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Research Protein Purification Jobs (NOW HIRING)

The HIHG Organized Research Lab is seeking a Research Associate 1 to work full-time, on-site in ... Execute protein purification. Perform Western blotting, ELISAs, and enzymatic and citotoxicity ...

Develop research findings and make recommendations to leadership for decision. Provide forward ... Column chromatography for protein purification by AEX, CEX, affinity, SEC, HIC. Column packing and ...

... research facility. PE is a multidisciplinary team with broad capabilities in protein engineering, expression, purification, and characterization. The ideal candidate should have a strong background ...

Protein expression, purification, and QC - 20% Express and purify polymerases, binders, and ... UAW Research About the UW Working at the University of Washington provides a unique opportunity to ...

Senior Scientist

Pearl River, NY

$93K - $128K/yr

... protein isolation, purification is expected. Qualifications QUALIFICATIONS AND SKILLS NEEDED: Masters or Bachelor in Biology, Biochemistry, Immunology or other related field with laboratory research ...

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Research Protein Purification information

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How much do research protein purification jobs pay per hour?

As of Jun 10, 2026, the average hourly pay for research protein purification in the United States is $22.22, according to ZipRecruiter salary data. Most workers in this role earn between $17.31 and $23.80 per hour, depending on experience, location, and employer.

What is the difference between Research Protein Purification vs Research Biochemistry Technician?

AspectResearch Protein PurificationResearch Biochemistry Technician
CredentialsBachelor's or Master's in Biochemistry, Molecular Biology, or related fieldsBachelor's degree in Biochemistry, Chemistry, or related sciences
Work EnvironmentLaboratories focused on protein isolation, purification, and analysisLaboratories conducting biochemical experiments, sample preparation, and analysis
Industry UsagePharmaceutical, biotech, academic researchResearch institutions, biotech companies, academic labs
Common Search/ComparisonResearch Protein PurificationResearch Biochemistry Technician

Research Protein Purification specialists focus specifically on isolating and purifying proteins for experiments, often requiring specialized techniques and equipment. Research Biochemistry Technicians perform broader biochemical tasks, including sample preparation and analysis. While both roles work in laboratory settings within similar industries, their core responsibilities and skill sets differ slightly, with protein purification being more specialized.

What are some common challenges faced during protein purification in a research setting, and how can they be addressed?

One common challenge in research protein purification is maintaining protein stability and activity throughout the process, as proteins can denature or degrade easily. Another issue is achieving sufficient yield and purity, especially when working with low-expression proteins or complex mixtures. Overcoming these challenges often involves optimizing buffer conditions, choosing the right purification methods (such as affinity, ion-exchange, or size-exclusion chromatography), and troubleshooting at each step. Collaborating closely with colleagues in molecular biology, biochemistry, and analytical teams is also essential for problem-solving and method development.

What is research protein purification?

Research protein purification is the process of isolating a specific protein from a complex mixture, such as cells or tissues, for study or use in experiments. This process involves several steps, including extraction, separation, and analysis, to obtain a highly pure and functional protein. Protein purification is crucial in biochemical and pharmaceutical research, as it enables scientists to study protein structure, function, and interactions. Techniques used include chromatography, electrophoresis, and centrifugation, among others. Mastery of protein purification methods is essential for producing proteins for drug development, diagnostics, and basic research.

What are the key skills and qualifications needed to thrive in Research Protein Purification, and why are they important?

To excel in Research Protein Purification, you need a solid background in biochemistry or molecular biology, hands-on laboratory experience, and a relevant degree such as a BSc, MSc, or PhD. Familiarity with chromatographic systems (e.g., FPLC, HPLC), protein characterization methods, and software for data analysis is typically required. Attention to detail, analytical thinking, and effective communication are crucial soft skills for troubleshooting and collaborating with research teams. These competencies ensure the reliable isolation and analysis of proteins, which are fundamental for advancing scientific research and therapeutic development.
More about Research Protein Purification jobs
What states have the most Research Protein Purification jobs? States with the most job openings for Research Protein Purification jobs include:
Infographic showing various Research Protein Purification job openings in the United States as of June 2026, with employment types broken down into 50% As Needed, and 50% Full Time. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $46,222 per year, or $22.2 per hour.
Biologics Process Research & Development Scientist

Biologics Process Research & Development Scientist

MSD

Rahway, NJ

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 3 days ago


Job description

Job Description

Biologics Process Research & Development (BPR&D) within our Company's Research Laboratories is on a mission to rapidly deliver biotherapeutics to patients by efficiently developing innovative, robust manufacturing processes and technologies. To achieve this, we work closely with colleagues in Discovery, Pre-clinical, Early Development, Analytical, Formulation, and Commercial Manufacturing while providing an inclusive environment for all. Beyond process development for pipeline biologics, we innovate and build next generation biomanufacturing technologies. Examples include investments for development of continuous manufacturing, green and sustainable processes, and proprietary technology platforms. We actively publish and engage with the scientific community to influence the field.

Biologics Process Research & Development (BPR&D) includes three lab-facing technical functional areas: Process Cell Sciences (PCS), Upstream Process Development (UPD) and Downstream Process Development & Engineering (DPDE). This job posting covers opportunities for all three functional areas. We are actively looking for highly motivated people with a passion for innovation and interest in contributing to one or more of the three technical functional areas mentioned above.

As a Scientist in Biologics Process Research & Development (BPR&D), you will work with immensely creative and collaborative team members to design and develop robust processes in support of early- and late-stage biologics. You will innovate to support our company's biologics pipeline and production platforms through rigorous scientific principles. You will have the opportunity to apply and integrate innovation into biologic process sciences to establish our company as the industry leader in next-generation biologics manufacturing. You may also be expected to contribute to additional areas of interest such as biophysical, reactor, process, economic and/or multivariate modeling as we are committed to leveraging digital ways of working to enhance our ability to design robust processes.

Responsibilities include but are not limited to:

Develop innovative and disruptive technologies for next-generation biologics manufacturing processes

Develop and characterize robust clinical processes capable of delivering multi-kilogram quantities of therapeutics

Design and conduct experiments related to cell-line development, upstream or downstream bioprocessing

Integrate unit operations with relevant process control and monitoring platforms

Collaborate across Biologics Process Research & DevelopmentBPR&D, process analytics, and other functional areas in research and manufacturing to advance the biologics pipeline

Conduct laboratory- and/or pilot-scale studies to support scale-up and technology transfer to manufacturing sites

Contribute to a safe and compliant laboratory work environment

MINIMUM EDUCATION REQUIREMENTS:

Education:

Bachelor's Degree with 2+ years of relevant experience or master's degree in chemical/Biochemical/Biomedical Engineering, Biotechnology, Biochemistry, Molecular Biology, or related fields with research background in molecular biology, cell culture or protein purification

REQUIRED EXPERIENCE AND SKILLS:

Experience with one or more of molecular biology, protein expression, mammalian cell culture, protein purification, biochemical engineering, or analytical technologies

Scientific understanding of the engineering principles behind recombinant protein production and purification

Ability to comprehend and execute experiments independently

Ability to organize, communicate, analyze, and present experimental data to drive conclusions and further study designs

Knowledge of aseptic technique, protein biophysical properties, and general protein laboratory practices

Demonstrated ability to independently prepare technical documents and scientific presentations to capture development progress, scientific investigations, and technology development output

Basic understanding of statistical methods and data analysis tools

Strong passion and commitment to integrate science and innovation into biologic process development

Ability to excel in a collaborative and matrix environment

PREFERRED EXPERIENCE AND SKILLS:

Demonstrated capabilities in understanding and operating bioanalytical techniques to characterize microbial or cell culture processes

Ability to think critically with excellent problem solving and troubleshooting skills

High throughput screening, automated bioreactor systems, and liquid handlers

Experience with process transfer to clinical or commercial manufacturing facilities

Knowledge of process control and workflow automation tools

Strong foundation in statistical analysis, design of experiments, data science, computational modeling

#BPRD #PRD

Required Skills:

Aseptic Technique, Aseptic Technique, Bioanalytical Techniques, Biomanufacturing, Bioreactor Operation, Cell Culture Process Development, Cell Cultures, Conducting Experiments, Cross-Functional Teamwork, GMP Compliance, High Throughput Screening HTS Systems, Mammalian Cell, Mammalian Cell Culture, Manufacturing Processes, Microbial Fermentation, Molecular Biology, Optimism, Process Optimization, Process Scale Up, Process Scheduling, Product Development, Protein Expression, Protein Purifications, Technical Leadership, Technical Transfer {+ 2 more}

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

The salary range for this role is

$87,300.00 - $137,400.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

05/15/2026

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.