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Protein Crystallography Jobs (NOW HIRING)

Amgen SA

$67K - $92K/yr

Work closely with structural biologists to generate high-quality protein samples for structural biology techniques, particularly X-ray crystallography and cryo-EM. * Method Development: Develop and ...

Amgen

Senior Scientist - Protein Biochemist

Thousand Oaks, CA · On-site

$96K - $131K/yr

Work closely with structural biologists to generate high-quality protein samples for structural biology techniques, particularly X-ray crystallography and cryo-EM. * Method Development: Develop and ...

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How much do protein crystallography jobs pay per hour?

As of Sep 10, 2026, the average hourly pay for protein crystallography in the United States is $37.89, according to ZipRecruiter salary data. Most workers in this role earn between $25.00 and $47.60 per hour, depending on experience, location, and employer.

What is protein crystallography?

A Protein Crystallography job involves determining the 3D structures of proteins using X-ray crystallography or cryo-electron microscopy. Scientists in this role grow protein crystals, collect diffraction data, and analyze molecular structures to understand protein function. These insights are critical for drug design, enzyme engineering, and fundamental biological research. Positions are typically found in academia, pharmaceuticals, and biotechnology companies. Strong skills in structural biology, biochemistry, and computational modeling are often required.

What are the main challenges faced in a protein crystallography role, and how can they be addressed?

One of the primary challenges in Protein Crystallography is obtaining high-quality protein crystals, as this process often requires extensive optimization and troubleshooting. Additionally, interpreting diffraction data and solving complex protein structures can be time-consuming and may involve overcoming technical hurdles. Collaborating closely with colleagues in molecular biology, bioinformatics, and computational chemistry is essential for success. Staying persistent and adaptable, and seeking mentorship from experienced team members, can help navigate these challenges and lead to successful outcomes in structural biology projects.

What are the key skills and qualifications needed to thrive in protein crystallography, and why are they important?

To thrive in Protein Crystallography, you need expertise in molecular biology, protein purification, crystallization techniques, and structural biology, typically supported by an advanced degree in biochemistry or a related field. Familiarity with X-ray diffraction equipment, data analysis software (such as CCP4, Phenix, or Coot), and lab management systems is essential. Attention to detail, problem-solving abilities, and strong collaboration skills are key soft skills for effective research and teamwork. These competencies ensure accurate structural analysis, smooth laboratory operations, and valuable contributions to scientific discovery.

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Protein Crystallography jobs near you
Infographic showing various Protein Crystallography job openings in the United States as of September 2026, with employment types broken down into 33% Full Time, 33% Part Time, and 34% Contract. Highlights an 100% In-person job distribution, with an average salary of $78,821 per year, or $37.9 per hour.

Engineer- Embodied AI Lab Automation: Vision-Guided Real Time Robotic Manipulation

Upton, NY • On-site

Brookhaven Science Associates, LLC
See more jobs at Brookhaven Science Associates, LLCexternal

$71K - $119K/yr

Other

Posted 22 days ago

Job description

Job Overview

Brookhaven National Laboratory’s National Synchrotron Light Source II (NSLS-II) is seeking an engineer to develop an automated protein crystal harvesting system at the Center for BioMolecular Structure (CBMS). This 2‑year term position offers the possibility of renewal based on performance and funding availability.

Responsibilities
  • Develop and implement vision‑guided real‑time robotic manipulation methods for crystal harvesting.
  • Design and deploy closed‑loop perception and control pipelines using visual feedback.
  • Contribute to vision‑based servoing approaches for precise, real‑time positioning.
  • Integrate perception outputs with motion planning and execution using ROS2 and MoveIt2.
  • Perform system calibration (hand‑eye calibration, camera calibration) to ensure accurate 3D spatial alignment.
  • Evaluate and improve system robustness, including perception uncertainty and failure modes.
  • Collaborate closely with domain experts across crystallography, controls, and engineering.
  • Participate in system testing, tuning, and performance evaluation.
  • Document methods and results; contribute to reports, publications, and presentations.
Required Knowledge, Skills, and Abilities
  • B.S. in Robotics, Computer Science, Physics, Applied Mathematics, Mechanical Engineering, Electrical Engineering, or a related field.
  • Demonstrated experience developing and implementing robotics systems.
  • Strong programming skills in Python and/or C++.
  • Knowledge of robotic kinematics, coordinate transformations, motion planning, and trajectory generation.
  • Proficiency with calibration methods.
Preferred Knowledge, Skills, and Abilities
  • M.S. in Robotics, Computer Science, Physics, Applied Mathematics, Mechanical Engineering, Electrical Engineering, or a related field.
  • Experience developing robotic systems that integrate vision‑guided control in real‑world settings.
  • Proficiency with ROS2‑based ecosystems.
  • Experience with camera calibration, hand‑eye calibration, and coordinate frame registration.
  • Experience integrating machine learning models into robotics.
  • Familiarity with micro‑manipulation, sensor fusion or state estimation, real‑time system debugging, and performance tuning.
Success Measures
  • Development of a system capable of reliably detecting and localizing protein crystals.
  • Implementation of closed‑loop robotic manipulation using visual feedback.
  • Improved robustness and reliability of the crystal harvesting process under real‑world conditions.
Location & Compensation

On‑site position based at Brookhaven National Laboratory, Upton, New York. Salary range: $71,900—$119,000 per year, commensurate with experience. Benefits are available to all employees and details are provided upon request.

Equal Opportunity

Brookhaven National Laboratory is an Equal Employment Opportunity Employer and is committed to fostering a respectful and collaborative environment. All qualified individuals are encouraged to apply. Discrimination based on race, color, religion, sex, national origin, age, disability, or any other protected status is prohibited.

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