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Program Integrity Director Jobs in Pittsburgh, PA

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Program Integrity Director information

See Pittsburgh, PA salary details

$28.6K

$75.9K

$133K

How much do program integrity director jobs pay per year?

As of Aug 16, 2026, the average yearly pay for program integrity director in Pittsburgh, PA is $75,914.00, according to ZipRecruiter salary data. Most workers in this role earn between $51,500.00 and $89,800.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a program integrity director, and why are they important?

To thrive as a Program Integrity Director, you need expertise in compliance, risk management, regulatory analysis, and a relevant degree such as in business administration, public policy, or law. Familiarity with data analytics tools, case management systems, and certifications like Certified Fraud Examiner (CFE) or Certified Internal Auditor (CIA) are often important. Strong leadership, ethical judgment, and effective communication skills are crucial for building trust and guiding teams through complex investigations. These skills ensure the organization maintains regulatory compliance, prevents fraud, and promotes operational transparency.

What is the difference between Program Integrity Director vs Claims Manager?

AspectProgram Integrity DirectorClaims Manager
Required CredentialsBachelor's degree, certifications in healthcare compliance or auditingBachelor's degree, experience in claims processing or insurance
Work EnvironmentHealthcare or insurance organizations, compliance departmentsInsurance companies, healthcare payers, claims processing units
Employer & Industry UsageUsed in healthcare, government programs, insurance sectorsPrimarily in insurance companies and healthcare payers

The Program Integrity Director focuses on ensuring compliance, preventing fraud, and maintaining program integrity within healthcare or insurance organizations. In contrast, Claims Managers oversee the processing and adjudication of insurance claims. While both roles require knowledge of healthcare or insurance operations, the Program Integrity Director emphasizes compliance and fraud prevention, whereas the Claims Manager concentrates on claims processing efficiency and accuracy.

What is a program integrity director?

Program Integrity Directors are responsible for overseeing and ensuring the compliance, effectiveness, and accountability of organizational programs, often within government agencies or large organizations. They develop and implement policies to prevent fraud, waste, and abuse, and they monitor program operations to ensure adherence to regulations and standards. Program Integrity Directors often lead teams, conduct audits, and collaborate with other departments to promote transparency and ethical practices. Their work is crucial for maintaining public trust and ensuring resources are used appropriately.

What are some typical challenges faced by a program integrity director, and how can they be addressed?

Program Integrity Directors often face challenges such as navigating complex regulatory requirements, detecting and preventing fraud, and ensuring compliance across multiple departments or partners. Addressing these requires strong analytical skills, clear communication, and effective collaboration with legal, compliance, and operational teams. Staying updated on industry best practices and fostering a culture of transparency can also help mitigate risks and support program goals.

What are popular job titles related to Program Integrity Director jobs in Pittsburgh, PA?

For Program Integrity Director jobs in Pittsburgh, PA, the most frequently searched job titles are:

What job categories do people searching Program Integrity Director jobs in Pittsburgh, PA look for?

The top searched job categories for Program Integrity Director jobs in Pittsburgh, PA are:

What cities near Pittsburgh, PA are hiring for Program Integrity Director jobs?

Cities near Pittsburgh, PA with the most Program Integrity Director job openings:

Infographic showing various Program Integrity Director job openings in Pittsburgh, PA as of August 2026, with employment types broken down into 1% As Needed, 77% Full Time, 17% Part Time, 1% Temporary, and 4% Contract. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution, with an average salary of $75,914 per year, or $36.5 per hour.

Medical Director/Senior Medical Director (Clinical Development)

Krystal Biotech

Pittsburgh, PA โ€ข On-site

Full-time

Posted 23 days ago


Job description

Medical Director/Senior Medical Director (Clinical Development)
About Krystal Bio: At Krystal Biotech, we bring together the brightest and most eager minds to relentlessly pursue the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs. 
Founded in 2016, Krystal is distinguished in three powerful ways: science and technology using our patented gene therapy platform, innovative manufacturing supported by our commercial scale facilities, and a unique commercialization model that focuses on the patient’s end to end experience.
Krystal received U.S. FDA approval for the first and only redosable gene therapy treatment, VYJUVEK®, for the treatment of Dystrophic Epidermolysis Bullosa (DEB). Krystal continues to leverage our proprietary platform to rapidly advance a robust pipeline of investigational genetic medicines in respiratory, oncology, dermatology, and ophthalmology. 
Krystal is headquartered in Pittsburgh, PA which is home to our two state-of-the-art CGMP manufacturing facilities with teams around the world and satellite offices in Switzerland, Germany, and Japan. We are a company built and run by people who care, are fearless in the face of a challenge, love the work they do, and practice the highest level of scientific integrity. As we grow, we are seeking team members that embody these values. 
Job Description Summary:
Krystal Biotech, Inc. is seeking a highly skilled and motivated Medical Director/Senior Director (Clinical Development) to lead and oversee clinical research activities. The ideal candidate will have a significant role in clinical trial management and furthering the development of Krystal’s pipeline programs.  This role will be based in Krystal’s headquarters in Pittsburgh, PA.
Responsibilities will include, but are not limited to, the following:
  • Lead the planning, design, execution, and management of clinical trials from Phase I through Phase III, ensuring compliance with regulatory requirements and timelines.
  • Serve as point of contact with key opinion leaders and at scientific/regulatory meetings.
  • Support patient recruitment on assigned clinical programs, including recruitment strategy and execution in tandem with clinical sites.
  • Develop clinical trial protocols, investigator brochures, and other study-related materials.
  • Oversee site selection, study initiation, monitoring, and close-out activities in collaboration with the clinical operations team.
  • Support interactions with regulatory authorities, including meeting preparation, attendance, and authoring responses to information requests.
  • Ensure adherence to Good Clinical Practice (GCP) guidelines and other regulatory standards.
  • Collaborate with cross-functional teams, including regulatory affairs, biostatistics, data management, and medical writing, to ensure successful trial execution.
  • Manage relationships with clinical research organizations (CROs), investigators, and study sites.
  • Monitor clinical trial budgets and timelines, ensuring studies are conducted within scope and on budget.
  • Review and interpret clinical trial data, providing clinical and scientific expertise to project teams and ensuring resolution of data related issues during data and protocol deviation reviews.
  • Contribute to the preparation of clinical study reports, regulatory submissions, and publications.
  • Stay current with industry trends and advancements in clinical research and gene therapy.
  • Provide leadership and mentorship to clinical research staff, fostering a culture of excellence and continuous improvement.
Requirements and Preferred Qualifications:
  • A Medical Degree (MD) in a related field is required.
  • 2+ years of experience in clinical research.
  • Experience working on clinical trials in the biotechnology or pharmaceutical industry is a plus.
  • Strong knowledge of Good Clinical Practice (GCP) guidelines and regulatory requirements.
  • Excellent organizational, analytical, and problem-solving skills.
  • Strong attention to detail and accuracy.
  • Ability to work independently and as part of a team.
  • Strong interpersonal and communication skills, with the ability to work effectively with cross-functional teams.
  • Proficiency in Microsoft Office Suite and clinical trial management software.
  • Willingness to travel as required.

 

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