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Research Protein Purification Jobs (NOW HIRING)

... we research, manufacture, and deliver innovative medicines to help people live longer, fuller ... Develop and optimize purification protocols and reagents, ensuring high protein purity, homogeneity ...

$100 - $125/hr

## Associate Scientist, Protein EngineeringApplylocations: Cambridge, MA, UStime type: Full timeposted ... Support purification of recombinant proteins to assist discovery programs from early research ...

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Research Protein Purification information

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How much do research protein purification jobs pay per hour?

As of Sep 8, 2026, the average hourly pay for research protein purification in the United States is $22.22, according to ZipRecruiter salary data. Most workers in this role earn between $17.31 and $23.80 per hour, depending on experience, location, and employer.

What is research protein purification?

Research protein purification is the process of isolating a specific protein from a complex mixture, such as cells or tissues, for study or use in experiments. This process involves several steps, including extraction, separation, and analysis, to obtain a highly pure and functional protein. Protein purification is crucial in biochemical and pharmaceutical research, as it enables scientists to study protein structure, function, and interactions. Techniques used include chromatography, electrophoresis, and centrifugation, among others. Mastery of protein purification methods is essential for producing proteins for drug development, diagnostics, and basic research.

What are the key skills and qualifications needed to thrive in research protein purification?

To excel in Research Protein Purification, you need a solid background in biochemistry or molecular biology, hands-on laboratory experience, and a relevant degree such as a BSc, MSc, or PhD. Familiarity with chromatographic systems (e.g., FPLC, HPLC), protein characterization methods, and software for data analysis is typically required. Attention to detail, analytical thinking, and effective communication are crucial soft skills for troubleshooting and collaborating with research teams. These competencies ensure the reliable isolation and analysis of proteins, which are fundamental for advancing scientific research and therapeutic development.

What are some common challenges faced during protein purification in a research setting, and how can they be addressed?

One common challenge in research protein purification is maintaining protein stability and activity throughout the process, as proteins can denature or degrade easily. Another issue is achieving sufficient yield and purity, especially when working with low-expression proteins or complex mixtures. Overcoming these challenges often involves optimizing buffer conditions, choosing the right purification methods (such as affinity, ion-exchange, or size-exclusion chromatography), and troubleshooting at each step. Collaborating closely with colleagues in molecular biology, biochemistry, and analytical teams is also essential for problem-solving and method development.

What is the difference between Research Protein Purification vs Research Biochemistry Technician?

AspectResearch Protein PurificationResearch Biochemistry Technician
CredentialsBachelor's or Master's in Biochemistry, Molecular Biology, or related fieldsBachelor's degree in Biochemistry, Chemistry, or related sciences
Work EnvironmentLaboratories focused on protein isolation, purification, and analysisLaboratories conducting biochemical experiments, sample preparation, and analysis
Industry UsagePharmaceutical, biotech, academic researchResearch institutions, biotech companies, academic labs
Common Search/ComparisonResearch Protein PurificationResearch Biochemistry Technician

Research Protein Purification specialists focus specifically on isolating and purifying proteins for experiments, often requiring specialized techniques and equipment. Research Biochemistry Technicians perform broader biochemical tasks, including sample preparation and analysis. While both roles work in laboratory settings within similar industries, their core responsibilities and skill sets differ slightly, with protein purification being more specialized.

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What states have the most Research Protein Purification jobs?

States with the most job openings for Research Protein Purification jobs include:

What job categories do people searching Research Protein Purification jobs look for?

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What other helpful pages are available for Research Protein Purification?

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Infographic showing various Research Protein Purification job openings in the United States as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 88% Full Time, 9% Part Time, and 1% Contract. Highlights an 79% Physical, 3% Hybrid, and 18% Remote job distribution, with an average salary of $46,222 per year, or $22.2 per hour.

Production Scientist 3 - Protein Purification

Promega

Madison, WI • On-site

$100 - $125/hr

Other

Re-posted 4 days ago


Promega rating

8.9

Company rating: 8.9 out of 10

Based on 8 frontline employees who took The Breakroom Quiz


Job description

OUR TEAM:

The Protein Purification Team at Promega manufactures proteins and other reagents that are critical to our life science products, which support research and health applications worldwide. Our team works in a modern facility that supports cutting-edge research and development, and we foster an inclusive, supportive environment where all team member's contributions are valued. We are also committed to a healthy work-life balance because our team's well-being is essential to our success. If you are a motivated scientist who is detail-oriented, enjoys a challenge, and thrives in a collaborative setting, you could be an excellent fit for our production environment.

YOUR ROLE:

As a member of our Protein Purification Team, you will manufacture a diverse array of products essential to Promega's product portfolio. You will conduct QC assays to verify that these proteins meet quality specifications and perform as expected. Beyond your core manufacturing duties, you will collaborate with multidisciplinary teams to resolve production challenges, drive process improvements, and support the launch of new products. This role offers a direct opportunity to impact both the quality of our products and the efficiency of our processes as we continue to meet the evolving needs of the communities we serve.

CORE DUTIES:
  1. Independently manufactures a variety of products to meet product specifications. Follows production schedules and plans production batches to ensure on-time delivery of finished product. Responds to changing needs or priorities of the business.
  2. Performs assays to ensure that products meet existing quality control requirements. This includes evaluation of raw materials when necessary. Performs troubleshooting by conducting technical assessments of products and makes recommendations to appropriate person/team/area/etc.
  3. Designs experiments to problem solve and improve existing manufacturing and QC processes. Implements experimental design and perform data analysis. Use all available scientific and technical resources to recommend solutions and solve problems.
  4. Participates in multidisciplinary product improvement or development teams by providing information and technical support to meet team goals. May help develop project plans for work area and analyze operational and cost impacts of process/product improvements. Communicates project updates and issues to supervisor. Interacts as needed with Marketing, QA, and R&D personnel to identify customer requirements for new products and process improvements.
  5. Demonstrates an understanding of quality requirements that relate to both business needs and regulatory standards. Demonstrates good documentation practices and consistently produces quality products and documentation. Follows existing policies for data recording and record keeping.
  6. Writes, reviews, and revises protocols and SOPs for clarity, appropriate technical content, process improvements, scale-up, and/or raw material changes.
  7. Demonstrates inclusion through their own words and actions and is accountable for a safe workspace. Acts with kindness, curiosity and respect for others.
  8. Embraces and is open to incorporating Promega’s 6 Emotional & Social Intelligence (ESI) core principles in daily work.
  9. Understands and complies with ethical, legal, and regulatory requirements applicable to our business.
KEY QUALIFICATIONS:
  1. D., B.S., or M.S. degree in a scientific discipline (e.g., Biochemistry, Biotechnology, Molecular Biology, Microbiology). Degree and 5+ years of postgraduate lab experience in industrial manufacturing operations as reflected in a proven record of accomplishment in the Core Duties of this position are used to determine qualification.
  2. Documented record of accomplishment in experimental design and problem solving relevant to this position.
  3. Ability to interpret and communicate scientific results and interact productively with others on the team. Independently solves interpersonal conflicts and contributes to achievement and success of a team.
  4. Excellent multi-tasking skills, ability to effectively work on several projects and/or products.
  5. Excellent organizational, interpersonal, written, and verbal communication skills.
  6. Ability to use a computer/Microsoft Office applications.
  7. Demonstrated proficiency in digital tools and technology, including Microsoft applications and mobile platforms, with the ability to adapt and leverage emerging technologies, such as artificial intelligence, to improve efficiency, automation, and collaboration.
PREFERRED QUALIFICATIONS:
  1. Prior industry experience.
  2. Experience with ISO 9001 or cGMP Quality System requirements (e.g., complaint investigation, nonconformance, change control).
  3. Experience with use of computers for collection and analysis of experimental data.
  4. Is a self-starter, creative, and capable of initiating and implementing methods to accomplish the requirements of this position.
PHYSICAL DEMANDS:
  1. Ability to work at a laboratory bench for extended periods of time.
  2. Ability to work with hazardous materials (e.g., chemicals, radioactivity, electrical equipment) so as not to endanger oneself or others.
  3. Ability to use standard laboratory protective equipment.

At Promega, we value diversity and strive to create an inclusive workplace. We are proud to be an Equal Opportunity Employer, making employment decisions without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran status, disability, or any other protected class.

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