifications like ASCP or equivalent are typically required. Strong analytical thinking, effective communication, and teamwork skills help professionals excel in this environment. These abilities are vital for ensuring accurate, timely results and maintaining quality standards essential for patient care and research.

What does a reference laboratory do?

A reference laboratory performs specialized testing and analysis on biological samples to confirm diagnoses, support public health, and ensure quality control. They often handle complex or confirmatory tests that are beyond the scope of standard laboratories and require advanced equipment and expertise.
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Reference Laboratory jobs near you
Infographic showing various Reference Laboratory job openings in the United States as of August 2026, with employment types broken down into 2% As Needed, 77% Full Time, 15% Part Time, and 6% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $96,784 per year, or $46.5 per hour.

Laboratory Scientist- Immunohematology Reference Lab- Second Shift

Versiti, Inc.

Indianapolis, IN • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 11 days ago

Versiti rating

5.7

Company rating: 5.7 out of 10

Based on 46 frontline employees who took The Breakroom Quiz

787th of 889 rated healthcare providers

Job description

Overview
Versiti is a fusion of donors, scientific curiosity, and precision medicine that recognize the gifts of blood and life are precious. We are home to the world-renowned Blood Research Institute, we enable life saving gifts from our donors, and provide the science behind the medicine through our diagnostic laboratories. Versiti brings together outstanding minds with unparalleled experience in transfusion medicine, transplantation, stem cells and cellular therapies, oncology and genomics, diagnostic lab services, and medical and scientific expertise. This combination of skill and knowledge results in improved patient outcomes, higher quality services and reduced cost of care for hospitals, blood centers, hospital systems, research and educational institutions, and other health care providers. At Versiti, we are passionate about improving the lives of patients and helping our healthcare partners thrive.
Position Summary
Under direction of the Manager of Immunohematology Reference Laboratory, performs advanced immunohematology testing on clinical and research specimens for the resolution of serologic problems and provides the correct blood product for transfusion based on these results. Performs and interprets molecular testing on clinical and research specimens if applicable to the laboratory. Perform blood product component preparation if applicable to the laboratory. Provides the most appropriate blood in a timely and accurate manner and provides phone consultation to customers.
Total Rewards Package
Compensation
The target salary is based on internal averages. Versiti sets salary ranges aligned to local markets in which the job is performed. Compensation decisions take into account internal salary averages and differentiation based on education, experience, skills, and performance. Specific salary and benefits information is shared at the time of the phone screening based on your location and qualifications.
Benefits
Versiti provides a comprehensive benefits package based on your job classification. Full-time regular employes are eligible for Medical, Dental, and Vision Plans, Paid Time Off (PTO) and Holidays, Short- and Long-term disability, life insurance, 7% match dollar for dollar 401(k), voluntary programs, discount programs, others.
Responsibilities
  • Handles and processes specimens, ensuring proper identification.
  • Performs serologic and molecular tests according to SOP on clinical, study, QC and research samples.
  • Recognizes and resolves procedural discrepancies in testing results.
  • Interprets laboratory results.
  • Reports laboratory results.
  • Maintains accurate and complete records.
  • Perform reagent preparation
  • Operates laboratory equipment correctly and perform quality control testing on equipment and reagents. Knows acceptable levels of performance.
  • Maintains controlled inventories of reagents and laboratory materials.
  • Performs secondary review and release of test results and provides feedback to ensure accurate reporting of results.
  • Adheres to all required FDA, AABB (American Association of Blood Banks),CLIA (Clinical Laboratory Improvement Act), OSHA (Occupational Safety and Health Administration), and CAP (College of American Pathology) regulations. Follows cGMP (current Good Manufacturing Practices) standards.
  • Support implementation and validation of new tests/equipment.
  • Assists in the training of new personnel and training of students.
  • Assess competence of clinical diagnostic lab staff if applicable
  • Provides on call and/or overtime coverage as required.
  • Listens, anticipates and responds to the needs of internal and external customers and strives to meet expectations.
  • Communicates clearly, accurately and respectfully with customers, donors, and colleagues, ensuring that necessary information is shared.
  • Notifies management or other appropriate persons of problems or issues as appropriate.
  • Works effectively with inter or intra-department(s) and project teams to meet customer needs and organizational goals.
  • Participates in quality and process improvement.
  • Supports and promotes Versiti mission and values, both at work and in the community.
  • Performs other duties as required or assigned which are reasonably within the scope of the duties in this job classification
  • Complies with all policies and standards

Qualifications
Education
  • Bachelor's Degree from an accredited college or university in Clinical Laboratory Science required
  • Medical Technology (MLS/CLS/MT) required
  • or science related degree with certification as a BB technologist required

Experience
  • 1-3 years experience working in an Immunohematology reference laboratory or transfusion service preferred

Knowledge, Skills and Abilities
  • Working knowledge of immunohematology and immunology theory.
  • Skill in the operation of laboratory equipment, instrument, computer and materials.
  • Effective time managing and organizational skills to perform multiple laboratory tests simultaneously.
  • Maintain accurate, timely records of patient information and laboratory results.
  • Strong detail orientation and analytical ability to evaluate and ensure accuracy of data related to laboratory results and patient information.
  • Effective verbal and written communication skills, including the ability to convey understanding of factual and theoretical information and make recommendations to customers.
  • Effective problem-solving skills.
  • Ability to work independently and as a team member.

Licenses and Certifications
  • MLS/CLS/MT/BB American Society for Clinical Pathologist (ASCP) certification required or equivalent required
  • Or; two-year degree from an accredited college, university or technical college in a Medical Laboratory Technician program with an MLT certification and 4-6 years of IRL experience required

Tools and Technology
  • Personal Computer (desktop, laptop, tablet) required
  • General office equipment (computer, printer, fax, copy machine) required
  • Microsoft Suite (Word, Excel, PowerPoint) required
  • General laboratory equipment including centrifuges, automated cell washers and incubator/waterbaths for performing clinical tests. required
  • Molecular instrumentation such as light cyclers required
  • Pipettes (single channel, multi-channel, electronic, etc.) required
  • pH meter, microscopes required

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