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Research Protein Purification Jobs (NOW HIRING)

Cogent Scientific

$100 - $125/hr

Cogent Scientific, an insourced contract research organization, is looking for the right people to ... We currently have a role available for a Protein Purification/Expression Biochemist to join our San ...

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Research Protein Purification information

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How much do research protein purification jobs pay per hour?

As of Sep 8, 2026, the average hourly pay for research protein purification in the United States is $22.22, according to ZipRecruiter salary data. Most workers in this role earn between $17.31 and $23.80 per hour, depending on experience, location, and employer.

What is research protein purification?

Research protein purification is the process of isolating a specific protein from a complex mixture, such as cells or tissues, for study or use in experiments. This process involves several steps, including extraction, separation, and analysis, to obtain a highly pure and functional protein. Protein purification is crucial in biochemical and pharmaceutical research, as it enables scientists to study protein structure, function, and interactions. Techniques used include chromatography, electrophoresis, and centrifugation, among others. Mastery of protein purification methods is essential for producing proteins for drug development, diagnostics, and basic research.

What are the key skills and qualifications needed to thrive in research protein purification?

To excel in Research Protein Purification, you need a solid background in biochemistry or molecular biology, hands-on laboratory experience, and a relevant degree such as a BSc, MSc, or PhD. Familiarity with chromatographic systems (e.g., FPLC, HPLC), protein characterization methods, and software for data analysis is typically required. Attention to detail, analytical thinking, and effective communication are crucial soft skills for troubleshooting and collaborating with research teams. These competencies ensure the reliable isolation and analysis of proteins, which are fundamental for advancing scientific research and therapeutic development.

What are some common challenges faced during protein purification in a research setting, and how can they be addressed?

One common challenge in research protein purification is maintaining protein stability and activity throughout the process, as proteins can denature or degrade easily. Another issue is achieving sufficient yield and purity, especially when working with low-expression proteins or complex mixtures. Overcoming these challenges often involves optimizing buffer conditions, choosing the right purification methods (such as affinity, ion-exchange, or size-exclusion chromatography), and troubleshooting at each step. Collaborating closely with colleagues in molecular biology, biochemistry, and analytical teams is also essential for problem-solving and method development.

What is the difference between Research Protein Purification vs Research Biochemistry Technician?

AspectResearch Protein PurificationResearch Biochemistry Technician
CredentialsBachelor's or Master's in Biochemistry, Molecular Biology, or related fieldsBachelor's degree in Biochemistry, Chemistry, or related sciences
Work EnvironmentLaboratories focused on protein isolation, purification, and analysisLaboratories conducting biochemical experiments, sample preparation, and analysis
Industry UsagePharmaceutical, biotech, academic researchResearch institutions, biotech companies, academic labs
Common Search/ComparisonResearch Protein PurificationResearch Biochemistry Technician

Research Protein Purification specialists focus specifically on isolating and purifying proteins for experiments, often requiring specialized techniques and equipment. Research Biochemistry Technicians perform broader biochemical tasks, including sample preparation and analysis. While both roles work in laboratory settings within similar industries, their core responsibilities and skill sets differ slightly, with protein purification being more specialized.

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What states have the most Research Protein Purification jobs?

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What job categories do people searching Research Protein Purification jobs look for?

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Research Protein Purification jobs near you
Infographic showing various Research Protein Purification job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $46,222 per year, or $22.2 per hour.

Scientist / Protein Purification

Pioneer Data

Cambridge, MA • On-site

Contractor

Posted 24 days ago

Job description

Position Details:
Our client, a world-leading Pharmaceutical Company in Cambridge, MA is currently looking for an Scientist to join their expanding team.
 
Job Title: Scientist / Protein Purification
Duration: 24 months contract, extendable up to 48 months
Location: Cambridge, MA
 
Note:
The client has the right-to-hire you as a permanent employee at any time during or after the end of the contract.
You may participate in the company group medical insurance plan
 
Job Description:
We are seeking a motivated Bench Scientist to join a biotherapeutics research team in Cambridge, MA.
This is a hands-on laboratory position focused primarily on recombinant protein expression, purification, and characterization to support downstream biotherapeutic research.

Key Responsibilities
Perform routine recombinant protein purification using FPLC/AKTA and related chromatography techniques.
Support the production of recombinant proteins and antigens for downstream biotherapeutic research.
Participate in protein expression workflows and, as needed, molecular biology/DNA-related activities.
Perform protein characterization and assess protein quality, purity, concentration, and suitability for downstream applications.
Work with antigens, antibodies, mAbs, Fabs, and other recombinant proteins.
Perform routine protein labeling and conjugation, including fluorescent and biotin labeling.
Assist with analytical techniques such as SDS-PAGE, Western blotting, and HPLC.
Maintain accurate laboratory records, sample tracking, and experimental documentation.
Manage multiple protein-production and purification requests while meeting project timelines.
Work collaboratively with scientists across the research organization and provide purified proteins for downstream studies.
Maintain a clean, organized, and compliant laboratory environment and follow all required laboratory safety and PPE procedures.

Required Qualifications
Bachelor's degree in Biochemistry, Biology, Chemistry, Molecular Biology, or a related scientific discipline.
At least 1 year of hands-on experience with recombinant protein purification or a closely related protein-science discipline.
Hands-on experience with AKTA/FPLC or comparable chromatography systems.
Understanding of protein purification and characterization principles.
Strong laboratory organization and time-management skills.
Ability to work effectively in a collaborative, fast-paced research environment.

Preferred Qualifications
Master's degree in Biochemistry, Biology, Biophysics, Molecular Biology, or a related field.
Experience with recombinant protein expression.
Experience with protein biophysics and protein characterization.
Experience working with antibodies, mAbs, Fabs, or recombinant antigens.
Background in immunology or biotherapeutic research.